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D-Index & Metrics

Biology and Biochemistry

D-Index
101
Citations
42005
World Ranking
1421
National Ranking
810

Overview

Lawrence Shapiro is affiliated with Columbia University in the United States. Their research contributions span primarily the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a total of 173 and 110 publications respectively. Within these fields, Shapiro's work extensively covers subfields including Infectious Diseases, Molecular Biology, Radiology, Nuclear Medicine and Imaging, Virology, and Epidemiology.

The core topics of Shapiro's research include:

  • SARS-CoV-2 and COVID-19 Research
  • Monoclonal and Polyclonal Antibodies Research
  • HIV Research and Treatment
  • Viral gastroenteritis research and epidemiology
  • Influenza Virus Research Studies
  • SARS-CoV-2 detection and testing
  • Glycosylation and Glycoproteins Research

Shapiro has published work in a range of academic venues, with notable frequent publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • EMPIAR dataset
  • Structure
  • Cell Host & Microbe

Among recent papers associated with Shapiro are:

  • Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike, 2020, Nature
  • Increased resistance of SARS-CoV-2 variant P.1 to antibody neutralization, 2021, Cell Host & Microbe
  • Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite, 2021, Cell Host & Microbe
  • Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains, 2020, Cell Host & Microbe
  • Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7, 2021, Nature

Frequent coauthors collaborating with Shapiro include:

  • Peter D. Kwong
  • Gabriele Cerutti
  • Zizhang Sheng
  • Tongqing Zhou
  • David D. Ho

In addition to journal publications, Shapiro has contributed to book publications, with titles released by Princeton University Press and Johns Hopkins University, including When Bad Thinking Happens to Good People and When Bad Thinking Happens to Good People: How Philosophy Can Save Us from Ourselves in 2021.

Best Publications

  • Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7.

    Pengfei Wang;Manoj S. Nair;Lihong Liu;Sho Iketani;Sho Iketani

  • Structural basis of cell-cell adhesion by cadherins.

    Lawrence Shapiro;Allison M. Fannon;Peter D. Kwong;Andrew Thompson

  • Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike.

    Lihong Liu;Pengfei Wang;Manoj S. Nair;Jian Yu

  • Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01.

    Tongqing Zhou;Ivelin Georgiev;Xueling Wu;Zhi Yong Yang

  • Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

    Hua-Xin Liao;Rebecca Lynch;Tongqing Zhou;Feng Gao;Feng Gao

  • Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs.

    Tristan Bepler;Andrew Morin;Micah Rapp;Julia Brasch

  • The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor

    Lawrence Shapiro;Philipp E. Scherer

  • Proteomic Analysis of Proteins Associated with Lipid Droplets of Basal and Lipolytically Stimulated 3T3-L1 Adipocytes *

    Dawn L. Brasaemle;Georgia Dolios;Lawrence Shapiro;Rong Wang

  • Increased resistance of SARS-CoV-2 variant P.1 to antibody neutralization.

    Pengfei Wang;Ryan G. Casner;Manoj S. Nair;Maple Wang

  • C-cadherin ectodomain structure and implications for cell adhesion mechanisms

    Titus J. Boggon;John Murray;Sophie Chappuis-Flament;Ellen Wong

  • Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.

    Nicole A. Doria-Rose;Chaim A. Schramm;Jason Gorman;Penny L. Moore

  • Structure and Biochemistry of Cadherins and Catenins

    Lawrence Shapiro;William I. Weis

  • The Presynaptic Particle Web: Ultrastructure, Composition, Dissolution, and Reconstitution

    Greg R Phillips;Jeffrey K Huang;Yun Wang;Hidekazu Tanaka

  • Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.

    Gabriele Cerutti;Yicheng Guo;Tongqing Zhou;Jason Gorman

  • The Extracellular Architecture of Adherens Junctions Revealed by Crystal Structures of Type I Cadherins

    Oliver J. Harrison;Xiangshu Jin;Soonjin Hong;Fabiana Bahna

  • G-Protein Signaling Through Tubby Proteins

    Sandro Santagata;Titus J. Boggon;Cheryl L. Baird;Carlos A. Gomez

  • Crystal structure of the extracellular domain from P0, the major structural protein of peripheral nerve myelin.

    Lawrence Shapiro;Joseph P. Doyle;Preston Hensley;David R. Colman

  • Structure-Function Analysis of Cell Adhesion by Neural (N-) Cadherin

    Kazuyoshi Tamura;Wei-Song Shan;Wayne A. Hendrickson;Wayne A. Hendrickson;David R. Colman

  • Disulfide-dependent multimeric assembly of resistin family hormones

    Saurabh D. Patel;Michael W. Rajala;Z. Luciano Rossetti;Philipp E. Scherer

  • Increased Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 to Antibody Neutralization

    Pengfei Wang;Manoj S Nair;Lihong Liu;Sho Iketani;Sho Iketani

Frequent Co-Authors

Barry Honig
Barry Honig Columbia University
Peter D. Kwong
Peter D. Kwong Columbia University Medical Center
John R. Mascola
John R. Mascola ModeX Therapeutics
Zizhang Sheng
Zizhang Sheng Columbia University
Baoshan Zhang
Baoshan Zhang National Institute of Allergy and Infectious Diseases
Tongqing Zhou
Tongqing Zhou National Institutes of Health
Gwo-Yu Chuang
Gwo-Yu Chuang Moderna Therapeutics (United States)
Lynn Morris
Lynn Morris University of the Witwatersrand
Mark K. Louder
Mark K. Louder National Institute of Allergy and Infectious Diseases
Ivelin S. Georgiev
Ivelin S. Georgiev Vanderbilt University Medical Center

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