D-Index & Metrics Best Publications
Research.com 2022 Best Female Scientist Award Badge
Molecular Biology
USA
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Best female scientists D-index 123 Citations 58,306 573 World Ranking 305 National Ranking 194
Medicine D-index 119 Citations 53,806 537 World Ranking 2187 National Ranking 1267
Molecular Biology D-index 125 Citations 58,683 556 World Ranking 129 National Ranking 86

Research.com Recognitions

Awards & Achievements

2023 - Research.com Molecular Biology in United States Leader Award

2022 - Research.com Best Female Scientist Award

2016 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • DNA
  • Transcription factor

Jane B. Lian mainly investigates Osteoblast, Molecular biology, Cell biology, Transcription factor and Cellular differentiation. Jane B. Lian has included themes like Endocrinology, Bone cell, Internal medicine, Osteocalcin and Extracellular matrix in her Osteoblast study. Her studies deal with areas such as Gene expression, Nuclear matrix, Chromatin, Regulation of gene expression and Transcription as well as Molecular biology.

Her Cell biology research includes elements of Cell cycle, microRNA and Immunology. Her Transcription factor research focuses on Promoter and how it relates to Repressor and Calcitriol receptor. Her research investigates the connection between Cellular differentiation and topics such as Osteocyte that intersect with issues in Secreted frizzled-related protein 1.

Her most cited work include:

  • Progressive development of the rat osteoblast phenotype in vitro: Reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix (1427 citations)
  • Osteocalcin and matrix Gla protein: vitamin K-dependent proteins in bone (1041 citations)
  • Molecular mechanisms mediating proliferation/differentiation interrelationships during progressive development of the osteoblast phenotype (930 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of study are Cell biology, Molecular biology, Transcription factor, Gene expression and Osteoblast. Her research in Cell biology intersects with topics in Nuclear matrix, Cell cycle, Cellular differentiation and Cell growth. Her work investigates the relationship between Molecular biology and topics such as Histone H2A that intersect with problems in Histone H4.

Her work deals with themes such as Chromatin, Promoter and Regulation of gene expression, which intersect with Transcription factor. Her work in Osteoblast covers topics such as Osteocalcin which are related to areas like Endocrinology, Internal medicine and Calcitriol receptor. Her RUNX2 research incorporates elements of Cancer research and Mesenchymal stem cell.

She most often published in these fields:

  • Cell biology (34.97%)
  • Molecular biology (32.43%)
  • Transcription factor (32.09%)

What were the highlights of her more recent work (between 2014-2021)?

  • Cancer research (21.62%)
  • Cell biology (34.97%)
  • Transcription factor (32.09%)

In recent papers she was focusing on the following fields of study:

Her primary areas of investigation include Cancer research, Cell biology, Transcription factor, Breast cancer and Cancer. Her Cancer research research integrates issues from Cancer cell, Carcinogenesis, Oncogene, microRNA and Tumor progression. The study incorporates disciplines such as Chromatin and RUNX2, Osteoblast in addition to Cell biology.

Her studies in Osteoblast integrate themes in fields like Osteoclast, Alkaline phosphatase and Cissus quadrangularis. Her Transcription factor research is multidisciplinary, incorporating perspectives in Cell cycle, Gene expression and Molecular biology. As a part of the same scientific family, Jane B. Lian mostly works in the field of Cancer, focusing on Cell growth and, on occasion, Cell culture.

Between 2014 and 2021, her most popular works were:

  • Chromatin interaction analysis reveals changes in small chromosome and telomere clustering between epithelial and breast cancer cells (132 citations)
  • Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease (125 citations)
  • Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease (125 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Cancer

Jane B. Lian mostly deals with Cancer research, Cancer, Breast cancer, Genetics and Chromatin. Her Cancer research study combines topics from a wide range of disciplines, such as Cell growth, Downregulation and upregulation, Transcription factor, Internal medicine and Triple-negative breast cancer. Her work carried out in the field of Transcription factor brings together such families of science as Chromatin immunoprecipitation and microRNA.

In her work, RUNX2 is strongly intertwined with Molecular biology, which is a subfield of Cancer. Her study explores the link between Genetics and topics such as Computational biology that cross with problems in Gene expression, Bone cell and Non-coding RNA. Her Chromatin research is multidisciplinary, relying on both Chromosome conformation capture, Suppressor and Cell biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The ENCODE (ENCyclopedia of DNA elements) Project

E. A. Feingold;P. J. Good;M. S. Guyer;S. Kamholz.
Science (2004)

2921 Citations

Progressive development of the rat osteoblast phenotype in vitro: Reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix

Thomas A. Owen;Michael A. Aronow;Victoria Shalhoub;Leesa M. Barone.
Journal of Cellular Physiology (1990)

2317 Citations

Osteocalcin and matrix Gla protein: vitamin K-dependent proteins in bone

P. V. Hauschka;J. B. Lian;D. E. C. Cole;C. M. Gundberg.
Physiological Reviews (1989)

1665 Citations

Molecular mechanisms mediating proliferation/differentiation interrelationships during progressive development of the osteoblast phenotype

Gary S. Stein;Jane B. Lian.
Endocrine Reviews (1993)

1524 Citations

Relationship of cell growth to the regulation of tissue-specific gene expression during osteoblast differentiation.

Gary S. Stein;Jane B. Lian;Thomas A. Owen.
The FASEB Journal (1990)

1329 Citations

Canonical WNT Signaling Promotes Osteogenesis by Directly Stimulating Runx2 Gene Expression

Tripti Gaur;Christopher J. Lengner;Hayk Hovhannisyan;Ramesh A. Bhat.
Journal of Biological Chemistry (2005)

1284 Citations

Concepts of Osteoblast Growth and Differentiation: Basis for Modulation of Bone Cell Development and Tissue Formation:

Jane B. Lian;Gary S. Stein.
Critical Reviews in Oral Biology & Medicine (1992)

787 Citations

Factors that promote progressive development of the osteoblast phenotype in cultured fetal rat calvaria cells.

Michael A. Aronow;Louis C. Gerstenfeld;Thomas A. Owen;Melissa S. Tassinari.
Journal of Cellular Physiology (1990)

659 Citations

A microRNA signature for a BMP2-induced osteoblast lineage commitment program.

Zhaoyong Li;Mohammad Q. Hassan;Stefano Volinia;Andre J. van Wijnen.
Proceedings of the National Academy of Sciences of the United States of America (2008)

639 Citations

Biological Functions of miR-29b Contribute to Positive Regulation of Osteoblast Differentiation

Zhaoyong Li;Mohammad Q. Hassan;Mohammed Jafferji;Rami I. Aqeilan.
Journal of Biological Chemistry (2009)

634 Citations

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