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Biology and Biochemistry
Japan
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
95
Citations
29435
World Ranking
1926
National Ranking
109

Medicine

D-Index
95
Citations
29497
World Ranking
10153
National Ranking
284

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Sei Sasaki is affiliated with Tokyo Medical and Dental University in Japan and works primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research focuses on molecular biology aspects related to ion transport and channel regulation, with a significant emphasis on renal function and water balance.

The main topics covered in Sei Sasaki's research include:

  • Ion Transport and Channel Regulation
  • Electrolyte and hormonal disorders
  • Ion channel regulation and function
  • Renal function and acid-base balance
  • Erythrocyte Function and Pathophysiology
  • Renal Diseases and Glomerulopathies
  • Nephrotoxicity and Medicinal Plants

They have contributed to the broader understanding of water balance disorders and kidney function through publications in notable scientific journals.

Selected recent papers by Sei Sasaki include:

  • Updates and Perspectives on Aquaporin-2 and Water Balance Disorders, 2021, International Journal of Molecular Sciences
  • LRBA is essential for urinary concentration and body water homeostasis, 2022, Proceedings of the National Academy of Sciences
  • Minimal change disease concurrent with acute interstitial nephritis after long-term use of sorafenib in a patient with renal cell carcinoma, 2021, CEN Case Reports
  • Phosphorylation profile of human AQP2 in urinary exosomes by LC-MS/MS phosphoproteomic analysis, 2020, Clinical and Experimental Nephrology
  • The Phosphorylated States of Human Aquaporin 2 Revealed by Liquid Chromatography Coupled to Tandem Mass Spectrometry Phosphoproteomic Analysis of Urinary Exosomes, 2020, Journal of the American Society of Nephrology

Their frequent co-authors include:

  • Yumi Noda
  • Tatemitsu Rai
  • Shinichi Uchida
  • Yasuko Tanaka
  • Kenichi Ishibashi

Sei Sasaki's work has been published in recurring venues that specialize in nephrology and molecular biology, with frequent publications appearing in:

  • Journal of the American Society of Nephrology
  • International Journal of Molecular Sciences
  • Proceedings of the National Academy of Sciences
  • CEN Case Reports
  • Clinical and Experimental Nephrology

Best Publications

  • Cloning and expression of apical membrane water channel of rat kidney collecting tubule

    K Fushimi;S Uchida;Y Hara;Y Hirata

  • Phosphorylation of Serine 256 Is Required for cAMP-dependent Regulatory Exocytosis of the Aquaporin-2 Water Channel

    Kiyohide Fushimi;Sei Sasaki;Fumiaki Marumo

  • Molecular cloning and expression of a member of the aquaporin family with permeability to glycerol and urea in addition to water expressed at the basolateral membrane of kidney collecting duct cells

    K Ishibashi;S Sasaki;K Fushimi;S Uchida

  • Cloning and Functional Expression of a New Water Channel Abundantly Expressed in the Testis Permeable to Water, Glycerol, and Urea *

    Kenichi Ishibashi;Michio Kuwahara;Yong Gu;Yukio Kageyama

  • Aquaporins: a family of water channel proteins.

    P. Agre;S. Sasaki;M. J. Chrispeels

  • Implications of the aquaporin-4 structure on array formation and cell adhesion.

    Yoko Hiroaki;Kazutoshi Tani;Akiko Kamegawa;Nobuhiko Gyobu

  • Cloning and functional expression of a new aquaporin (AQP9) abundantly expressed in the peripheral leukocytes permeable to water and urea, but not to glycerol.

    Kenichi Ishibashi;Michio Kuwahara;Yong Gu;Yujiro Tanaka

  • Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins

    Kozue Yamauchi;Tatemitsu Rai;Katsuki Kobayashi;Eisei Sohara

  • Diagnostic usefulness of bone mineral density and biochemical markers of bone turnover in predicting fracture in CKD stage 5D patients—a single-center cohort study

    Soichiro Iimori;Yoshihiro Mori;Wataru Akita;Tamaki Kuyama

  • Molecular Pathogenesis of Pseudohypoaldosteronism Type II: Generation and Analysis of a Wnk4D561A/+ Knockin Mouse Model

    Sung-Sen Yang;Tetsuji Morimoto;Tatemitsu Rai;Motoko Chiga

  • Molecular cloning of a chloride channel that is regulated by dehydration and expressed predominantly in kidney medulla.

    S Uchida;S Sasaki;T Furukawa;M Hiraoka

  • Transcriptional regulation of aquaporin-2 water channel gene by cAMP.

    Y Matsumura;S Uchida;T Rai;S Sasaki

  • Cloning and expression of a protein kinase C-regulated chloride channel abundantly expressed in rat brain neuronal cells.

    Masanobu Kawasaki;Shinichi Uchida;Toshiaki Monkawa;Toshiaki Monkawa;Atsushi Miyawaki

  • Progressive adipocyte hypertrophy in aquaporin-7-deficient mice: adipocyte glycerol permeability as a novel regulator of fat accumulation.

    Mariko Hara-Chikuma;Eisei Sohara;Tatemitsu Rai;Masahito Ikawa

  • Urinary excretion of aquaporin-2 in patients with diabetes insipidus.

    Kazuo Kanno;Sei Sasaki;Yukio Hirata;San E. Ishikawa

  • Disruption of Aquaporin-11 Produces Polycystic Kidneys following Vacuolization of the Proximal Tubule

    Yoshiyuki Morishita;Toshiyuki Matsuzaki;Mariko Hara-chikuma;Ayaka Andoo

  • SPAK-Knockout Mice Manifest Gitelman Syndrome and Impaired Vasoconstriction

    Sung-Sen Yang;Yi-Fen Lo;Chin-Chen Wu;Shu-Wha Lin

  • cAMP-dependent Phosphorylation Stimulates Water Permeability of Aquaporin-collecting Duct Water Channel Protein Expressed in Xenopus Oocytes

    Michio Kuwahara;Kiyohide Fushimi;Yoshio Terada;Liqun Bai

  • Identification of a novel aquaporin, AQP12, expressed in pancreatic acinar cells

    Tomohiro Itoh;Tatemitsu Rai;Michio Kuwahara;Shigeru B.H. Ko

  • Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel

    Yoshihiro Matsumura;Shinichi Uchida;Yoshiaki Kondo;Hiroaki Miyazaki

Frequent Co-Authors

Shinichi Uchida
Shinichi Uchida Tokyo Medical and Dental University
Fumiaki Marumo
Fumiaki Marumo Tokyo Medical and Dental University
Kenichi Ishibashi
Kenichi Ishibashi Meiji Pharmaceutical University
Yoshinori Fujiyoshi
Yoshinori Fujiyoshi Nagoya University
Yukio Hirata
Yukio Hirata Tokyo Medical and Dental University
Alan S. Verkman
Alan S. Verkman University of California, San Francisco
Kuniaki Takata
Kuniaki Takata Gunma University
Daniel G. Bichet
Daniel G. Bichet University of Montreal
Dario R. Alessi
Dario R. Alessi University of Dundee
Claudio Ronco
Claudio Ronco University of Padua

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