His main research concerns Internal medicine, Endocrinology, Osteoblast, Cell biology and Cellular differentiation. As a part of the same scientific family, Akira Yamaguchi mostly works in the field of Internal medicine, focusing on Osteocalcin and, on occasion, Osteopontin. His studies in Endocrinology integrate themes in fields like Spleen, Multinucleate and Receptor.
His work carried out in the field of Osteoblast brings together such families of science as Type I collagen, Adipocyte, Core binding factor and Transfection. In his study, which falls under the umbrella issue of Cell biology, Anatomy is strongly linked to P19 cell. The study incorporates disciplines such as Cell culture, Myogenesis, Molecular biology, Bone morphogenetic protein 2 and Bone morphogenetic protein in addition to Cellular differentiation.
Akira Yamaguchi mainly focuses on Internal medicine, Endocrinology, Osteoblast, Cell biology and Pathology. His Internal medicine study frequently draws connections to other fields, such as Cortical bone. His Endocrinology study combines topics in areas such as Parathyroid hormone, Calcium and Receptor.
He interconnects Osteocalcin, Molecular biology, Cellular differentiation and Bone morphogenetic protein 2 in the investigation of issues within Osteoblast. Akira Yamaguchi has researched Osteocalcin in several fields, including Cell culture and Osteopontin. His research in Cell biology intersects with topics in Transcription factor, Bone morphogenetic protein and Downregulation and upregulation.
Akira Yamaguchi spends much of his time researching Pathology, Cell biology, Osteoblast, Cell culture and Bone resorption. His studies deal with areas such as Osteocyte, Downregulation and upregulation, ALPL and Transcription factor as well as Cell biology. His work deals with themes such as Osteocalcin, Mesenchymal stem cell, Bone regeneration and Parathyroid hormone, which intersect with Osteoblast.
Akira Yamaguchi combines subjects such as Cancer cell, Molecular biology and Mouth neoplasm with his study of Cell culture. His Bone resorption study falls within the topics of Endocrinology and Internal medicine. The Endocrinology study combines topics in areas such as Cortical bone and Virus.
His primary areas of study are Pathology, Tumor microenvironment, Mouth neoplasm, Cell growth and Cancer cell. His Pathology research incorporates elements of Tissue engineering, Cancer, Regenerative medicine and Tooth eruption. His study in Tumor microenvironment is interdisciplinary in nature, drawing from both Angiogenesis, Neovascularization, Tube formation and Notch signaling pathway.
His Cancer cell research integrates issues from Cell culture, Stromal cell, Cadherin and Cellular differentiation. His Cell culture study combines topics from a wide range of disciplines, such as Endocrinology, Internal medicine, Bone resorption and RANKL. His research on Stromal cell also deals with topics like
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Targeted Disruption of Cbfa1 Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts
T Komori;H Yagi;S Nomura;A Yamaguchi.
Cell (1997)
Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage.
T Katagiri;A Yamaguchi;M Komaki;E Abe.
Journal of Cell Biology (1994)
Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
Kojiro Sato;Ayako Suematsu;Kazuo Okamoto;Akira Yamaguchi.
Journal of Experimental Medicine (2006)
IL-6 is produced by osteoblasts and induces bone resorption.
Y Ishimi;C Miyaura;C H Jin;T Akatsu.
Journal of Immunology (1990)
OSTEOBLASTIC CELLS ARE INVOLVED IN OSTEOCLAST FORMATION
N Takahashi;T Akatsu;N Udagawa;T Sasaki.
Endocrinology (1988)
Regulation of osteoblast differentiation mediated by bone morphogenetic proteins, hedgehogs, and Cbfa1.
Akira Yamaguchi;Toshihisa Komori;Tatsuo Suda.
Endocrine Reviews (2000)
Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro.
A Yamaguchi;T Katagiri;T Ikeda;J M Wozney.
Journal of Cell Biology (1991)
Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation
Shigeru Kotake;Kazuto Sato;Kang Jung Kim;Naoyuki Takahashi.
Journal of Bone and Mineral Research (2009)
The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2.
Takenobu Katagiri;Akira Yamaguchi;Tohru Ikeda;Shusaku Yoshiki.
Biochemical and Biophysical Research Communications (1990)
Cbfa1 isoforms exert functional differences in osteoblast differentiation.
Hideyuki Harada;Shuzo Tagashira;Masanori Fujiwara;Shinji Ogawa.
Journal of Biological Chemistry (1999)
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