His primary scientific interests are in Virology, Antibody, Epitope, Immunogen and Antigen. His study in Virology is interdisciplinary in nature, drawing from both Immunization and Immunology. His Antibody study combines topics in areas such as Germline, Immune system and Glycoprotein.
His Epitope study incorporates themes from Glycosylation, Antigenicity, Peptide sequence, Glycan and Viral protein. His Immunogen study integrates concerns from other disciplines, such as Priming and Germinal center, B cell. His Antigen research includes themes of Virus and B-cell receptor.
His primary areas of investigation include Virology, Antibody, Epitope, Antigen and Immunogen. His Virology research is multidisciplinary, relying on both Immunization, Immune system, B cell, Monoclonal antibody and Binding site. The Antibody study combines topics in areas such as Glycoprotein and Glycan.
His biological study spans a wide range of topics, including Glycosylation and Cell biology. His research in Epitope intersects with topics in Protein structure, Virus, Scaffold protein and Scaffold. His research investigates the connection with Antigen and areas like Protein design which intersect with concerns in Biological system.
William R. Schief focuses on Antibody, Virology, Antigen, Germinal center and B cell. His study in Glycan extends to Antibody with its themes. The study incorporates disciplines such as MEDLINE, Monoclonal antibody and Immunogenicity in addition to Virology.
His Antigen research includes themes of Adjuvant, Cancer research, Immune system and DNA origami. His research integrates issues of Immunization and Immunodominance in his study of B cell. His research on Epitope often connects related areas such as Glycoprotein.
William R. Schief mainly investigates Germinal center, Antigen, Antibody, Virology and B cell. His studies in Antigen integrate themes in fields like Immunogen, Vaccine efficacy, DNA origami and Cell biology. His study in Affinity maturation, Neutralization, Epitope and Neutralizing antibody falls under the purview of Antibody.
His Neutralization research integrates issues from Lineage, Monoclonal antibody, Binding site and Glycan. His study in Epitope is interdisciplinary in nature, drawing from both Glycoprotein, Biophysics, Ectodomain and Transmembrane protein. His Virology research incorporates elements of Priming and Immunogenicity.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1
Xueling Wu;Zhi Yong Yang;Yuxing Li;Carl Magnus Hogerkorp.
Science (2010)
Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9
Jason S. McLellan;Marie Pancera;Chris Carrico;Jason Gorman.
Nature (2011)
A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield
Robert Pejchal;Katie J. Doores;Katie J. Doores;Laura M. Walker;Reza Khayat.
Science (2011)
Rational HIV immunogen design to target specific germline B cell receptors
Joseph Jardine;Jean Philippe Julien;Jean Philippe Julien;Sergey Menis;Takayuki Ota.
Science (2013)
Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2
Morgane Rolland;Paul T. Edlefsen;Brendan B. Larsen;Sodsai Tovanabutra.
Nature (2012)
Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility
Marie Pancera;Shahzad Majeed;Yih-En Andrew Ban;Lei Chen.
Proceedings of the National Academy of Sciences of the United States of America (2010)
HIV-1 neutralizing antibodies induced by native-like envelope trimers
Rogier W. Sanders;Rogier W. Sanders;Marit J. Van Gils;Ronald Derking;Devin Sok;Devin Sok.
Science (2015)
A Blueprint for HIV Vaccine Discovery
Dennis R. Burton;Rafi Ahmed;Rafi Ahmed;Dan H. Barouch;Dan H. Barouch;Dan H. Barouch;Salvatore T. Butera.
Cell Host & Microbe (2012)
Proof of principle for epitope-focused vaccine design
Bruno Emanuel F. Sousa Correia;John T. Bates;Rebecca J. Loomis;Gretchen Baneyx.
Nature (2014)
Elicitation of structure-specific antibodies by epitope scaffolds
Gilad Ofek;F. Javier Guenaga;William R. Schief;Jeff Skinner.
Proceedings of the National Academy of Sciences of the United States of America (2010)
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