What is he best known for?
The fields of study he is best known for:
- Quantum mechanics
- Gene
- DNA
His scientific interests lie mostly in Protein folding, Folding, Phi value analysis, Native state and Crystallography.
Eugene I. Shakhnovich combines subjects such as Chemical physics, Thermodynamics, Statistical physics, Protein structure and Levinthal's paradox with his study of Protein folding.
Eugene I. Shakhnovich interconnects Helix, Cooperativity, Gene and Lattice monte carlo in the investigation of issues within Folding.
His Phi value analysis research includes elements of Contact order and Nucleus.
His Native state study incorporates themes from Random coil, Protein engineering and Biological system.
His study looks at the intersection of Crystallography and topics like Molecular dynamics with Globular protein.
His most cited work include:
- How does a protein fold (783 citations)
- Kinetics of protein folding. A lattice model study of the requirements for folding to the native state. (481 citations)
- Engineering of stable and fast-folding sequences of model proteins (450 citations)
What are the main themes of his work throughout his whole career to date?
Eugene I. Shakhnovich mainly focuses on Protein folding, Statistical physics, Protein structure, Genetics and Folding.
His work deals with themes such as Crystallography, Native state and Chemical physics, which intersect with Protein folding.
In most of his Statistical physics studies, his work intersects topics such as Monte Carlo method.
As part of his studies on Protein structure, Eugene I. Shakhnovich often connects relevant areas like Computational biology.
His Genetics study combines topics from a wide range of disciplines, such as Evolutionary biology and Fitness landscape.
His Contact order study integrates concerns from other disciplines, such as Lattice protein and Downhill folding.
He most often published in these fields:
- Protein folding (29.55%)
- Statistical physics (14.57%)
- Protein structure (14.57%)
What were the highlights of his more recent work (between 2017-2021)?
- Biophysics (10.12%)
- Protein folding (29.55%)
- Dihydrofolate reductase (4.05%)
In recent papers he was focusing on the following fields of study:
Biophysics, Protein folding, Dihydrofolate reductase, Mutant and Crystallin are his primary areas of study.
His Biophysics research integrates issues from Protein aggregation, Disulfide bond, Folding, Substrate and Adenylate kinase.
His research integrates issues of Protein structure and Protein domain in his study of Protein folding.
His Dihydrofolate reductase research also works with subjects such as
- Auxotrophy that intertwine with fields like Essential gene and Evolutionary dynamics,
- Phenotype and related Point mutation.
His Crystallin research is multidisciplinary, relying on both Catalysis and Disulfide exchange.
The various areas that Eugene I. Shakhnovich examines in his Contact order study include Computational biology and Gene.
Between 2017 and 2021, his most popular works were:
- Common activation mechanism of class A GPCRs. (47 citations)
- Accessibility of the Shine-Dalgarno Sequence Dictates N-Terminal Codon Bias in E. coli (35 citations)
- Differential Enzyme Flexibility Probed Using Solid-State Nanopores (33 citations)
In his most recent research, the most cited papers focused on:
- Quantum mechanics
- Gene
- DNA
His main research concerns Biophysics, Protein folding, Genetics, Gene and Evolutionary ecology.
The concepts of his Biophysics study are interwoven with issues in Mutant, Crystallin, Adenylate kinase and Substrate.
Eugene I. Shakhnovich has researched Protein folding in several fields, including Protein structure, Protein domain, Computational biology and Protein aggregation.
His study on Lineage, Hemagglutinin, Influenza vaccine and Nucleoprotein is often connected to Selective sweep as part of broader study in Genetics.
The study incorporates disciplines such as Contact order, Native structure and Translocon in addition to Gene.
He has included themes like Range and Competition in his Evolutionary ecology study.
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