Chandra S. Verma

Overview

Best Publications

• Awakening guardian angels: drugging the p53 pathway

  Christopher J. Brown;Sonia Lain;Chandra S. Verma;Alan R. Fersht

  1148
  Citations

• Drugging the p53 pathway: understanding the route to clinical efficacy

  Kian Hoe Khoo;Chandra S. Verma;Chandra S. Verma;Chandra S. Verma;David P. Lane

  833
  Citations

• Membrane Active Antimicrobial Peptides: Translating Mechanistic Insights to Design.

  Jianguo Li;Jianguo Li;Jun-Jie Koh;Shouping Liu;Rajamani Lakshminarayanan

  531
  Citations

• Lapatinib, a HER2 tyrosine kinase inhibitor, induces stabilization and accumulation of HER2 and potentiates trastuzumab-dependent cell cytotoxicity

  M Scaltriti;C Verma;M Guzman;J Jimenez

  497
  Citations

• Translating p53 into the clinic

  Chit Fang Cheok;Chandra S Verma;José Baselga;David P Lane

  441
  Citations

• The crystal structure of the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia at 1.7 A resolution.

  J.H. Ullah;T.R. Walsh;T.R. Walsh;I.A. Taylor;D.C. Emery

  417
  Citations

• Structural origins of the interfacial activation in Thermomyces (Humicola) lanuginosa lipase.

  A M Brzozowski;H Savage;C S Verma;J P Turkenburg

  298
  Citations

• Stapled Peptides with Improved Potency and Specificity That Activate p53

  Christopher J. Brown;Soo T. Quah;Janice Jong;Amanda M. Goh

  235
  Citations

• PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition

  Pau Castel;Haley Ellis;Ruzica Bago;Eneda Toska

  218
  Citations

• Rapid bactericidal action of alpha-mangostin against MRSA as an outcome of membrane targeting.

  Jun-Jie Koh;Shengxiang Qiu;Hanxun Zou;Rajamani Lakshminarayanan

  211
  Citations

• Functionalised staple linkages for modulating the cellular activity of stapled peptides

  Yu Heng Lau;Peterson De Andrade;Soo Tng Quah;Maxim Rossmann

  205
  Citations

• The Crystal Structure of the Globular Domain of Sheep Prion Protein

  L.F. Haire;S.M. Whyte;N. Vasisht;Andrew C. Gill

  199
  Citations

• Mussel adhesion is dictated by time-regulated secretion and molecular conformation of mussel adhesive proteins

  Luigi Petrone;Akshita Kumar;Clarinda N. Sutanto;Navinkumar J. Patil

  194
  Citations

• Defensins knowledgebase: a manually curated database and information source focused on the defensins family of antimicrobial peptides

  Shalin Seebah;Anita Suresh;Shaowei Zhuo;Yong How Choong

  183
  Citations

• Molecular simulations of protein dynamics: new windows on mechanisms in biology

  Guy G Dodson;Guy G Dodson;David P Lane;Chandra S Verma

  179
  Citations

• Multiple self-healing squamous epithelioma is caused by a disease-specific spectrum of mutations in TGFBR1

  David R Goudie;Mariella D'Alessandro;Barry Merriman;Hane Lee

  177
  Citations

• Erratum: Drugging the p53 pathway: understanding the route to clinical efficacy

  Kian Hoe Khoo;Chandra S. Verma;David P. Lane

  177
  Citations

• Prion and water: Tight and dynamical hydration sites have a key role in structural stability

  Alfonso De Simone;Guy G. Dodson;Chandra S. Verma;Adriana Zagari

  176
  Citations

• A comparison and optimization of methods and factors affecting the transformation of Escherichia coli

  Weng‑Tat Chan;Chandra S. Verma;Chandra S. Verma;Chandra S. Verma;David P. Lane;David P. Lane;Samuel Ken‑En Gan

  165
  Citations

• The crystal structure of the AAA domain of the ATP-dependent protease FtsH of Escherichia coli at 1.5 A resolution.

  Szymon Krzywda;Andrzej M. Brzozowski;Chandra Verma;Kiyonobu Karata

  164
  Citations