D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 48 Citations 9,913 101 World Ranking 11550 National Ranking 4958

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Antibody
  • Immune system

His main research concerns Antibody, Virology, Epitope, Neutralization and Glycan. His Antibody research includes themes of Lineage, Immune system, Antigen, Vaccination and Viral protein. His study in Virology focuses on Virus in particular.

Gwo-Yu Chuang combines subjects such as Peptide sequence, Conserved sequence and Neutralizing antibody with his study of Epitope. His research integrates issues of Monoclonal antibody and Binding site in his study of Neutralization. Gwo-Yu Chuang works mostly in the field of Glycan, limiting it down to topics relating to Glycosylation and, in certain cases, Glycoprotein, Antigen-Antibody Complex, Oligosaccharide and Humoral immunity, as a part of the same area of interest.

His most cited work include:

  • Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 (694 citations)
  • Structure and immune recognition of trimeric pre-fusion HIV-1 Env (544 citations)
  • Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus (524 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Antibody, Virology, Neutralization, Epitope and Trimer. His Antibody study incorporates themes from Lineage, Glycosylation and Glycan. His specific area of interest is Virology, where Gwo-Yu Chuang studies Virus.

His work deals with themes such as Glycoprotein and Vaccination, which intersect with Virus. His Neutralization study also includes fields such as

  • Potency which intersects with area such as Immunology,
  • Fusion peptide most often made with reference to Priming. His research integrates issues of Neutralizing antibody, Viral entry, Peptide sequence, Protein structure and Viral protein in his study of Epitope.

He most often published in these fields:

  • Antibody (57.39%)
  • Virology (56.52%)
  • Neutralization (36.52%)

What were the highlights of his more recent work (between 2019-2021)?

  • Antibody (57.39%)
  • Virology (56.52%)
  • Neutralization (36.52%)

In recent papers he was focusing on the following fields of study:

Gwo-Yu Chuang mainly investigates Antibody, Virology, Neutralization, Epitope and Glycan. His study in the field of Somatic hypermutation also crosses realms of Antibody Classes. His Virology study focuses on Vaccination in particular.

His work in Neutralization is not limited to one particular discipline; it also encompasses Neutralizing antibody. His study in Epitope is interdisciplinary in nature, drawing from both Biophysics and Monoclonal antibody. Many of his studies on Glycan involve topics that are commonly interrelated, such as Glycosylation.

Between 2019 and 2021, his most popular works were:

  • Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains. (59 citations)
  • Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite. (33 citations)
  • A pH-dependent switch mediates conformational masking of SARS-CoV-2 spike (32 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Antibody
  • Immune system

His primary areas of study are Virology, Epitope, Antibody, Severe acute respiratory syndrome coronavirus 2 and Antibody Classes. His Virology research is multidisciplinary, incorporating elements of Adjuvant, Immunogen and Peptide. Gwo-Yu Chuang has researched Epitope in several fields, including Neutralization and Neutralizing antibody.

His Neutralization research includes themes of Endosome, Viral envelope, Viral replication and Binding site. The various areas that Gwo-Yu Chuang examines in his Neutralizing antibody study include Globular protein, Biophysics and Binding domain. Gwo-Yu Chuang performs multidisciplinary study on Antibody and Trimer in his works.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

Jason S. McLellan;Marie Pancera;Chris Carrico;Jason Gorman.
Nature (2011)

846 Citations

Structure and immune recognition of trimeric pre-fusion HIV-1 Env

Marie Pancera;Tongqing Zhou;Aliaksandr Druz;Ivelin S. Georgiev.
Nature (2014)

612 Citations

Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

Jason S. McLellan;Man Chen;M. Gordon Joyce;Mallika Sastry.
Science (2013)

505 Citations

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface

Jinghe Huang;Byong H. Kang;Marie Pancera;Jeong Hyun Lee.
Nature (2014)

410 Citations

Fragment-based identification of druggable ‘hot spots’ of proteins using Fourier domain correlation techniques

Ryan Brenke;Dima Kozakov;Gwo-Yu Chuang;Dmitri Beglov.
Bioinformatics (2009)

393 Citations

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B and G

Guillaume B.E. Stewart-Jones;Cinque Soto;Thomas Lemmin;Thomas Lemmin;Gwo Yu Chuang.
Cell (2016)

299 Citations

Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.

Tongqing Zhou;Jiang Zhu;Xueling Wu;Stephanie Moquin.
Immunity (2013)

281 Citations

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

Young Do Kwon;Marie Pancera;Priyamvada Acharya;Ivelin S. Georgiev.
Nature Structural & Molecular Biology (2015)

262 Citations

Structural conservation of druggable hot spots in protein–protein interfaces

Dima Kozakov;David R. Hall;Gwo-Yu Chuang;Regina Cencic.
Proceedings of the National Academy of Sciences of the United States of America (2011)

231 Citations

Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo

Rebecca S. Rudicell;Young Do Kwon;Sung-Youl Ko;Amarendra Pegu.
Journal of Virology (2014)

225 Citations

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