World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
122
Citations
48988
World Ranking
587
National Ranking
376

Medicine

D-Index
121
Citations
48085
World Ranking
3634
National Ranking
2006

Overview

Dennis Brown is affiliated with Harvard University in the United States. Their research encompasses a range of topics within biochemistry, genetics, molecular biology, and medicine, with significant contributions to several subfields and main topics of study.

Their main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, Dennis Brown has focused extensively on subfields such as:

  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Oncology
  • Immunology
  • Genetics

The main topics of research covered by their publications include:

  • Ion Transport and Channel Regulation
  • ATP Synthase and ATPases Research
  • Renal and related cancers
  • Glioma Diagnosis and Treatment
  • Electrolyte and hormonal disorders
  • Cancer therapeutics and mechanisms
  • PARP inhibition in cancer therapy

Dennis Brown has published extensively in notable journals. Frequent publication venues for their work include:

  • Cancer Research
  • Neuro-Oncology
  • American Journal of Physiology-Renal Physiology
  • IEEE Transactions on Nuclear Science
  • bioRxiv (Cold Spring Harbor Laboratory)

Their recent papers span a range of biomedical topics and were published in several high-impact journals:

  • Investigating the pharmacodynamic durability of GalNAc-siRNA conjugates, 2020, Nucleic Acids Research
  • Cerebrospinal fluid can exit into the skull bone marrow and instruct cranial hematopoiesis in mice with bacterial meningitis, 2022, Nature Neuroscience
  • The H+-ATPase (V-ATPase): from proton pump to signaling complex in health and disease, 2020, American Journal of Physiology-Cell Physiology
  • Proinflammatory P2Y14 receptor inhibition protects against ischemic acute kidney injury in mice, 2020, Journal of Clinical Investigation
  • Neutrophils incite and macrophages avert electrical storm after myocardial infarction, 2022, Nature Cardiovascular Research

The scientist frequently collaborates with a core group of coauthors, including:

  • Jeffrey Bacha
  • John Langlands
  • Richard Bouley
  • Sarath Kanekal
  • Amity F. Eaton

Dennis Brown's research contributions reflect a multidisciplinary approach, intersecting molecular biology with clinical medicine and oncology. Their work integrates mechanisms of ion transport, cellular energetics, immune response, and cancer biology, which is demonstrated through their publishing history and collaborative network.

Best Publications

  • Cellular uptake of nanoparticles: journey inside the cell.

    Shahed Behzadi;Vahid Serpooshan;Wei Tao;Majd A. Hamaly

  • TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function.

    Jochen Reiser;Krishna R Polu;Clemens C Möller;Peter Kenlan

  • Macrophages facilitate electrical conduction in the heart

    Maarten Hulsmans;Sebastian Clauss;Sebastian Clauss;Ling Xiao;Aaron D. Aguirre

  • The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose.

    Yoshikatsu Kanai;Wen Sen Lee;Guofeng You;Dennis Brown

  • Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells.

    Ralph Witzgall;Dennis Brown;Cordula Schwarz;Joseph V. Bonventre

  • In vivo molecular probing of cellular compartments with gold nanoparticles and nanoaggregates.

    Janina Kneipp;Harald Kneipp;Margaret McLaughlin;Dennis Brown

  • V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway

    Andrés Hurtado-Lorenzo;Mhairi Skinner;Jaafar El Annan;Masamitsu Futai

  • Renal Vacuolar H+-ATPase

    Carsten A. Wagner;Karin E. Finberg;Sylvie Breton;Vladimir Marshansky

  • Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease

    Kevin C. Miranda;Daniel T. Bond;Mary McKee;Johan Skog

  • Role of VEGF-A in Vascularization of Pancreatic Islets

    Eckhard Lammert;Guqiang Gu;Margaret McLaughlin;Dennis Brown

  • The normal kidney filters nephrotic levels of albumin retrieved by proximal tubule cells: Retrieval is disrupted in nephrotic states

    L.M. Russo;R.M. Sandoval;M. McKee;T.M. Osicka

  • Localization of MIWC and GLIP water channel homologs in neuromuscular, epithelial and glandular tissues

    Antonio Frigeri;Michael A. Gropper;Fuminori Umenishi;M. Kawashima

  • Subtypes of intercalated cells in rat kidney collecting duct defined by antibodies against erythroid band 3 and renal vacuolar H+-ATPase.

    S L Alper;J Natale;S Gluck;H F Lodish

  • Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance.

    Libin Liu;Dennis Brown;Mary McKee;Nathan K. LeBrasseur

  • Organ distribution in rats of two members of the low-density lipoprotein receptor gene family, gp330 and LRP/alpha 2MR, and the receptor-associated protein (RAP).

    Gang Zheng;D. R. Bachinsky;I. Stamenkovic;D. K. Strickland

  • Localization of a proton-pumping ATPase in rat kidney.

    D Brown;S Hirsch;S Gluck

  • Protein kinase A phosphorylation is involved in regulated exocytosis of aquaporin-2 in transfected LLC-PK1 cells

    T. Katsura;C. E. Gustafson;D. A. Ausiello;D. Brown

  • Commensal-associated molecular patterns induce selective toll-like receptor-trafficking from apical membrane to cytoplasmic compartments in polarized intestinal epithelium.

    Elke Cario;Dennis Brown;Mary McKee;Kathryn Lynch-Devaney

  • Antigen retrieval in cryostat tissue sections and cultured cells by treatment with sodium dodecyl sulfate (SDS)

    Dennis Brown;John Lydon;Margaret McLaughlin;Alan Stuart-Tilley

  • V‐ATPase Interacts with ARNO and Arf6 in Early Endosomes and Regulates the Protein Degradative Pathway

    Andres Hurtado-Lorenzo;Mhairi Skinner;Jaafar El Annan;Masamitsu Futai

Frequent Co-Authors

Sylvie Breton
Sylvie Breton Harvard University
Dennis A. Ausiello
Dennis A. Ausiello Harvard University
Alan S. Verkman
Alan S. Verkman University of California, San Francisco
Stephen L. Gluck
Stephen L. Gluck University of Florida
Seth L. Alper
Seth L. Alper Beth Israel Deaconess Medical Center
Carsten A. Wagner
Carsten A. Wagner University of Zurich
Joseph V. Bonventre
Joseph V. Bonventre Brigham and Women's Hospital
Xandra O. Breakefield
Xandra O. Breakefield Harvard University
Peter Smith
Peter Smith University of Aberdeen
Tonghui Ma
Tonghui Ma Dalian Medical University

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