Gwo-Yu Chuang

Overview

Best Publications

• Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

  Jason S. McLellan;Man Chen;M. Gordon Joyce;Mallika Sastry

  1134
  Citations

• Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

  Jason S. McLellan;Marie Pancera;Chris Carrico;Jason Gorman

  1061
  Citations

• Structure and immune recognition of trimeric pre-fusion HIV-1 Env

  Marie Pancera;Tongqing Zhou;Aliaksandr Druz;Ivelin S. Georgiev

  867
  Citations

• Fragment-based identification of druggable ‘hot spots’ of proteins using Fourier domain correlation techniques

  Ryan Brenke;Dima Kozakov;Gwo-Yu Chuang;Dmitri Beglov

  531
  Citations

• Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.

  Gabriele Cerutti;Yicheng Guo;Tongqing Zhou;Jason Gorman

  523
  Citations

• Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface

  Jinghe Huang;Byong H. Kang;Marie Pancera;Jeong Hyun Lee

  500
  Citations

• Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B and G

  Guillaume B.E. Stewart-Jones;Cinque Soto;Thomas Lemmin;Thomas Lemmin;Gwo Yu Chuang

  451
  Citations

• Prefusion F–specific antibodies determine the magnitude of RSV neutralizing activity in human sera

  Joan O. Ngwuta;Man Chen;Kayvon Modjarrad;Kayvon Modjarrad;M. Gordon Joyce

  444
  Citations

• Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.

  Tongqing Zhou;Jiang Zhu;Xueling Wu;Stephanie Moquin

  412
  Citations

• Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.

  Jinghe Huang;Byong H. Kang;Elise Ishida;Tongqing Zhou

  406
  Citations

• Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

  Young Do Kwon;Marie Pancera;Priyamvada Acharya;Ivelin S. Georgiev

  392
  Citations

• Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

  Rui Kong;Kai Xu;Tongqing Zhou;Priyamvada Acharya

  371
  Citations

• Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.

  Tongqing Zhou;Yaroslav Tsybovsky;Jason Gorman;Micah Rapp

  371
  Citations

• Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

  M. Gordon Joyce;Adam K. Wheatley;Paul V. Thomas;Gwo-Yu Chuang

  349
  Citations

• Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody

  Mattia Bonsignori;Tongqing Zhou;Zizhang Sheng;Lei Chen

  332
  Citations

• Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo

  Rebecca S. Rudicell;Young Do Kwon;Sung-Youl Ko;Amarendra Pegu

  322
  Citations

• Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.

  K. Xu;P. Acharya;R. Kong;C. Cheng

  298
  Citations

• Structural conservation of druggable hot spots in protein–protein interfaces

  Dima Kozakov;David R. Hall;Gwo-Yu Chuang;Regina Cencic

  289
  Citations

• Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.

  Xueling Wu;Xueling Wu;Zhenhai Zhang;Chaim A. Schramm;M. Gordon Joyce

  278
  Citations

• Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization.

  Ivelin S. Georgiev;Nicole A. Doria-Rose;Tongqing Zhou;Young Do Kwon

  265
  Citations