D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 108 Citations 39,084 336 World Ranking 3545 National Ranking 2006

Research.com Recognitions

Awards & Achievements

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Endocrinology

His primary areas of investigation include Internal medicine, Endocrinology, Osteoblast, Growth factor and Bone cell. Bone resorption, Bone remodeling, Osteoporosis, Parathyroid hormone and Glucocorticoid are the core of his Internal medicine study. The concepts of his Endocrinology study are interwoven with issues in Calvaria, DNA synthesis, Cell biology and Osteocalcin, Alkaline phosphatase.

While the research belongs to areas of Osteoblast, he spends his time largely on the problem of Cellular differentiation, intersecting his research to questions surrounding Notch signaling pathway and Wnt signaling pathway. His work deals with themes such as Transforming growth factor and Cell culture, which intersect with Growth factor. His work investigates the relationship between Bone cell and topics such as Cell growth that intersect with problems in Osteocyte.

His most cited work include:

  • Bone morphogenetic proteins, their antagonists, and the skeleton. (772 citations)
  • Bone morphogenetic proteins, their antagonists, and the skeleton. (772 citations)
  • Glucocorticoid-induced osteoporosis: pathophysiology and therapy. (716 citations)

What are the main themes of his work throughout his whole career to date?

Ernesto Canalis mainly focuses on Internal medicine, Endocrinology, Osteoblast, Growth factor and Molecular biology. His Internal medicine research includes themes of Bone morphogenetic protein and DNA synthesis. His Endocrinology study combines topics from a wide range of disciplines, such as Osteocalcin and Cell biology.

His Osteoblast study incorporates themes from Stromal cell, Cycloheximide, Cellular differentiation, Osteoclast and Messenger RNA. His Growth factor research is multidisciplinary, relying on both Cell culture and Northern blot. His studies in Molecular biology integrate themes in fields like Autocrine signalling, RNA, Transcription factor, Collagenase and Binding site.

He most often published in these fields:

  • Internal medicine (93.82%)
  • Endocrinology (93.36%)
  • Osteoblast (52.63%)

What were the highlights of his more recent work (between 2012-2021)?

  • Internal medicine (93.82%)
  • Endocrinology (93.36%)
  • Bone resorption (28.60%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Internal medicine, Endocrinology, Bone resorption, Notch signaling pathway and Osteoblast. His study in the field of Bone density is also linked to topics like Endocrine disease. His research integrates issues of Sclerostin and Parathyroid hormone in his study of Endocrinology.

His research in Bone resorption intersects with topics in Osteoprotegerin, Cellular differentiation, Cortical bone, Osteoclast and Osteocalcin. His study in Notch signaling pathway is interdisciplinary in nature, drawing from both Molecular biology, Wnt signaling pathway and Gene expression. His work focuses on many connections between Bone remodeling and other disciplines, such as HEY1, that overlap with his field of interest in Transgene.

Between 2012 and 2021, his most popular works were:

  • Wnt signalling in osteoporosis: mechanisms and novel therapeutic approaches (173 citations)
  • MANAGEMENT OF ENDOCRINE DISEASE: Secondary osteoporosis: pathophysiology and management (104 citations)
  • Notch Signaling and the Skeleton. (101 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Enzyme

Ernesto Canalis mainly investigates Internal medicine, Endocrinology, Bone resorption, Notch signaling pathway and Bone remodeling. His Internal medicine research incorporates themes from Wnt signaling pathway and Cellular differentiation. His Bone resorption research integrates issues from Cortical bone and Sclerostin.

His Cortical bone course of study focuses on Osteoclast and Osteoblast. His work in Notch signaling pathway covers topics such as Cell signaling which are related to areas like NFAT, HEY2, Hairless, Osteocyte and Transcription factor. Ernesto Canalis combines subjects such as Epithelial–mesenchymal transition, Autocrine signalling and Cytokine with his study of Cell biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Glucocorticoid-induced osteoporosis: pathophysiology and therapy.

E. Canalis;G. Mazziotti;A. Giustina;J. P. Bilezikian.
Osteoporosis International (2007)

1206 Citations

Bone morphogenetic proteins, their antagonists, and the skeleton.

Ernesto Canalis;Ernesto Canalis;Aris N. Economides;Elisabetta Gazzerro;Elisabetta Gazzerro.
Endocrine Reviews (2003)

1129 Citations

Transforming growth factor beta is a bifunctional regulator of replication and collagen synthesis in osteoblast-enriched cell cultures from fetal rat bone.

M Centrella;T L McCarthy;E Canalis.
Journal of Biological Chemistry (1987)

915 Citations

Growth Hormone, Insulin-Like Growth Factors, and the Skeleton

Andrea Giustina;Gherardo Mazziotti;Ernesto Canalis.
Endocrine Reviews (2008)

909 Citations

Insulin-like growth factor I has independent effects on bone matrix formation and cell replication.

Janet M. Hock;Michael Centrella;Ernesto Canalis.
Endocrinology (1988)

884 Citations

Growth factors and the regulation of bone remodeling.

E Canalis;T McCarthy;M Centrella.
Journal of Clinical Investigation (1988)

852 Citations

Insulin-like growth factor I mediates selective anabolic effects of parathyroid hormone in bone cultures.

E Canalis;M Centrella;W Burch;T L McCarthy.
Journal of Clinical Investigation (1989)

758 Citations

Mechanisms of Anabolic Therapies for Osteoporosis

Ernesto Canalis;Andrea Giustina;John P. Bilezikian.
The New England Journal of Medicine (2007)

741 Citations

The divalent strontium salt S12911 enhances bone cell replication and bone formation in vitro.

E. Canalis;M. Hott;P. Deloffre;Y. Tsouderos.
Bone (1996)

693 Citations

Clinical review 83: Mechanisms of glucocorticoid action in bone: implications to glucocorticoid-induced osteoporosis.

E Canalis.
The Journal of Clinical Endocrinology and Metabolism (1996)

670 Citations

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