D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 65 Citations 21,979 191 World Ranking 4006 National Ranking 263

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Cancer

His main research concerns Internal medicine, Endocrinology, Osteoblast, Cell biology and Cellular differentiation. As a part of the same scientific family, Akira Yamaguchi mostly works in the field of Internal medicine, focusing on Osteocalcin and, on occasion, Osteopontin. His studies in Endocrinology integrate themes in fields like Spleen, Multinucleate and Receptor.

His work carried out in the field of Osteoblast brings together such families of science as Type I collagen, Adipocyte, Core binding factor and Transfection. In his study, which falls under the umbrella issue of Cell biology, Anatomy is strongly linked to P19 cell. The study incorporates disciplines such as Cell culture, Myogenesis, Molecular biology, Bone morphogenetic protein 2 and Bone morphogenetic protein in addition to Cellular differentiation.

His most cited work include:

  • Targeted Disruption of Cbfa1 Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts (3635 citations)
  • Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage. (1316 citations)
  • Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction (1124 citations)

What are the main themes of his work throughout his whole career to date?

Akira Yamaguchi mainly focuses on Internal medicine, Endocrinology, Osteoblast, Cell biology and Pathology. His Internal medicine study frequently draws connections to other fields, such as Cortical bone. His Endocrinology study combines topics in areas such as Parathyroid hormone, Calcium and Receptor.

He interconnects Osteocalcin, Molecular biology, Cellular differentiation and Bone morphogenetic protein 2 in the investigation of issues within Osteoblast. Akira Yamaguchi has researched Osteocalcin in several fields, including Cell culture and Osteopontin. His research in Cell biology intersects with topics in Transcription factor, Bone morphogenetic protein and Downregulation and upregulation.

He most often published in these fields:

  • Internal medicine (29.39%)
  • Endocrinology (26.84%)
  • Osteoblast (24.28%)

What were the highlights of his more recent work (between 2012-2021)?

  • Pathology (23.64%)
  • Cell biology (23.96%)
  • Osteoblast (24.28%)

In recent papers he was focusing on the following fields of study:

Akira Yamaguchi spends much of his time researching Pathology, Cell biology, Osteoblast, Cell culture and Bone resorption. His studies deal with areas such as Osteocyte, Downregulation and upregulation, ALPL and Transcription factor as well as Cell biology. His work deals with themes such as Osteocalcin, Mesenchymal stem cell, Bone regeneration and Parathyroid hormone, which intersect with Osteoblast.

Akira Yamaguchi combines subjects such as Cancer cell, Molecular biology and Mouth neoplasm with his study of Cell culture. His Bone resorption study falls within the topics of Endocrinology and Internal medicine. The Endocrinology study combines topics in areas such as Cortical bone and Virus.

Between 2012 and 2021, his most popular works were:

  • The Role of Osteocytes in Bone Resorption during Orthodontic Tooth Movement (45 citations)
  • Functional tooth restoration by next-generation bio-hybrid implant as a bio-hybrid artificial organ replacement therapy (44 citations)
  • THBS1 is induced by TGFB1 in the cancer stroma and promotes invasion of oral squamous cell carcinoma. (38 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Cancer

His primary areas of study are Pathology, Tumor microenvironment, Mouth neoplasm, Cell growth and Cancer cell. His Pathology research incorporates elements of Tissue engineering, Cancer, Regenerative medicine and Tooth eruption. His study in Tumor microenvironment is interdisciplinary in nature, drawing from both Angiogenesis, Neovascularization, Tube formation and Notch signaling pathway.

His Cancer cell research integrates issues from Cell culture, Stromal cell, Cadherin and Cellular differentiation. His Cell culture study combines topics from a wide range of disciplines, such as Endocrinology, Internal medicine, Bone resorption and RANKL. His research on Stromal cell also deals with topics like

  • Cell biology and related Downregulation and upregulation,
  • Denosumab which is related to area like Transplantation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Targeted Disruption of Cbfa1 Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts

T Komori;H Yagi;S Nomura;A Yamaguchi.
Cell (1997)

4785 Citations

Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage.

T Katagiri;A Yamaguchi;M Komaki;E Abe.
Journal of Cell Biology (1994)

1679 Citations

Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction

Kojiro Sato;Ayako Suematsu;Kazuo Okamoto;Akira Yamaguchi.
Journal of Experimental Medicine (2006)

1508 Citations

IL-6 is produced by osteoblasts and induces bone resorption.

Y Ishimi;C Miyaura;C H Jin;T Akatsu.
Journal of Immunology (1990)

1311 Citations

OSTEOBLASTIC CELLS ARE INVOLVED IN OSTEOCLAST FORMATION

N Takahashi;T Akatsu;N Udagawa;T Sasaki.
Endocrinology (1988)

1139 Citations

Regulation of osteoblast differentiation mediated by bone morphogenetic proteins, hedgehogs, and Cbfa1.

Akira Yamaguchi;Toshihisa Komori;Tatsuo Suda.
Endocrine Reviews (2000)

962 Citations

Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro.

A Yamaguchi;T Katagiri;T Ikeda;J M Wozney.
Journal of Cell Biology (1991)

860 Citations

Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation

Shigeru Kotake;Kazuto Sato;Kang Jung Kim;Naoyuki Takahashi.
Journal of Bone and Mineral Research (2009)

619 Citations

The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2.

Takenobu Katagiri;Akira Yamaguchi;Tohru Ikeda;Shusaku Yoshiki.
Biochemical and Biophysical Research Communications (1990)

596 Citations

Cbfa1 isoforms exert functional differences in osteoblast differentiation.

Hideyuki Harada;Shuzo Tagashira;Masanori Fujiwara;Shinji Ogawa.
Journal of Biological Chemistry (1999)

567 Citations

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