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Medicine

D-Index
84
Citations
28581
World Ranking
15004
National Ranking
457

Overview

Yukio Hirata is affiliated with Tokyo Medical and Dental University in Japan. Their research spans multiple disciplines within biochemistry, genetics, molecular biology, and medicine, reflecting a broad engagement with topics related to cellular and molecular mechanisms underlying health and disease.

The primary fields of study in Hirata's work include Biochemistry, Genetics and Molecular Biology, with 59 publications, and Medicine, accounting for 46 publications. Within these domains, subfields frequently addressed are Molecular Biology (29 publications), Cell Biology (20), Neurology (10), Pulmonary and Respiratory Medicine (9), and Physiology (9).

Key research topics covered by Hirata's publications include:

  • Endoplasmic Reticulum Stress and Disease
  • Ferroptosis and cancer prognosis
  • RNA regulation and disease
  • RNA modifications and cancer
  • Muscle metabolism and nutrition
  • Autophagy in Disease and Therapy
  • Genomics, phytochemicals, and oxidative stress

Notable recent papers by Hirata include:

  • "Quercetin and resveratrol inhibit ferroptosis independently of Nrf2-ARE activation in mouse hippocampal HT22 cells," 2022, published in Food and Chemical Toxicology
  • "Distinctive effects of executive dysfunction and loss of learning/memory abilities on resting-state brain activity," 2022, published in Scientific Reports
  • "Oxindole-curcumin hybrid compound enhances the transcription of γ-glutamylcysteine ligase," 2021, published in European Journal of Pharmacology
  • "Identification of novel neuroprotective N,N-dimethylaniline derivatives that prevent oxytosis/ferroptosis and localize to late endosomes and lysosomes," 2021, published in Free Radical Biology and Medicine
  • "Elucidation of brefeldin A-induced ER and Golgi stress responses in Neuro2a cells," 2021, published in Molecular and Cellular Biochemistry

Frequent publication venues for Hirata's work include Molecular Biology Reports (4 publications), Scientific Reports (3), European Journal of Pharmacology (3), ACS Chemical Neuroscience (3), and Food and Chemical Toxicology (2).

Collaborations form a significant part of Hirata's research activities. Frequently co-authoring researchers are:

  • Kentaro Oh-hashi (23 joint publications)
  • Kyoji Furuta (15)
  • Hiroshi Takemori (10)
  • Yuji O. Kamatari (8)
  • Kyoka Kawaguchi (5)

Best Publications

  • Cloning and expression of apical membrane water channel of rat kidney collecting tubule

    K Fushimi;S Uchida;Y Hara;Y Hirata

  • Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes.

    H Ito;Y Hirata;S Adachi;M Tanaka

  • Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells.

    Y Hirata;T Emori;S Eguchi;K Kanno

  • Endothelin is a potent mitogen for rat vascular smooth muscle cells

    Yukio Hirata;Yasuyuki Takagi;Yuka Fukuda;Fumiaki Marumo

  • Endothelin-1 induces hypertrophy with enhanced expression of muscle-specific genes in cultured neonatal rat cardiomyocytes.

    H Ito;Y Hirata;M Hiroe;M Tsujino

  • Calcium-dependent Epidermal Growth Factor Receptor Transactivation Mediates the Angiotensin II-induced Mitogen-activated Protein Kinase Activation in Vascular Smooth Muscle Cells

    Satoru Eguchi;Satoru Eguchi;Kotaro Numaguchi;Hiroaki Iwasaki;Takeshi Matsumoto

  • Insulin-like growth factor-I induces hypertrophy with enhanced expression of muscle specific genes in cultured rat cardiomyocytes.

    H Ito;M Hiroe;Y Hirata;M Tsujino

  • Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides

    H Sakurai;H Kohsaka;M F Liu;H Higashiyama

  • Induction of endothelin-1 gene by angiotensin and vasopressin in endothelial cells.

    Taihei Imai;Yukio Hirata;Toshiaki Emori;Masashi Yanagisawa

  • Epidemiological study of gastroenteropancreatic neuroendocrine tumors in Japan

    Tetsuhide Ito;Hironobu Sasano;Masao Tanaka;R. Yoshiyuki Osamura

  • Plasma Endothelin Levels in Hypertension and Chronic Renal Failure

    Masayoshi Shichiri;Yukio Hirata;Kenji Ando;Toshiaki Emori

  • Secretory mechanism of immunoreactive endothelin in cultured bovine endothelial cells.

    Toshiaki Emori;Yukio Hirata;Kazuki Ohta;Masayoshi Shichiri

  • Autoradiographic distribution in rat tissues of binding sites for endothelin: a neuropeptide?

    Chizuko Koseki;Masashi Imai;Yukio Hirata;Masashi Yanagisawa

  • Increased circulating adrenomedullin, a novel vasodilatory peptide, in sepsis.

    Y Hirata;C Mitaka;K Sato;T Nagura

  • Endothelin is a potent secretagogue for atrial natriuretic peptide in cultured rat atrial myocytes

    Yuka Fukuda;Yukio Hirata;Hiroki Yoshimi;Takatsugu Kojima

  • Specific receptors for adrenomedullin in cultured rat vascular smooth muscle cells

    Satoru Eguchi;Yukio Hirata;Hiroaki Kano;Kyoko Sato

  • RAISED PLASMA ENDOTHELIN IN ANEURYSMAL SUBARACHNOID HAEMORRHAGE

    Hiroyuki Masaoka;Ryuta Suzuki;Yukio Hirata;Toshiaki Emori

  • Natriuretic peptides inhibit angiotensin II-induced proliferation of rat cardiac fibroblasts by blocking endothelin-1 gene expression.

    H. Fujisaki;H. Ito;Y. Hirata;M. Tanaka

  • Presence of immunoreactive endothelin in human plasma.

    K. Ando;Y. Hirata;M. Shichiri;T. Emori

  • Molecular cloning of a chloride channel that is regulated by dehydration and expressed predominantly in kidney medulla.

    S Uchida;S Sasaki;T Furukawa;M Hiraoka

Frequent Co-Authors

Fumiaki Marumo
Fumiaki Marumo Tokyo Medical and Dental University
Masashi Yanagisawa
Masashi Yanagisawa University of Tsukuba
Tomoh Masaki
Tomoh Masaki Kyoto University
Sei Sasaki
Sei Sasaki Tokyo Medical and Dental University
Hironobu Sasano
Hironobu Sasano Tohoku University
Yoshihiro Ogawa
Yoshihiro Ogawa Kyushu University
Tadashi Inagami
Tadashi Inagami Vanderbilt University
Shigehisa Hirose
Shigehisa Hirose Tokyo Institute of Technology
Shumpei Sakakibara
Shumpei Sakakibara Osaka University
Masato Tanaka
Masato Tanaka Tokyo University of Pharmacy and Life Sciences

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