World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
120
Citations
53079
World Ranking
3755
National Ranking
2066

Overview

Mark A. Knepper is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a significant emphasis on medicine. The main subfields of their work include molecular biology, pulmonary and respiratory medicine, nephrology, social psychology, and surgery.

The scientist's research topics cover diverse areas, including:

  • Ion transport and channel regulation
  • Renal and related cancers
  • Electrolyte and hormonal disorders
  • Neuroendocrine regulation and behavior
  • Pancreatic function and diabetes
  • Chronic kidney disease and diabetes
  • Birth, development, and health

Mark A. Knepper has contributed extensively to academic literature, with notable recent papers including:

  • "Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles," 2021, Journal of Extracellular Vesicles
  • "A Comprehensive Map of mRNAs and Their Isoforms across All 14 Renal Tubule Segments of Mouse," 2021, Journal of the American Society of Nephrology
  • "Quantitative Proteomics of All 14 Renal Tubule Segments in Rat," 2020, Journal of the American Society of Nephrology
  • "Targeted Single-Cell RNA-seq Identifies Minority Cell Types of Kidney Distal Nephron," 2021, Journal of the American Society of Nephrology
  • "Transcriptomes of Major Proximal Tubule Cell Culture Models," 2020, Journal of the American Society of Nephrology

The scientist frequently publishes in several prominent venues, including:

  • Journal of the American Society of Nephrology
  • American Journal of Physiology-Renal Physiology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Physiology
  • The FASEB Journal

Collaboration is an integral part of their work. Regular co-authors include Lihe Chen, Chung-Lin Chou, Viswanathan Raghuram, Chin-Rang Yang, and Euijung Park, with numerous joint publications.

Best Publications

  • Aquaporins in the Kidney: From Molecules to Medicine

    Søren Nielsen;Jørgen Frøkiær;David Marples;Tae Hwan Kwon

  • Vasopressin increases water permeability of kidney collecting duct by inducing translocation of aquaporin-CD water channels to plasma membrane

    Søren Nielsen;Chung Lin Chou;David Marples;Erik I. Christensen

  • Aldosterone-mediated regulation of ENaC α, β, and γ subunit proteins in rat kidney

    Shyama Masilamani;Gheun-Ho Kim;Carter Mitchell;James B. Wade

  • Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes

    Patricia A. Gonzales;Trairak Pisitkun;Jason D. Hoffert;Dmitry Tchapyjnikov

  • Collection, storage, preservation, and normalization of human urinary exosomes for biomarker discovery

    Hua Zhou;Peter S.T. Yuen;Trairak Pisitkun;Patricia A. Gonzales

  • Deep Sequencing in Microdissected Renal Tubules Identifies Nephron Segment–Specific Transcriptomes

    Jae Wook Lee;Chung-Lin Chou;Mark A. Knepper

  • Defective proximal tubular fluid reabsorption in transgenic aquaporin-1 null mice

    Jurgen Schnermann;Chung Lin Chou;Tonghui Ma;Timothy Traynor

  • Epilepsy, ataxia, sensorineural deafness, tubulopathy, and KCNJ10 mutations.

    Detlef Bockenhauer;Sally Feather;Horia C Stanescu;Sascha Bandulik

  • Pendrin, encoded by the Pendred syndrome gene, resides in the apical region of renal intercalated cells and mediates bicarbonate secretion

    Ines E. Royaux;Susan M. Wall;Lawrence P. Karniski;Lorraine A. Everett

  • Regulation of collecting duct water channel expression by vasopressin in Brattleboro rat

    Susan R. Digiovanni;Soren Nielsen;Erik Ilso Christensen;Mark A. Knepper

  • Rapid isolation of urinary exosomal biomarkers using a nanomembrane ultrafiltration concentrator.

    Anita Cheruvanky;Hua Zhou;Trairak Pisitkun;Jeffrey B. Kopp

  • Aquaporin-3 water channel localization and regulation in rat kidney

    C A Ecelbarger;J Terris;G Frindt;M Echevarria

  • Exosomal Fetuin-A identified by proteomics: a novel urinary biomarker for detecting acute kidney injury.

    Hua Zhou;Trairak Pisitkun;Angel Aponte;Peter S.T. Yuen

  • Discovery of Urinary Biomarkers

    Trairak Pisitkun;Rose Johnstone;Mark A. Knepper

  • Long-term regulation of four renal aquaporins in rats

    J. Terris;C. A. Ecelbarger;S. Nielsen;M. A. Knepper

  • The thiazide-sensitive Na–Cl cotransporter is an aldosterone-induced protein

    Gheun-Ho Kim;Shyama Masilamani;Rachel Turner;Carter Mitchell

  • Redistribution of aquaporin-2 water channels induced by vasopressin in rat kidney inner medullary collecting duct.

    D. Marples;M. A. Knepper;E. I. Christensen;S. Nielsen

  • Control of sodium and potassium transport in the cortical collecting duct of the rat. Effects of bradykinin, vasopressin, and deoxycorticosterone.

    Kimio Tomita;John J. Pisano;Mark A. Knepper

  • Quantitative phosphoproteomics of vasopressin-sensitive renal cells: Regulation of aquaporin-2 phosphorylation at two sites

    Jason D. Hoffert;Trairak Pisitkun;Guanghui Wang;Rong-Fong Shen

  • Molecular physiology of urinary concentrating mechanism: regulation of aquaporin water channels by vasopressin.

    M. A. Knepper

Frequent Co-Authors

Trairak Pisitkun
Trairak Pisitkun Chulalongkorn University
Søren Nielsen
Søren Nielsen Aalborg University
Jørgen Frøkiær
Jørgen Frøkiær Aarhus University
Tae-Hwan Kwon
Tae-Hwan Kwon Kyungpook National University
Maurice B. Burg
Maurice B. Burg National Institutes of Health
Joseph G. Verbalis
Joseph G. Verbalis Georgetown University Medical Center
Robert A. Star
Robert A. Star National Institutes of Health
Peter Agre
Peter Agre Johns Hopkins University
Dennis Brown
Dennis Brown Harvard University
Sylvie Breton
Sylvie Breton Harvard University

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