2022 - Research.com Best Female Scientist Award
2022 - Research.com Best Scientist Award
2020 - Fellow of American Physical Society (APS) Citation For extraordinary advancements in the understanding of the structure and function of biomacromolecules, an algorithm for predicting RNA secondary structure, and the Conformational Selection and Population Shift concept as an alternative to the InducedFit model in molecular recognition
2013 - Fellow of the International Society for Computational Biology
Ruth Nussinov mainly focuses on Protein structure, Crystallography, Protein folding, Biophysics and Docking. Her Protein structure research includes themes of Plasma protein binding, Allosteric regulation and Binding site. The various areas that Ruth Nussinov examines in her Crystallography study include Hydrophobic effect, Salt bridge, Hydrogen bond and Protein–protein interaction.
Ruth Nussinov works mostly in the field of Protein folding, limiting it down to topics relating to Chemical physics and, in certain cases, Molecular dynamics. Her study in Biophysics is interdisciplinary in nature, drawing from both Hydrophobic collapse, Peptide and Amyloid. The study incorporates disciplines such as Algorithm and Hinge in addition to Docking.
Her primary scientific interests are in Protein structure, Biophysics, Crystallography, Computational biology and Biochemistry. Her studies deal with areas such as Plasma protein binding, Docking, Protein folding, Peptide sequence and Binding site as well as Protein structure. Her work deals with themes such as Folding, Hydrophobic effect and Folding, which intersect with Protein folding.
In her study, Signal transduction is inextricably linked to Allosteric regulation, which falls within the broad field of Biophysics. While the research belongs to areas of Crystallography, Ruth Nussinov spends her time largely on the problem of Molecular dynamics, intersecting her research to questions surrounding Stereochemistry. Her Computational biology research includes elements of Genetics, Function, Protein–protein interaction and Bioinformatics, Drug discovery.
The scientist’s investigation covers issues in Biophysics, Cell biology, Computational biology, Allosteric regulation and PI3K/AKT/mTOR pathway. Her Biophysics research integrates issues from Protein structure, Membrane, Biochemistry and Molecular dynamics. Her research integrates issues of Enzyme activator, Protein domain and Tau protein in her study of Protein structure.
Her Molecular dynamics research is multidisciplinary, relying on both Crystallography, Mutant and Peptide. Her Computational biology research is multidisciplinary, incorporating perspectives in Cancer, Genomics, Artificial intelligence, Protein–protein interaction and Drug discovery. Ruth Nussinov combines subjects such as Function, Antibody, Conformational change, GTP' and Binding site with her study of Allosteric regulation.
Biophysics, Cell biology, Biochemistry, Membrane and PI3K/AKT/mTOR pathway are her primary areas of study. The concepts of her Biophysics study are interwoven with issues in Protein structure, Mitochondrion and Permeation. Ruth Nussinov conducts interdisciplinary study in the fields of Protein structure and Polygene through her research.
Her Cell biology study combines topics from a wide range of disciplines, such as Ubiquitin ligase complex, Ubiquitin, Allosteric regulation and Drug discovery. Her research in Membrane intersects with topics in Transport protein and Molecular dynamics. Her PI3K/AKT/mTOR pathway research incorporates themes from Protein kinase B, Calmodulin, MAPK/ERK pathway and Effector.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
PatchDock and SymmDock: servers for rigid and symmetric docking
Dina Schneidman-Duhovny;Yuval Inbar;Ruth Nussinov;Haim J. Wolfson.
Nucleic Acids Research (2005)
The role of dynamic conformational ensembles in biomolecular recognition
David D Boehr;Ruth Nussinov;Ruth Nussinov;Peter E Wright.
Nature Chemical Biology (2009)
Principles of docking: An overview of search algorithms and a guide to scoring functions
Inbal Halperin;Buyong Ma;Haim Wolfson;Ruth Nussinov;Ruth Nussinov.
Is allostery an intrinsic property of all dynamic proteins
K. Gunasekaran;Buyong Ma;Ruth Nussinov;Ruth Nussinov.
Factors enhancing protein thermostability
Sandeep Kumar;Chung-Jung Tsai;Ruth Nussinov.
Protein Engineering (2000)
Algorithms for Loop Matchings
Ruth Nussinov;George Pieczenik;Jerrold R. Griggs;Daniel J. Kleitman.
Siam Journal on Applied Mathematics (1978)
FOLDING FUNNELS, BINDING FUNNELS, AND PROTEIN FUNCTION
Chung-Jung Tsai;Sandeep Kumar;Buyong Ma;Ruth Nussinov;Ruth Nussinov.
Protein Science (1999)
Efficient Unbound Docking of Rigid Molecules
Dina Duhovny;Ruth Nussinov;Haim J. Wolfson.
workshop on algorithms in bioinformatics (2002)
Fast algorithm for predicting the secondary structure of single-stranded RNA
Ruth Nussinov;Ann B. Jacobson.
Proceedings of the National Academy of Sciences of the United States of America (1980)
Principles of Protein−Protein Interactions: What are the Preferred Ways For Proteins To Interact?
Ozlem Keskin;Attila Gursoy;Buyong Ma;Ruth Nussinov.
Chemical Reviews (2008)
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