World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
63
Citations
12884
World Ranking
8511
National Ranking
2442

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Mark L. Zeidel is affiliated with Harvard Medical School in the United States. Their research primarily centers on medicine, with significant contributions in biochemistry, genetics, and molecular biology. Their work extends across related subfields including molecular biology, urology, physiology, public health, environmental and occupational health, and neurology.

The scientist's recent publications reveal diverse interests and investigation topics. Notable papers include Dietary restriction impacts health and lifespan of genetically diverse mice (2024, Nature), Cis P-tau underlies vascular contribution to cognitive impairment and dementia and can be effectively targeted by immunotherapy in mice (2021, Science Translational Medicine), Disruption of Cav1.2-mediated signaling is a pathway for ketamine-induced pathology (2020, Nature Communications), Niacinamide May Be Associated with Improved Outcomes in COVID-19-Related Acute Kidney Injury: An Observational Study (2020, Kidney360), and A spatially-resolved transcriptional atlas of the murine dorsal pons at single-cell resolution (2024, Nature Communications).

Research topics frequently addressed in their work include:

  • Urinary bladder and prostate research
  • Neuroinflammation and neurodegeneration mechanisms
  • Pelvic floor disorders treatments
  • Dietary effects on health
  • Genetics, aging, and longevity in model organisms
  • Single-cell and spatial transcriptomics
  • COVID-19 clinical research studies

Collaborations form a significant part of their research approach, with frequent co-authors including Warren G. Hill, Weiqun Yu, Huan Chen, Bryce MacIver, and Gary A. Churchill. These partnerships have contributed to the interdisciplinary breadth seen in their publications.

The most frequent venues for Mark L. Zeidel's publications reflect the scientific disciplines they engage with, including bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Kidney360, The FASEB Journal, and the Journal of the American Society of Nephrology.

Mark L. Zeidel has been recognized as a member of the Association of American Physicians, indicating a standing within the medical research community. Their work encompasses extensive investigations at molecular and clinical levels, often focusing on translational aspects linked to health, disease mechanisms, and potential therapeutic approaches.

Best Publications

  • Diverse biological actions of atrial natriuretic peptide.

    B. M. Brenner;B. J. Ballermann;M. E. Gunning;M. L. Zeidel

  • Reconstitution of functional water channels in liposomes containing purified red cell CHIP28 protein.

    Mark L. Zeidel;Suresh V. Ambudkar;Barbara L. Smith;Peter Agre

  • A simple comorbidity scale predicts clinical outcomes and costs in dialysis patients

    Srinivasan Beddhu;Frank J Bruns;Melissa Saul;Patricia Seddon

  • The relationship between membrane fluidity and permeabilities to water, solutes, ammonia, and protons.

    M B Lande;J M Donovan;M L Zeidel

  • Structural determinants of water permeability through the lipid membrane.

    John C. Mathai;Stephanie Tristram-Nagle;John F. Nagle;Mark L. Zeidel

  • No facilitator required for membrane transport of hydrogen sulfide.

    John C. Mathai;Andreas Missner;Philipp Kügler;Philipp Kügler;Sapar M. Saparov

  • Mutations in aquaporin-1 in phenotypically normal humans without functional CHIP water channels.

    Gregory M. Preston;Barbara L. Smith;Mark L. Zeidel;John J. Moulds

  • Endothelin, a peptide inhibitor of Na(+)-K(+)-ATPase in intact renaltubular epithelial cells.

    M. L. Zeidel;H. R. Brady;B. C. Kone;S. R. Gullans

  • Ultrastructure, pharmacologic inhibition, and transport selectivity of aquaporin channel-forming integral protein in proteoliposomes.

    Mark L. Zeidel;Soren Nielsen;Soren Nielsen;Soren Nielsen;Barbara L. Smith;Barbara L. Smith;Barbara L. Smith;Suresh V. Ambudkar;Suresh V. Ambudkar;Suresh V. Ambudkar

  • Role of membrane proteins in permeability barrier function: uroplakin ablation elevates urothelial permeability

    Ping Hu;Susan Meyers;Feng-Xia Liang;Fang-Ming Deng

  • Permeability properties of the intact mammalian bladder epithelium

    H. O. Negrete;J. P. Lavelle;J. Berg;S. A. Lewis

  • Symptom burden, quality of life, advance care planning and the potential value of palliative care in severely ill haemodialysis patients

    Steven D. Weisbord;Sharon S. Carmody;Frank J. Bruns;Armando J. Rotondi

  • Biologically active two-dimensional crystals of aquaporin CHIP

    T Walz;B L Smith;M L Zeidel;A Engel

  • Stretch-regulated Exocytosis/Endocytosis in Bladder Umbrella Cells

    Steven T. Truschel;Edward Wang;Wily G. Ruiz;Som-Ming Leung

  • Cell membranes impermeable to NH3.

    Deepak Kikeri;Adam Sun;Mark L. Zeidel;Steven C. Hebert

  • Purification and functional reconstitution of soybean nodulin 26. An aquaporin with water and glycerol transport properties

    Robert M. Dean;Ricky L. Rivers;Mark L. Zeidel;Daniel M. Roberts

  • Functional Analysis of Nodulin 26, an Aquaporin in Soybean Root Nodule Symbiosomes

    Rickey L. Rivers;Robert M. Dean;Grischa Chandy;James E. Hall

  • Bladder permeability barrier: recovery from selective injury of surface epithelial cells

    John Lavelle;Susan Meyers;Richard Ramage;Sheldon Bastacky

  • Reconstituted aquaporin 1 water channels transport CO2 across membranes.

    G. V. Ramesh Prasad;Larry A. Coury;Frances Finn;Mark L. Zeidel

  • Molecular Mechanisms of Water and Solute Transport across Archaebacterial Lipid Membranes

    John C. Mathai;G. Dennis Sprott;Mark L. Zeidel

  • Atrial natriuretic peptides inhibit conductive sodium uptake by rabbit inner medullary collecting duct cells.

    M L Zeidel;D Kikeri;P Silva;M Burrowes

  • Mitochondrial injury: an early event in cisplatin toxicity to renal proximal tubules.

    Hugh R. Brady;Bruce C Kone;Michael E. Stromski;Mark L. Zeidel

  • Carbon Dioxide Transport through Membranes

    Andreas Missner;Philipp Kügler;Sapar M. Saparov;Klaus Sommer

Frequent Co-Authors

Gerard Apodaca
Gerard Apodaca University of Pittsburgh
Barry M. Brenner
Barry M. Brenner Brigham and Women's Hospital
Peter Agre
Peter Agre Johns Hopkins University
Timothy G. Hammond
Timothy G. Hammond Veterans Health Administration
Jeffrey L. Brodsky
Jeffrey L. Brodsky University of Pittsburgh
Peter Pohl
Peter Pohl Johannes Kepler University of Linz
Steven C. Hebert
Steven C. Hebert Yale University
Tung-Tien Sun
Tung-Tien Sun New York University
Stephanie Tristram-Nagle
Stephanie Tristram-Nagle Carnegie Mellon University
Suresh V. Ambudkar
Suresh V. Ambudkar National Institutes of Health

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