World's Best Scientists 2026 revealed!
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Biology and Biochemistry
USA
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
85
Citations
24374
World Ranking
3169
National Ranking
1598

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in United States Leader Award
  • 2021 - Breakthrough Prize in Life Sciences for developing technology that allowed the design of proteins never seen before in nature, including novel proteins that have the potential for therapeutic intervention in human diseases.
  • 2020 - Fellow of the Indian National Academy of Engineering (INAE)
  • 2009 - Fellow of the American Academy of Arts and Sciences
  • 2006 - Member of the National Academy of Sciences

Overview

David Baker is affiliated with the University of Washington in the United States and focuses primarily on medicine, with a significant number of publications in pathology and forensic medicine, immunology, molecular biology, oncology, and infectious diseases. Their research spans multiple topics, particularly in multiple sclerosis studies, COVID-19 and SARS-CoV-2 research, immunotherapy and immune responses, polyomavirus-related diseases, peripheral neuropathies and disorders, neurogenesis and neuroplasticity mechanisms, and monoclonal and polyclonal antibodies research.

Several recent papers by David Baker include the following:

  • COVID-19 vaccine-readiness for anti-CD20-depleting therapy in autoimmune diseases, 2020, Clinical & Experimental Immunology
  • The ocrelizumab phase II extension trial suggests the potential to improve the risk: benefit balance in multiple sclerosis, 2020, Multiple Sclerosis and Related Disorders

They have frequently collaborated with researchers such as Gavin Giovannoni, Klaus Schmierer, Angray S. Kang, Sharmilee Gnanapavan, and Mónica Marta.

Their work has been published extensively in venues including Multiple Sclerosis and Related Disorders, bioRxiv (Cold Spring Harbor Laboratory), Clinical & Experimental Immunology, Journal of Neurology Neurosurgery & Psychiatry, and Human Antibodies.

David Baker's contributions are recognized through several awards, such as the Breakthrough Prize in Life Sciences in 2021 for developing technology that enabled the design of novel proteins with potential therapeutic applications. Additional honors include being named a Fellow of the Indian National Academy of Engineering (INAE) in 2020, a Fellow of the American Academy of Arts and Sciences in 2009, and a Member of the National Academy of Sciences since 2006.

Best Publications

  • Inflammation in neurodegenerative diseases

    Sandra Amor;Sandra Amor;Fabiola Puentes;David Baker;Paul van der Valk

  • Pharmaco-metabonomic phenotyping and personalized drug treatment.

    T. Andrew Clayton;John C. Lindon;Olivier Cloarec;Henrik Antti

  • Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism

    T. Andrew Clayton;David Baker;John C. Lindon;Jeremy R. Everett

  • Cannabinoids control spasticity and tremor in a multiple sclerosis model.

    D Baker;G Pryce;J L Croxford;P Brown

  • Inflammation in neurodegenerative diseases – an update

    Sandra Amor;Sandra Amor;Laura A. N. Peferoen;Daphne Y. S. Vogel;Marjolein Breur

  • IMMUNOHISTOCHEMICAL LOCALIZATION OF CANNABINOID TYPE 1 AND VANILLOID TRANSIENT RECEPTOR POTENTIAL VANILLOID TYPE 1 RECEPTORS IN THE MOUSE BRAIN

    L. Cristino;L. de Petrocellis;G. Pryce;D. Baker

  • The therapeutic potential of cannabis

    David Baker;Gareth Pryce;Gavin Giovannoni;Alan J Thompson

  • Identification of epitopes of myelin oligodendrocyte glycoprotein for the induction of experimental allergic encephalomyelitis in SJL and Biozzi AB/H mice.

    S Amor;N Groome;C Linington;M M Morris

  • Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells.

    Katarzyna Maresz;Gareth Pryce;Gareth Pryce;Eugene D Ponomarev;Giovanni Marsicano

  • Cannabinoids inhibit neurodegeneration in models of multiple sclerosis

    Gareth Pryce;Zubair Ahmed;Deborah J. R. Hankey;Samuel J. Jackson

  • In silico patent searching reveals a new cannabinoid receptor.

    David Baker;Gareth Pryce;Wayne L. Davies;C. Robin Hiley

  • Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors

    Aymen I Idris;Aymen I Idris;Robert J van 't Hof;Robert J van 't Hof;Iain R Greig;Susan A Ridge

  • Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor-immunoglobulin fusion proteins.

    David Baker;Debra Butler;Bernard J. Scallon;Janet K. O'Neill

  • Two years later: journals are not yet enforcing the ARRIVE guidelines on reporting standards for pre-clinical animal studies.

    David Baker;Katie Lidster;Ana Sottomayor;Sandra Amor

  • Novel gut-based pharmacology of metformin in patients with type 2 diabetes mellitus.

    Antonella Napolitano;Sam Miller;Andrew W. Nicholls;David Baker

  • Lovastatin inhibits brain endothelial cell Rho-mediated lymphocyte migration and attenuates experimental autoimmune encephalomyelitis

    John Greenwood;Claire E. Walters;Gareth Pryce;Naheed Kanuga

  • Memory B Cells are Major Targets for Effective Immunotherapy in Relapsing Multiple Sclerosis

    David Baker;Monica Marta;Gareth Pryce;Gavin Giovannoni

  • MicroRNA-155 negatively affects blood–brain barrier function during neuroinflammation

    Miguel Alejandro Lopez-Ramirez;Dongsheng Wu;Gareth Pryce;Julie E. Simpson

  • Induction of chronic relapsing experimental allergic encephalomyelitis in Biozzi mice

    D. Baker;J.K. O'Neill;S.E. Gschmeissner;C.E. Wilcox

  • Interpreting Lymphocyte Reconstitution Data From the Pivotal Phase 3 Trials of Alemtuzumab.

    David Baker;Samuel S. Herrod;Cesar Alvarez-Gonzalez;Gavin Giovannoni;Gavin Giovannoni

Frequent Co-Authors

Gavin Giovannoni
Gavin Giovannoni Queen Mary University of London
Gareth Pryce
Gareth Pryce Queen Mary University of London
Frank DiMaio
Frank DiMaio University of Washington
Sandra Amor
Sandra Amor University of Amsterdam
Gaetano T. Montelione
Gaetano T. Montelione Rensselaer Polytechnic Institute
Brian Kuhlman
Brian Kuhlman University of North Carolina at Chapel Hill
Tanja Kortemme
Tanja Kortemme University of California, San Francisco
William R. Schief
William R. Schief Scripps Research Institute
Rong Xiao
Rong Xiao Rutgers, The State University of New Jersey
Todd O. Yeates
Todd O. Yeates University of California, Los Angeles

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