World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
112
Citations
43031
World Ranking
5171
National Ranking
2798

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Ernesto Canalis is affiliated with the University of Connecticut Health Center in the United States. Their research primarily focuses on molecular biology and biochemistry within the broader context of medical science, with a significant concentration on bone metabolism and related disorders. The scientist has contributed to understanding the molecular regulation of bone biology, particularly through signaling pathways and developmental biology mechanisms.

The main fields of study where Ernesto Canalis has a considerable presence include Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their work also spans several subfields, including Molecular Biology, Genetics, Endocrinology, Diabetes and Metabolism, Immunology, and Oncology. The scientist's research topics prominently feature Developmental Biology and Gene Regulation, Bone Metabolism and Diseases, TGF-β signaling in diseases, Craniofacial Disorders and Treatments, Growth Hormone and Insulin-like Growth Factors, Bone health and treatments, and Osteoarthritis Treatment and Mechanisms.

Ernesto Canalis has authored multiple papers in well-regarded journals. Some of the recent publications include:

  • Skeletal disorders associated with the growth hormone-insulin-like growth factor 1 axis, 2022, Nature Reviews Endocrinology
  • Notch and the regulation of osteoclast differentiation and function, 2020, Bone
  • ENDOCRINOLOGY IN THE TIME OF COVID-19: Management of calcium metabolic disorders and osteoporosis, 2020, European Journal of Endocrinology
  • Antisense oligonucleotides targeting Notch2 ameliorate the osteopenic phenotype in a mouse model of Hajdu-Cheney syndrome, 2020, Journal of Biological Chemistry
  • New insights into the vitamin D/PTH axis in endocrine-driven metabolic bone diseases, 2024, Endocrine

The scientist has frequently published in venues such as Bone and the Journal of Biological Chemistry, each with six publications, as well as PLoS ONE and the Journal of Endocrinological Investigation. They also have publications in Nature Reviews Endocrinology. These journals align with their focus on bone biology, endocrinology, and molecular mechanisms related to skeletal health.

Ernesto Canalis often collaborates with other researchers, with frequent co-authors including Lauren Schilling, Jungeun Yu, Tabitha Eller, Emily Denker, and Michele Carrer. These partnerships reflect a collaborative engagement within their field of study, particularly in research related to bone metabolism and molecular signaling.

Among professional recognitions, Ernesto Canalis is noted as a member of the Association of American Physicians, indicating a professional standing within the medical research community.

Best Publications

  • Glucocorticoid-induced osteoporosis: pathophysiology and therapy.

    E. Canalis;G. Mazziotti;A. Giustina;J. P. Bilezikian

  • Bone morphogenetic proteins, their antagonists, and the skeleton.

    Ernesto Canalis;Ernesto Canalis;Aris N. Economides;Elisabetta Gazzerro;Elisabetta Gazzerro

  • Growth Hormone, Insulin-Like Growth Factors, and the Skeleton

    Andrea Giustina;Gherardo Mazziotti;Ernesto Canalis

  • Transforming growth factor beta is a bifunctional regulator of replication and collagen synthesis in osteoblast-enriched cell cultures from fetal rat bone.

    M Centrella;T L McCarthy;E Canalis

  • Insulin-like growth factor I has independent effects on bone matrix formation and cell replication.

    Janet M. Hock;Michael Centrella;Ernesto Canalis

  • Growth factors and the regulation of bone remodeling.

    E Canalis;T McCarthy;M Centrella

  • Mechanisms of Anabolic Therapies for Osteoporosis

    Ernesto Canalis;Andrea Giustina;John P. Bilezikian

  • Insulin-like growth factor I mediates selective anabolic effects of parathyroid hormone in bone cultures.

    E Canalis;M Centrella;W Burch;T L McCarthy

  • The divalent strontium salt S12911 enhances bone cell replication and bone formation in vitro.

    E. Canalis;M. Hott;P. Deloffre;Y. Tsouderos

  • Clinical review 83: Mechanisms of glucocorticoid action in bone: implications to glucocorticoid-induced osteoporosis.

    E Canalis

  • Age‐Related Changes in Trabecular Architecture Differ in Female and Male C57BL/6J Mice

    Vaida Glatt;Ernesto Canalis;Lisa Stadmeyer;Mary L Bouxsein

  • Regulatory Effects of Insulin-Like Growth Factors I and II on Bone Collagen Synthesis in Rat Calvarial Cultures

    Thomas L. Mccarthy;Michael Centrella;Ernesto Canalis

  • Effect of insulinlike growth factor I on DNA and protein synthesis in cultured rat calvaria.

    Ernesto Canalis

  • Mechanisms of glucocorticoid action in bone.

    Ernesto Canalis;Ernesto Canalis;Anne M. Delany;Anne M. Delany

  • Effects of basic fibroblast growth factor on bone formation in vitro.

    E Canalis;M Centrella;T McCarthy

  • Direct stimulation of bone resorption by thyroid hormones.

    G R Mundy;J L Shapiro;J G Bandelin;E M Canalis

  • Parathyroid hormone enhances the transcript and polypeptide levels of insulin-like growth factor I in osteoblast-enriched cultures from fetal rat bone.

    Thomas L. Mccarthy;Michael Centrella;Ernesto Canalis

  • Bone morphogenetic proteins and their antagonists

    Elisabetta Gazzerro;Ernesto Canalis;Ernesto Canalis

  • Glucocorticoid-induced osteoporosis: an update.

    Gherardo Mazziotti;Alberto Angeli;John P. Bilezikian;Ernesto Canalis

  • BONE MORPHOGENETIC PROTEINS INDUCE THE EXPRESSION OF NOGGIN, WHICH LIMITS THEIR ACTIVITY IN CULTURED RAT OSTEOBLASTS

    Elisabetta Gazzerro;Valerie Gangji;Ernesto Canalis

Frequent Co-Authors

Michael Centrella
Michael Centrella Yale University
Thomas L. McCarthy
Thomas L. McCarthy Yale University
Aris N. Economides
Aris N. Economides Regeneron (United States)
Clifford J. Rosen
Clifford J. Rosen Maine Medical Center
Andrea Giustina
Andrea Giustina Vita-Salute San Raffaele University
Lawrence G. Raisz
Lawrence G. Raisz University of Connecticut Health Center
Mary L. Bouxsein
Mary L. Bouxsein Beth Israel Deaconess Medical Center
Gregory R. Mundy
Gregory R. Mundy Vanderbilt University
David R. Clemmons
David R. Clemmons University of North Carolina at Chapel Hill
John P. Bilezikian
John P. Bilezikian Columbia University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you're considering a career in medicine but want flexible options or alternative routes, several related online degrees can help you achieve your goals. Many prospective healthcare professionals look for lpn program no entrance exam pathways, which allow entry into nursing fields without standardized admissions tests, making nursing more accessible for diverse applicants.

For those interested in healthcare management, earning a health care administration degree online opens up careers in hospital administration, clinic management, and policy advising—roles that are crucial in today’s complex medical landscape.

Nurses aiming to advance their qualifications can explore adn to fnp bridge programs. These programs provide a streamlined path from an Associate Degree in Nursing to a Family Nurse Practitioner credential, significantly expanding professional opportunities and scope of practice.

Additionally, students interested in nutrition-related health fields can pursue an online degree nutrition, preparing for roles such as dietitian, health coach, or public health advocate. Online learning options offer the flexibility needed for balancing studies with other commitments, making healthcare careers more attainable for a wide range of students.

Best Scientists Citing Ernesto Canalis

Trending Scientists

Recently Published Articles