D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 58 Citations 13,475 379 World Ranking 8795 National Ranking 35

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Amino acid

The scientist’s investigation covers issues in Biochemistry, Stereochemistry, Protein structure, Peptide sequence and Biophysics. In his study, Drug resistance, Microbiology and Xanthone is inextricably linked to Bacteria, which falls within the broad field of Biochemistry. His Protein structure study incorporates themes from Binding site and Cell biology.

His study focuses on the intersection of Peptide sequence and fields such as Peptide with connections in the field of Combinatorial chemistry and Phosphorylation. His work carried out in the field of Biophysics brings together such families of science as Plasma protein binding, Nanotechnology, Adhesive and Molecular dynamics. Chandra S. Verma studied Molecular dynamics and Transcription factor that intersect with Mutant, Mdm2, Cancer, Drug development and Drug discovery.

His most cited work include:

  • Awakening guardian angels: drugging the p53 pathway (674 citations)
  • Drugging the p53 pathway: understanding the route to clinical efficacy (503 citations)
  • Drugging the p53 pathway: understanding the route to clinical efficacy (503 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Biochemistry, Biophysics, Peptide, Stereochemistry and Cell biology. Binding site, Plasma protein binding, Protein–protein interaction and Small molecule are among the areas of Biochemistry where the researcher is concentrating his efforts. Chandra S. Verma has researched Biophysics in several fields, including Molecular dynamics, Mutant, Membrane, Lipid bilayer and Protein structure.

Chandra S. Verma interconnects Mutation, DNA-binding domain and Cancer research in the investigation of issues within Mutant. His research in Peptide intersects with topics in Amino acid, Peptide sequence, Computational biology and Mdm2. His Cell biology research includes elements of Molecular biology and Transcription factor.

He most often published in these fields:

  • Biochemistry (50.32%)
  • Biophysics (52.05%)
  • Peptide (38.33%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cell biology (36.28%)
  • Biophysics (52.05%)
  • Cancer research (20.82%)

In recent papers he was focusing on the following fields of study:

Chandra S. Verma spends much of his time researching Cell biology, Biophysics, Cancer research, Peptide and Computational biology. His research integrates issues of Cleavage, Mutant and Binding site in his study of Cell biology. Chandra S. Verma combines subjects such as Molecular dynamics, Mutation, Membrane, Lipid bilayer and Molecule with his study of Biophysics.

His Cancer research research is multidisciplinary, relying on both Bladder cancer, Cancer, Receptor, Kinase and Ubiquitin ligase. His Peptide research is multidisciplinary, incorporating perspectives in Amino acid, Cancer cell, Stereochemistry, Small molecule and Intracellular. His Computational biology research incorporates elements of Eukaryotic translation, Binding affinities, Protein–protein interaction, EIF4E and Drug discovery.

Between 2017 and 2021, his most popular works were:

  • Macrocyclic α helical peptide therapeutic modality: A perspective of learnings and challenges (25 citations)
  • Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide (21 citations)
  • Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide (21 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Amino acid

The scientist’s investigation covers issues in Peptide, Cell biology, Small molecule, Computational biology and Biophysics. The various areas that he examines in his Peptide study include Ligand, Cancer cell, Mdm2 and Stereochemistry, Circular dichroism. His Mdm2 study combines topics in areas such as Phosphorylation and Stapled peptide.

His work on Mitochondrion as part of general Cell biology research is frequently linked to Protein glutathionylation, bridging the gap between disciplines. His Small molecule research incorporates themes from Platelet, Unfolded protein response, Allosteric regulation, Binding site and Drug discovery. His studies deal with areas such as Mutation, Lipid bilayer and Druggability as well as Biophysics.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Awakening guardian angels: drugging the p53 pathway

Christopher J. Brown;Sonia Lain;Chandra S. Verma;Alan R. Fersht.
Nature Reviews Cancer (2009)

1005 Citations

Drugging the p53 pathway: understanding the route to clinical efficacy

Kian Hoe Khoo;Chandra S. Verma;Chandra S. Verma;Chandra S. Verma;David P. Lane.
Nature Reviews Drug Discovery (2014)

770 Citations

Lapatinib, a HER2 tyrosine kinase inhibitor, induces stabilization and accumulation of HER2 and potentiates trastuzumab-dependent cell cytotoxicity

M Scaltriti;C Verma;M Guzman;J Jimenez.
Oncogene (2009)

411 Citations

Translating p53 into the clinic

Chit Fang Cheok;Chandra S Verma;José Baselga;David P Lane.
Nature Reviews Clinical Oncology (2011)

393 Citations

The crystal structure of the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia at 1.7 A resolution.

J.H. Ullah;T.R. Walsh;T.R. Walsh;I.A. Taylor;D.C. Emery.
Journal of Molecular Biology (1998)

376 Citations

Structural origins of the interfacial activation in Thermomyces (Humicola) lanuginosa lipase.

A M Brzozowski;H Savage;C S Verma;J P Turkenburg.
Biochemistry (2000)

253 Citations

Membrane Active Antimicrobial Peptides: Translating Mechanistic Insights to Design.

Jianguo Li;Jianguo Li;Jun-Jie Koh;Shouping Liu;Rajamani Lakshminarayanan.
Frontiers in Neuroscience (2017)

235 Citations

Stapled Peptides with Improved Potency and Specificity That Activate p53

Christopher J. Brown;Soo T. Quah;Janice Jong;Amanda M. Goh.
ACS Chemical Biology (2013)

204 Citations

The Crystal Structure of the Globular Domain of Sheep Prion Protein

L.F. Haire;S.M. Whyte;N. Vasisht;Andrew C. Gill.
Journal of Molecular Biology (2004)

196 Citations

Erratum: Drugging the p53 pathway: understanding the route to clinical efficacy

Kian Hoe Khoo;Chandra S. Verma;David P. Lane.
Nature Reviews Drug Discovery (2014)

174 Citations

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