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D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Biology and Biochemistry 71 6804 6273 457 427 313 13992

Shigehisa Hirose publications per year

The chart shows the history of publications by Shigehisa Hirose between 1971 and 2024, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Shigehisa Hirose published across 54 years, from 1971 to 2024, averaging 5.9 papers a year. Output peaked at 14 publications in 1996. 2 of the 316 publications appeared in the last two years.

No. of publications
5 10
Bar chart. Horizontal axis: year, 1971 to 2024. Vertical axis: number of publications, 0 to 14. Peak 14 publications in 1996. 1971: 2 publications 1972: 1 publication 1973: 3 publications 1974: 1 publication 1975: 5 publications 1976: 2 publications 1977: 3 publications 1978: 3 publications 1979: 1 publication 1980: 8 publications 1981: 6 publications 1982: 10 publications 1983: 5 publications 1984: 6 publications 1985: 4 publications 1986: 8 publications 1987: 5 publications 1988: 5 publications 1989: 11 publications 1990: 4 publications 1991: 10 publications 1992: 13 publications 1993: 7 publications 1994: 11 publications 1995: 11 publications 1996: 14 publications 1997: 12 publications 1998: 12 publications 1999: 12 publications 2000: 8 publications 2001: 8 publications 2002: 7 publications 2003: 5 publications 2004: 7 publications 2005: 8 publications 2006: 10 publications 2007: 11 publications 2008: 5 publications 2009: 4 publications 2010: 12 publications 2011: 6 publications 2012: 9 publications 2013: 8 publications 2014: 4 publications 2015: 2 publications 2016: 3 publications 2017: 0 publications 2018: 0 publications 2019: 1 publication 2020: 0 publications 2021: 0 publications 2022: 1 publication 2023: 1 publication 2024: 1 publication
1971 2024

316 publications in total across all disciplines

View publications per year as a table
Shigehisa Hirose: publications per year, 1971 to 2024
Year Publications
1971 2
1972 1
1973 3
1974 1
1975 5
1976 2
1977 3
1978 3
1979 1
1980 8
1981 6
1982 10
1983 5
1984 6
1985 4
1986 8
1987 5
1988 5
1989 11
1990 4
1991 10
1992 13
1993 7
1994 11
1995 11
1996 14
1997 12
1998 12
1999 12
2000 8
2001 8
2002 7
2003 5
2004 7
2005 8
2006 10
2007 11
2008 5
2009 4
2010 12
2011 6
2012 9
2013 8
2014 4
2015 2
2016 3
2017 0
2018 0
2019 1
2020 0
2021 0
2022 1
2023 1
2024 1
Total 316
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Shigehisa Hirose publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Shigehisa Hirose sits on this spectrum.

No. of scientists
200 400 600 800
Bar chart with 100 bars. Horizontal axis: publications, 47–56 to 1,028+. Vertical axis: number of scientists, 0 to 980. Most scientists, 980, have 127–136 publications. The last bar groups every scientist with 1,028 publications or more. The highlighted bar, 307–316 publications, is where this scientist sits. 47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientist 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientist 1,028+ publications: 100 scientists
47–56 publications 1,028+

This scientist: 313 publications — 80th percentile

80% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

View publications distribution as a table
Number of Biology and Biochemistry scientists by publication count, Research.com 2026 ranking edition. Based on 19,587 ranked scientists.
Publications Scientists This scientist
47–56 8
57–66 35
67–76 106
77–86 231
87–96 413
97–106 546
107–116 704
117–126 848
127–136 980
137–146 942
147–156 969
157–166 949
167–176 951
177–186 915
187–196 787
197–206 840
207–216 733
217–226 708
227–236 651
237–246 605
247–256 510
257–266 524
267–276 434
277–286 417
287–296 350
297–306 363
307–316 315 313
317–326 296
327–336 261
337–346 240
347–356 219
357–366 196
367–376 154
377–386 161
387–396 155
397–406 145
407–416 124
417–426 112
427–436 132
437–446 116
447–456 99
457–466 81
467–476 91
477–486 80
487–496 80
497–506 59
507–516 36
517–526 46
527–536 54
537–546 44
547–556 43
557–566 43
567–576 42
577–586 25
587–596 34
597–606 23
607–616 33
617–626 31
627–636 27
637–646 25
647–656 28
657–666 34
667–676 18
677–686 16
687–696 10
697–706 12
707–716 21
717–726 12
727–736 12
737–746 10
747–756 7
757–766 13
767–776 15
777–786 13
787–796 9
797–806 9
807–816 7
817–826 4
827–836 9
837–846 7
847–856 3
857–866 5
867–876 5
877–886 11
887–896 3
897–906 4
907–916 7
917–926 5
927–936 6
937–946 6
947–956 3
957–966 7
967–976 2
977–986 2
987–996 1
997–1,006 5
1,007–1,016 2
1,017–1,026 2
1,027 1
1,028+ 100
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Shigehisa Hirose D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Shigehisa Hirose sits on this spectrum.

No. of scientists
250 500 750 1,000 1,250
Bar chart with 65 bars. Horizontal axis: D-Index, 40–41 to 167+. Vertical axis: number of scientists, 0 to 1,253. Most scientists, 1,253, have 58–59 D-Index. The last bar groups every scientist with 167 D-Index or more. The highlighted bar, 70–71 D-Index, is where this scientist sits. 40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40–41 D-Index 167+

This scientist: 71 D-Index — 67th percentile

67% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

View D-Index distribution as a table
Number of Biology and Biochemistry scientists by D-index, Research.com 2026 ranking edition. Based on 19,587 ranked scientists.
D-Index Scientists This scientist
40–41 80
42–43 183
44–45 316
46–47 504
48–49 718
50–51 899
52–53 1,025
54–55 1,149
56–57 1,235
58–59 1,253
60–61 1,162
62–63 1,130
64–65 1,031
66–67 897
68–69 814
70–71 714 71
72–73 709
74–75 596
76–77 512
78–79 473
80–81 412
82–83 373
84–85 358
86–87 285
88–89 273
90–91 227
92–93 208
94–95 193
96–97 153
98–99 157
100–101 148
102–103 120
104–105 113
106–107 100
108–109 86
110–111 67
112–113 71
114–115 73
116–117 64
118–119 53
120–121 60
122–123 54
124–125 43
126–127 38
128–129 49
130–131 26
132–133 18
134–135 23
136–137 32
138–139 32
140–141 27
142–143 19
144–145 22
146–147 12
148–149 16
150–151 14
152–153 10
154–155 13
156–157 10
158–159 7
160–161 9
162–163 13
164–165 4
166 4
167+ 98
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Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Amino acid

Shigehisa Hirose mostly deals with Biochemistry, Molecular biology, Endocrinology, Internal medicine and Peptide sequence. Shigehisa Hirose frequently studies issues relating to Cell biology and Biochemistry. The various areas that he examines in his Molecular biology study include Amino acid and Complementary DNA, Gene expression, Gene, Recombinant DNA.

Shigehisa Hirose combines subjects such as Receptor, Basement membrane, Alkaline phosphatase and Osteoblast with his study of Endocrinology. His Receptor study incorporates themes from Messenger RNA and Atrial natriuretic peptide. The Peptide sequence study combines topics in areas such as Elafin and G protein-coupled receptor.

His most cited work include:

  • Cloning and sequence analysis of cDNA for human renin precursor (221 citations)
  • The trappin gene family: proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide core (169 citations)
  • Enhanced Expression of Endothelial Oxidized Low-Density Lipoprotein Receptor (LOX-1) in Hypertensive Rats (142 citations)

What are the main themes of his work throughout his whole career to date?

Biochemistry, Endocrinology, Internal medicine, Molecular biology and Receptor are his primary areas of study. His work deals with themes such as Gene expression, Osteoblast and Cell biology, which intersect with Endocrinology. His Internal medicine study combines topics in areas such as Osteocalcin and Northern blot.

His Molecular biology research includes themes of Amino acid and Complementary DNA, cDNA library, Peptide sequence, Messenger RNA. His study in cDNA library is interdisciplinary in nature, drawing from both Open reading frame, Molecular cloning and Nucleic acid sequence. In the field of Receptor, his study on Endothelin receptor and Affinity labeling overlaps with subjects such as NPR2 and NPR1.

He most often published in these fields:

  • Biochemistry (37.91%)
  • Endocrinology (34.60%)
  • Internal medicine (34.60%)

What were the highlights of his more recent work (between 2009-2021)?

  • Molecular biology (33.65%)
  • Cell biology (16.59%)
  • Biochemistry (37.91%)

In recent papers he was focusing on the following fields of study:

Shigehisa Hirose mainly investigates Molecular biology, Cell biology, Biochemistry, Secretion and Apical membrane. His Molecular biology research is multidisciplinary, incorporating elements of Inflammation, Bronchoalveolar lavage, Lung, Kidney and Ubiquitin ligase. His Lung research focuses on Monocyte and how it connects with Receptor.

His biological study spans a wide range of topics, including Internal medicine and Endocrinology. His Endocrinology research incorporates themes from Calcitonin gene-related peptide and Ligand. Biochemistry is frequently linked to Sodium–hydrogen antiporter in his study.

Between 2009 and 2021, his most popular works were:

  • Free fatty acids induce transglutaminase 2-dependent apoptosis in hepatocytes via ER stress-stimulated PERK pathways. (53 citations)
  • Close Association of Carbonic Anhydrase (CA2a and CA15a), Na+/H+ Exchanger (Nhe3b), and Ammonia Transporter Rhcg1 in Zebrafish Ionocytes Responsible for Na+ Uptake (43 citations)
  • Lung Surfactant Levels are Regulated by Ig-Hepta/GPR116 by Monitoring Surfactant Protein D (43 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Amino acid

His primary scientific interests are in Molecular biology, Cell biology, Biochemistry, Extracellular and Ubiquitin ligase. His work in the fields of Molecular biology, such as Glycoprotein, overlaps with other areas such as Pulmonary Surfactant-Associated Protein D. The Cell biology study combines topics in areas such as Endocrinology, Toxicology, Gene expression and Mutant.

His work on Apical membrane as part of general Biochemistry study is frequently connected to Germination, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His Extracellular research includes elements of Surfactant homeostasis, Pulmonary alveolar proteinosis, Immunoprecipitation, Secretion and Pulmonary surfactant. In Ubiquitin ligase, Shigehisa Hirose works on issues like Transmembrane protein, which are connected to Protease, Endoplasmic-reticulum-associated protein degradation, Deubiquitination, Ubiquitin and Deubiquitinating enzyme.

Best Publications

  • MARCH‐V is a novel mitofusin 2‐ and Drp1‐binding protein able to change mitochondrial morphology

    Nobuhiro Nakamura;Yasuo Kimura;Masaki Tokuda;Shinji Honda

  • Cloning and sequence analysis of cDNA for human renin precursor

    Takashi Imai;Hitoshi Miyazaki;Shigehisa Hirose;Hitoshi Hori

  • Molecular biology of major components of chloride cells.

    Shigehisa Hirose;Toyoji Kaneko;Nobuko Naito;Yoshio Takei

  • Mechanism of acid adaptation of a fish living in a pH 3.5 lake

    Taku Hirata;Toyoji Kaneko;Toshihiro Ono;Takeru Nakazato

  • The trappin gene family: proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide core

    Joost Schalkwijk;Oliver Wiedow;Shigehisa Hirose

  • Regulation of Mitochondrial Morphology by USP30, a Deubiquitinating Enzyme Present in the Mitochondrial Outer Membrane

    Nobuhiro Nakamura;Shigehisa Hirose

  • Enhanced Expression of Endothelial Oxidized Low-Density Lipoprotein Receptor (LOX-1) in Hypertensive Rats

    Miki Nagase;Shigehisa Hirose;Tatsuya Sawamura;Tomoh Masaki

  • Characterization of osteoblastic differentiation of stromal cell line ST2 that is induced by ascorbic acid

    Eri Otsuka;Akira Yamaguchi;Shigehisa Hirose;Hiromi Hagiwara

  • Visualization in zebrafish larvae of Na+ uptake in mitochondria-rich cells whose differentiation is dependent on foxi3a

    Masahiro Esaki;Kazuyuki Hoshijima;Sayako Kobayashi;Hidekazu Fukuda

  • cGMP produced in response to ANP and CNP regulates proliferation and differentiation of osteoblastic cells

    H. Hagiwara;A. Inoue;A. Yamaguchi;S. Yokose

  • Localization of ammonia transporter Rhcg1 in mitochondrion-rich cells of yolk sac, gill, and kidney of zebrafish and its ionic strength-dependent expression

    Tsutomu Nakada;Kazuyuki Hoshijima;Masahiro Esaki;Saori Nagayoshi

  • Inwardly rectifying K+ channel Kir7.1 is highly expressed in thyroid follicular cells, intestinal epithelial cells and choroid plexus epithelial cells: implication for a functional coupling with Na+,K+-ATPase.

    Nobuhiro Nakamura;Yoshiro Suzuki;Hidenari Sakuta;Kayoko Ookata

  • Autocrine regulation of rat chondrocyte proliferation by natriuretic peptide C and its receptor, natriuretic peptide receptor-B.

    H Hagiwara;H Sakaguchi;M Itakura;T Yoshimoto

  • Dimerization of Midkine by Tissue Transglutaminase and Its Functional Implication

    Soichi Kojima;Tatsuya Inui;Hisako Muramatsu;Yohko Suzuki

  • Elastase inhibitor elafin is a new type of proteinase inhibitor which has a transglutaminase-mediated anchoring sequence termed "cementoin".

    Kiyomitsu Nara;Shiho Ito;Teizo Ito;Yohko Suzuki

  • Genomic organization and regulation of expression of the lectin-like oxidized low-density lipoprotein receptor (LOX-1) gene.

    Miki Nagase;Junpei Abe;Katsutoshi Takahashi;Joji Ando

  • Structure of the human renin gene.

    Hitoshi Miyazaki;Akiyoshi Fukamizu;Shigehisa Hirose;Takashi Hayashi

  • Cloning and sequence analysis of a cDNA encoding human non-selective type of endothelin receptor.

    Makoto Nakamuta;Ryoichi Takayanagi;Yoshiyuki Sakai;Shigeru Sakamoto

  • Effects of nicotine on cultured cells suggest that it can influence the formation and resorption of bone

    Sachiko Yuhara;Satoshi Kasagi;Atsuto Inoue;Eri Otsuka

  • Multiplicity, structures, and endocrine and exocrine natures of eel fucose-binding lectins.

    Shinji Honda;Masahide Kashiwagi;Kentaro Miyamoto;Yoshio Takei

Frequent Co-Authors

Kazuo Murakami
Kazuo Murakami University of Tsukuba
Yuji Inada
Yuji Inada Toin University of Yokohama
Hiroshi Demura
Hiroshi Demura Tohoku University
Yoshio Takei
Yoshio Takei University of Tokyo
Akira Yamaguchi
Akira Yamaguchi Tokyo Dental College
Tadashi Inagami
Tadashi Inagami Vanderbilt University
Soichi Kojima
Soichi Kojima RIKEN Center for Integrative Medical Sciences
Naoto Ueno
Naoto Ueno National Institute for Basic Biology
Martin Griffin
Martin Griffin Aston University

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