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D-Index
69
Citations
30484
World Ranking
6071
National Ranking
26

Overview

Alexander Dömling is a researcher affiliated with Palacký University, Olomouc in Czech Republic. Their work spans multiple disciplines, chiefly focusing on biochemistry, genetics, molecular biology, chemistry, and medicine. Their research interests are further detailed in specialized subfields such as organic chemistry, molecular biology, materials chemistry, oncology, and physiology.

The scientist's research topics include crystallization and solubility studies, X-ray diffraction in crystallography, chemical synthesis and analysis, multicomponent synthesis of heterocycles, synthesis and biological activity, computational drug discovery methods, and click chemistry applications.

Some notable recent publications by Alexander Dömling include:

  • Chemistry and Biology of SARS-CoV-2, 2020, Chem

Alexander Dömling has collaborated frequently with other researchers, among them:

  • Katarzyna Kurpiewska
  • Shabnam Shaabani
  • Constantinos G. Neochoritis
  • Matthew R. Groves
  • Justyna Kalinowska-Tłuścik

Their research has been published predominantly in several venues, including:

  • University of Groningen research database (University of Groningen / Centre for Information Technology)
  • The Journal of Organic Chemistry
  • Green Chemistry
  • ChemMedChem
  • Molecules

Best Publications

  • Multicomponent Reactions with Isocyanides.

    Alexander Dömling;Ivar Ugi

  • Recent developments in isocyanide based multicomponent reactions in applied chemistry

    Alexander Dömling

  • Chemistry and Biology Of Multicomponent Reactions

    Alexander Dömling;Wei Wang;Wei Wang;Kan Wang

  • MULTICOMPONENT REACTIONS IN ORGANIC-CHEMISTRY

    Ivar Ugi;Alexander Dömling;Werner Hörl

  • Recent advances in isocyanide-based multicomponent chemistry

    Alexander Dömling

  • The Chemistry of Isocyanides, their MultiComponent Reactions and their Libraries

    I. Ugi;B. Werner;A. Dömling

  • Tetrazoles via Multicomponent Reactions.

    Constantinos G. Neochoritis;Ting Zhao;Alexander Dömling

  • Multikomponentenreaktionen mit Isocyaniden

    Alexander Dömling;Ivar Ugi

  • Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)

    Krzysztof M. Zak;Przemyslaw Grudnik;Katarzyna Guzik;Bartosz J. Zieba

  • Structural Biology of the Immune Checkpoint Receptor PD-1 and Its Ligands PD-L1/PD-L2

    Krzysztof M. Zak;Przemyslaw Grudnik;Katarzyna Magiera;Alexander Dömling

  • Covalent inhibitors: A rational approach to drug discovery

    Fandi Sutanto;Markella Konstantinidou;Alexander Dömling

  • Since 1995 the new chemistry of multicomponent reactions and their libraries, including their heterocyclic chemistry

    Ivar Ugi;Alexander Domling;Birgit Werner

  • Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Death-Ligand 1 (PD-1/PD-L1) Interaction via Transiently Induced Protein States and Dimerization of PD-L1

    Katarzyna Guzik;Krzysztof M. Zak;Przemyslaw Grudnik;Katarzyna Magiera

  • Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells

    Lukasz Skalniak;Krzysztof M Zak;Katarzyna Guzik;Katarzyna Magiera

  • Multicomponent Reactions, Union of MCRs and Beyond

    Tryfon Zarganes-Tzitzikas;Ajay L. Chandgude;Alexander Dömling

  • Structures of low molecular weight inhibitors bound to MDMX and MDM2 reveal new approaches for p53-MDMX/MDM2 antagonist drug discovery

    Grzegorz M Popowicz;Anna Czarna;Siglinde Wolf;Kan Wang

  • The discovery of new isocyanide-based multi-component reactions.

    Alexander Dömling

  • Isocyanide based multi component reactions in combinatorial chemistry.

    A. Dömling

  • The Gewald multicomponent reaction.

    Yijun Huang;Alexander Dömling

  • Biological evaluation of tubulysin A: a potential anticancer and antiangiogenic natural product.

    Gurmeet Kaur;Melinda Hollingshead;Susan Holbeck;Vesna Schauer-Vukašinović

Frequent Co-Authors

Tad A. Holak
Tad A. Holak Jagiellonian University
Ivar Ugi
Ivar Ugi Technical University of Munich
Eberhardt Herdtweck
Eberhardt Herdtweck Technical University of Munich
Ludger A. Wessjohann
Ludger A. Wessjohann Leibniz Association
Reinoud Gosens
Reinoud Gosens University of Groningen
Christopher Hulme
Christopher Hulme University of Arizona
Jeffrey L. Brodsky
Jeffrey L. Brodsky University of Pittsburgh
Yuan Chang
Yuan Chang University of Pittsburgh
Jan Potempa
Jan Potempa University of Louisville
Hidde J. Haisma
Hidde J. Haisma University of Groningen

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