2026 Jeffrey L. Brodsky: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	84	3242	2982	1641	1473	326	37855

Research.com Recognitions

2013 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Jeffrey L. Brodsky is affiliated with the University of Pittsburgh in the United States and works primarily within the fields of Biochemistry, Genetics, and Molecular Biology, with a substantial focus on Medicine. Their research spans several interconnected subfields, including Molecular Biology, Cell Biology, Epidemiology, Surgery, and Immunology.

The main topics of Jeffrey L. Brodsky's research include:

Endoplasmic Reticulum Stress and Disease
Heat shock proteins research
Autophagy in Disease and Therapy
Cellular transport and secretion
Ion Transport and Channel Regulation
Pancreatic function and diabetes
Ion channel regulation and function

Frequent publication venues for their work include:

bioRxiv (Cold Spring Harbor Laboratory)
The FASEB Journal
Molecular Biology of the Cell
Cancer Research
American Journal of Physiology-Cell Physiology

Jeffrey L. Brodsky has collaborated regularly with several coauthors, such as:

Teresa M. Buck
Christopher J. Guerriero
Sara Sannino
Peter Wipf
Thomas R. Kleyman

Notable recent papers include:

"ER-Phagy, ER Homeostasis, and ER Quality Control: Implications for Disease" (2021) published in Trends in Biochemical Sciences
"Regulation of CFTR Biogenesis by the Proteostatic Network and Pharmacological Modulators" (2020) in International Journal of Molecular Sciences
"The Essential Functions of Molecular Chaperones and Folding Enzymes in Maintaining Endoplasmic Reticulum Homeostasis" (2023) in Journal of Molecular Biology
"The Targeting of Native Proteins to the Endoplasmic Reticulum-Associated Degradation (ERAD) Pathway: An Expanding Repertoire of Regulated Substrates" (2021) published in Biomolecules
"Unique integrated stress response sensors regulate cancer cell susceptibility when Hsp70 activity is compromised" (2021) published in eLife

In 2013, Jeffrey L. Brodsky received the distinction of Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

10661
Citations
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

2934
Citations
One step at a time: endoplasmic reticulum-associated degradation

Shruthi S. Vembar;Jeffrey L. Brodsky

1805
Citations
Proteasome-dependent endoplasmic reticulum-associated protein degradation: An unconventional route to a familiar fate

Eric D. Werner;Jeffrey L. Brodsky;Ardythe A. McCracken

635
Citations
From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations.

Gudio Veit;Radu G. Avramescu;Annette N. Chiang;Scott A. Houck

559
Citations
ER protein quality control and proteasome-mediated protein degradation.

Jeffrey L. Brodsky;Ardythe A. McCracken;Ardythe A. McCracken

506
Citations
Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation

Shuh-ichi Nishikawa;Sheara W. Fewell;Yoshihito Kato;Jeffrey L. Brodsky

464
Citations
Cleaning Up: ER-Associated Degradation to the Rescue

Jeffrey L. Brodsky

460
Citations
RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43.

Jacob R. Mann;Amanda M. Gleixner;Jocelyn C. Mauna;Edward Gomes

441
Citations
The Delicate Balance Between Secreted Protein Folding and Endoplasmic Reticulum-Associated Degradation in Human Physiology

Christopher J. Guerriero;Jeffrey L. Brodsky

429
Citations
The Action of Molecular Chaperones in the Early Secretory Pathway

Sheara W. Fewell;Kevin J. Travers;Jonathan S. Weissman;Jeffrey L. Brodsky

411
Citations
The Requirement for Molecular Chaperones during Endoplasmic Reticulum-associated Protein Degradation Demonstrates That Protein Export and Import Are Mechanistically Distinct

Jeffrey L. Brodsky;Eric D. Werner;Maria E. Dubas;Jennifer L. Goeckeler

407
Citations
A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome.

J L Brodsky;R Schekman

407
Citations
The recognition and retrotranslocation of misfolded proteins from the endoplasmic reticulum.

Kunio Nakatsukasa;Jeffrey L. Brodsky

391
Citations
BiP and Sec63p are required for both co- and posttranslational protein translocation into the yeast endoplasmic reticulum

Jeffrey L. Brodsky;Jennifer Goeckeler;Randy Schekman

359
Citations
Protein quality control in the secretory pathway

Zhihao Sun;Jeffrey L. Brodsky

353
Citations
A Stress-Responsive System for Mitochondrial Protein Degradation

Jin Mi Heo;Nurit Livnat-Levanon;Eric B. Taylor;Kevin T. Jones

340
Citations
Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein.

Gregory Huyer;Wachirapon F. Piluek;Zoya Fansler;Stefan G. Kreft

332
Citations
Hsp70 Molecular Chaperone Facilitates Endoplasmic Reticulum-associated Protein Degradation of Cystic Fibrosis Transmembrane Conductance Regulator in Yeast

Yimao Zhang;Gaby Nijbroek;Mara L. Sullivan;Ardythe A. McCracken

324
Citations
Dissecting the ER-Associated Degradation of a Misfolded Polytopic Membrane Protein

Kunio Nakatsukasa;Gregory Huyer;Susan Michaelis;Jeffrey L. Brodsky

315
Citations