What is she best known for?
The fields of study she is best known for:
Ruth Nussinov mainly focuses on Protein structure, Crystallography, Protein folding, Biophysics and Docking.
Her Protein structure research includes themes of Plasma protein binding, Allosteric regulation and Binding site.
The various areas that Ruth Nussinov examines in her Crystallography study include Hydrophobic effect, Salt bridge, Hydrogen bond and Protein–protein interaction.
Ruth Nussinov works mostly in the field of Protein folding, limiting it down to topics relating to Chemical physics and, in certain cases, Molecular dynamics.
Her study in Biophysics is interdisciplinary in nature, drawing from both Hydrophobic collapse, Peptide and Amyloid.
The study incorporates disciplines such as Algorithm and Hinge in addition to Docking.
Her most cited work include:
- PatchDock and SymmDock: servers for rigid and symmetric docking (1917 citations)
- The role of dynamic conformational ensembles in biomolecular recognition (1421 citations)
- The role of dynamic conformational ensembles in biomolecular recognition (1421 citations)
What are the main themes of her work throughout her whole career to date?
Her primary scientific interests are in Protein structure, Biophysics, Crystallography, Computational biology and Biochemistry.
Her studies deal with areas such as Plasma protein binding, Docking, Protein folding, Peptide sequence and Binding site as well as Protein structure.
Her work deals with themes such as Folding, Hydrophobic effect and Folding, which intersect with Protein folding.
In her study, Signal transduction is inextricably linked to Allosteric regulation, which falls within the broad field of Biophysics.
While the research belongs to areas of Crystallography, Ruth Nussinov spends her time largely on the problem of Molecular dynamics, intersecting her research to questions surrounding Stereochemistry.
Her Computational biology research includes elements of Genetics, Function, Protein–protein interaction and Bioinformatics, Drug discovery.
She most often published in these fields:
- Protein structure (45.32%)
- Biophysics (35.62%)
- Crystallography (35.79%)
What were the highlights of her more recent work (between 2016-2022)?
- Biophysics (35.62%)
- Cell biology (17.08%)
- Computational biology (30.90%)
In recent papers she was focusing on the following fields of study:
The scientist’s investigation covers issues in Biophysics, Cell biology, Computational biology, Allosteric regulation and PI3K/AKT/mTOR pathway.
Her Biophysics research integrates issues from Protein structure, Membrane, Biochemistry and Molecular dynamics.
Her research integrates issues of Enzyme activator, Protein domain and Tau protein in her study of Protein structure.
Her Molecular dynamics research is multidisciplinary, relying on both Crystallography, Mutant and Peptide.
Her Computational biology research is multidisciplinary, incorporating perspectives in Cancer, Genomics, Artificial intelligence, Protein–protein interaction and Drug discovery.
Ruth Nussinov combines subjects such as Function, Antibody, Conformational change, GTP' and Binding site with her study of Allosteric regulation.
Between 2016 and 2022, her most popular works were:
- deepDR: a network-based deep learning approach to in silico drug repositioning. (149 citations)
- Allostery in Its Many Disguises: From Theory to Applications (129 citations)
- Artificial intelligence in COVID-19 drug repurposing. (127 citations)
In her most recent research, the most cited papers focused on:
Biophysics, Cell biology, Biochemistry, Membrane and PI3K/AKT/mTOR pathway are her primary areas of study.
The concepts of her Biophysics study are interwoven with issues in Protein structure, Mitochondrion and Permeation.
Ruth Nussinov conducts interdisciplinary study in the fields of Protein structure and Polygene through her research.
Her Cell biology study combines topics from a wide range of disciplines, such as Ubiquitin ligase complex, Ubiquitin, Allosteric regulation and Drug discovery.
Her research in Membrane intersects with topics in Transport protein and Molecular dynamics.
Her PI3K/AKT/mTOR pathway research incorporates themes from Protein kinase B, Calmodulin, MAPK/ERK pathway and Effector.
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