Nicholas C. Wu

Best Publications

• A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV.

  Meng Yuan;Nicholas C. Wu;Xueyong Zhu;Chang Chun D. Lee

  1642
  Citations

• Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model.

  Thomas F. Rogers;Thomas F. Rogers;Fangzhu Zhao;Deli Huang;Nathan Beutler

  1373
  Citations

• Structural basis of a shared antibody response to SARS-CoV-2.

  Meng Yuan;Hejun Liu;Nicholas C. Wu;Chang Chun D. Lee

  647
  Citations

• Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling

  Autumn G. York;Kevin J. Williams;Joseph P. Argus;Quan D. Zhou

  472
  Citations

• Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections.

  Huibin Lv;Nicholas C. Wu;Owen Tak Yin Tsang;Meng Yuan

  454
  Citations

• Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape.

  Paul-Albert Koenig;Hrishikesh Das;Hejun Liu;Beate M. Kümmerer

  414
  Citations

• Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants.

  Meng Yuan;Deli Huang;Chang Chun D. Lee;Nicholas C. Wu

  392
  Citations

• Serological assays for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), March 2020.

  Ranawaka A.P.M. Perera;Chris K.P. Mok;Owen T.Y. Tsang;Huibin Lv

  375
  Citations

• A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.

  Jakob Kreye;S. Momsen Reincke;Hans Christian Kornau;Hans Christian Kornau;Elisa Sánchez-Sendin;Elisa Sánchez-Sendin;Elisa Sánchez-Sendin

  340
  Citations

• A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure

  Jeong Hyun Lee;Jeong Hyun Lee;Raiees Andrabi;Raiees Andrabi;Ching Yao Su;Anila Yasmeen

  259
  Citations

• A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.

  Nicholas C. Wu;Seth J. Zost;Andrew J. Thompson;David Oyen

  253
  Citations

• Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity.

  Hejun Liu;Nicholas C. Wu;Meng Yuan;Sandhya Bangaru

  238
  Citations

• Deep mutational scanning of hemagglutinin helps predict evolutionary fates of human H3N2 influenza variants.

  Juhye M. Lee;Juhye M. Lee;John Huddleston;John Huddleston;Michael B. Doud;Michael B. Doud;Kathryn A. Hooper;Kathryn A. Hooper

  230
  Citations

• Influenza Hemagglutinin Structures and Antibody Recognition

  Nicholas C. Wu;Ian A. Wilson

  213
  Citations

• Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies.

  Meng Yuan;Hejun Liu;Nicholas C. Wu;Ian A. Wilson

  207
  Citations

• A Perspective on the Structural and Functional Constraints for Immune Evasion: Insights from Influenza Virus.

  Nicholas C. Wu;Ian A. Wilson

  192
  Citations

• An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain.

  Nicholas C. Wu;Meng Yuan;Hejun Liu;Chang Chun D. Lee

  182
  Citations

• High-throughput profiling of influenza A virus hemagglutinin gene at single-nucleotide resolution

  Nicholas C. Wu;Arthur P. Young;Laith Q. Al-Mawsawi;C. Anders Olson

  146
  Citations

• Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern.

  Hyeseon Cho;Kristina Kay Gonzales-Wartz;Deli Huang;Meng Yuan

  123
  Citations

• A highly conserved cryptic epitope in the receptor-binding domains of SARS-CoV-2 and SARS-CoV

  Meng Yuan;Nicholas C. Wu;Xueyong Zhu;Chang-Chun D. Lee

  59
  Citations