D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 64 Citations 19,661 150 World Ranking 4246 National Ranking 283

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Gene expression

His primary areas of investigation include Osteoblast, Cell biology, RUNX2, Chondrocyte and Internal medicine. His Osteoblast study incorporates themes from Cell culture, Cell migration, Osteopontin, Molecular biology and Extracellular matrix. His research in RUNX2 intersects with topics in Pathogenesis, Mesenchymal stem cell, Cellular differentiation and Anatomy.

His Chondrocyte research includes themes of Chondrogenesis, Transcription factor and Endochondral ossification. The various areas that Toshihisa Komori examines in his Endochondral ossification study include Sp7 Transcription Factor and Intramembranous ossification. His work deals with themes such as Ossification, Endocrinology and Messenger RNA, which intersect with Internal medicine.

His most cited work include:

  • Targeted Disruption of Cbfa1 Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts (3635 citations)
  • Pathogenic Significance of Interleukin-6 (IL-6/BSF-2) in Castleman's Disease (743 citations)
  • Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12. (741 citations)

What are the main themes of his work throughout his whole career to date?

Toshihisa Komori mainly investigates Cell biology, Osteoblast, Internal medicine, Endocrinology and Chondrocyte. His Cell biology research incorporates elements of DMP1, Transcription factor and Immunology. His Osteoblast study combines topics from a wide range of disciplines, such as Osteocalcin, Osteopontin, Bone morphogenetic protein and Cellular differentiation.

He combines subjects such as Osteocyte and Messenger RNA with his study of Internal medicine. His work deals with themes such as Phenotype, Bone regeneration, Bone morphogenetic protein 7 and Bone marrow, which intersect with Endocrinology. Toshihisa Komori works mostly in the field of Chondrocyte, limiting it down to topics relating to Endochondral ossification and, in certain cases, Intramembranous ossification and Ossification.

He most often published in these fields:

  • Cell biology (52.08%)
  • Osteoblast (44.79%)
  • Internal medicine (34.90%)

What were the highlights of his more recent work (between 2013-2021)?

  • Cell biology (52.08%)
  • Osteoblast (44.79%)
  • Chondrocyte (30.73%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Cell biology, Osteoblast, Chondrocyte, RUNX2 and Internal medicine. His studies deal with areas such as Osteocyte, Transcription factor and Gene expression as well as Cell biology. His biological study spans a wide range of topics, including Angiogenesis, Apoptosis, Downregulation and upregulation, Immunology and Bone tissue.

His Chondrocyte research includes themes of Cancer research, Bioinformatics, Enhancer, Molecular biology and Endochondral ossification. His RUNX2 study integrates concerns from other disciplines, such as Pathology, Morphogenesis, Cartilage and DLX5. His Internal medicine research incorporates themes from Osteocalcin and Endocrinology.

Between 2013 and 2021, his most popular works were:

  • Runx2, an inducer of osteoblast and chondrocyte differentiation (107 citations)
  • Animal models for osteoporosis. (106 citations)
  • Regulation of Proliferation, Differentiation and Functions of Osteoblasts by Runx2. (97 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Gene expression

His scientific interests lie mostly in Cell biology, Osteoblast, RUNX2, Chondrocyte and Wnt signaling pathway. The concepts of his Cell biology study are interwoven with issues in Molecular biology, Gene knockdown and Autophagy-Related Protein 7. His research in Osteoblast intersects with topics in Apoptosis, Cancer research, Internal medicine and RANKL.

His research links Osteocalcin with Internal medicine. Toshihisa Komori interconnects Andrology, Bone morphogenetic protein and Incisor in the investigation of issues within RUNX2. His Chondrocyte research includes elements of Enhancer, Mef2, Enhanceosome, Endochondral ossification and Mesenchymal stem cell.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Targeted Disruption of Cbfa1 Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts

T Komori;H Yagi;S Nomura;A Yamaguchi.
Cell (1997)

4785 Citations

Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12.

Kyeong-Sook Lee;Hyun-Jung Kim;Qing-Lin Li;Xin-Zi Chi.
Molecular and Cellular Biology (2000)

1162 Citations

Regulation of osteoblast differentiation by transcription factors

Toshihisa Komori.
Journal of Cellular Biochemistry (2006)

1094 Citations

Pathogenic Significance of Interleukin-6 (IL-6/BSF-2) in Castleman's Disease

K Yoshizaki;T Matsuda;N Nishimoto;T Kuritani.
Blood (1989)

1082 Citations

Regulation of osteoblast differentiation mediated by bone morphogenetic proteins, hedgehogs, and Cbfa1.

Akira Yamaguchi;Toshihisa Komori;Tatsuo Suda.
Endocrine Reviews (2000)

962 Citations

Differential Requirements for Runx Proteins in CD4 Repression and Epigenetic Silencing during T Lymphocyte Development

Ichiro Taniuchi;Motomi Osato;Takeshi Egawa;Mary Jean Sunshine.
Cell (2002)

793 Citations

Regulation of bone development and extracellular matrix protein genes by RUNX2.

Toshihisa Komori.
Cell and Tissue Research (2010)

782 Citations

Maturational disturbance of chondrocytes in Cbfa1-deficient mice.

Masahiko Inada;Takahiro Yasui;Takahiro Yasui;Shintaro Nomura;Seigou Miyake.
Developmental Dynamics (1999)

756 Citations

Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog

Carolina A. Yoshida;Hiromitsu Yamamoto;Takashi Fujita;Tatsuya Furuichi.
Genes & Development (2004)

587 Citations

Cbfa1 isoforms exert functional differences in osteoblast differentiation.

Hideyuki Harada;Shuzo Tagashira;Masanori Fujiwara;Shinji Ogawa.
Journal of Biological Chemistry (1999)

567 Citations

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