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Medicine

D-Index
96
Citations
47903
World Ranking
9499
National Ranking
259

Overview

Naoyuki Takahashi is affiliated with Matsumoto Dental University in Japan. Their research spans the fields of Medicine and Engineering, with particular emphasis on Molecular Biology, Organic Chemistry, Immunology, Electrical and Electronic Engineering, and Pathology and Forensic Medicine.

The main topics of their work include Vitamin D Research Studies, Bone health and treatments, Parathyroid Disorders and Treatments, Bone Metabolism and Diseases, Cell Adhesion Molecules Research, Angiogenesis and VEGF in Cancer, and Cancer, Hypoxia, and Metabolism.

Naoyuki Takahashi has contributed to several scientific publications. Notable recent papers include:

  • The Vitamin D Receptor in Osteoblast-Lineage Cells Is Essential for the Proresorptive Activity of 1α,25(OH)2D3 In Vivo (2020, Endocrinology)
  • Sclerostin expression in trabecular bone is downregulated by osteoclasts (2020, Scientific Reports)
  • Myeloid immune checkpoint ILT3/LILRB4/gp49B can co-tether fibronectin with integrin on macrophages (2022, International Immunology)
  • Microfluidic platform for the reproduction of hypoxic vascular microenvironments (2023, Scientific Reports)
  • P21-activated kinase regulates oxygen-dependent migration of vascular endothelial cells in monolayers (2021, Cell Adhesion & Migration)

Their work has been published frequently in venues such as IET Conference Proceedings, Scientific Reports, Endocrinology, International Immunology, and The Journal of Steroid Biochemistry and Molecular Biology.

Naoyuki Takahashi has collaborated extensively with several researchers, including Nobuyuki Udagawa, Hisataka Yasuda, Yuko Nakamichi, Daisuke Yoshino, and Kenichi Funamoto.

Best Publications

  • Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

    Hisataka Yasuda;Nobuyuki Shima;Nobuaki Nakagawa;Kyoji Yamaguchi

  • Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families.

    T. Suda;N. Takahashi;N. Udagawa;E. Jimi

  • IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis

    Shigeru Kotake;Nobuyuki Udagawa;Naoyuki Takahashi;Kenichiro Matsuzaki

  • Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage.

    T Katagiri;A Yamaguchi;M Komaki;E Abe

  • Tumor Necrosis Factor α Stimulates Osteoclast Differentiation by a Mechanism Independent of the Odf/Rankl–Rank Interaction

    Kanichiro Kobayashi;Naoyuki Takahashi;Eijiro Jimi;Nobuyuki Udagawa

  • Modulation of Osteoclast Differentiation

    T Suda;N Takahashi;T J Martin

  • Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells.

    N Udagawa;N Takahashi;T Akatsu;H Tanaka

  • Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6.

    T Tamura;N Udagawa;N Takahashi;C Miyaura

  • OSTEOBLASTIC CELLS ARE INVOLVED IN OSTEOCLAST FORMATION

    N Takahashi;T Akatsu;N Udagawa;T Sasaki

  • Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures.

    N Takahashi;H Yamana;S Yoshiki;G D Roodman

  • Regulatory mechanisms of osteoblast and osteoclast differentiation.

    T Katagiri;N Takahashi

  • A new member of tumor necrosis factor ligand family, ODF/OPGL/TRANCE/RANKL, regulates osteoclast differentiation and function.

    Naoyuki Takahashi;Nobuyuki Udagawa;Tatsuo Suda

  • Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors.

    S Tanaka;N Takahashi;N Udagawa;T Tamura

  • Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation

    Shigeru Kotake;Kazuto Sato;Kang Jung Kim;Naoyuki Takahashi

  • Activated human T cells directly induce osteoclastogenesis from human monocytes: possible role of T cells in bone destruction in rheumatoid arthritis patients.

    Shigeru Kotake;Nobuyuki Udagawa;Masayuki Hakoda;Makio Mogi

  • Osteoclast Differentiation Factor Acts as a Multifunctional Regulator in Murine Osteoclast Differentiation and Function

    Eijiro Jimi;Shuichi Akiyama;Taro Tsurukai;Nobuo Okahashi

  • The bone marrow-derived stromal cell lines MC3T3-G2/PA6 and ST2 support osteoclast-like cell differentiation in cocultures with mouse spleen cells.

    Nobuyuki Udagawa;Naoyuki Takahashi;Takuhiko Akatsu;Takahisa Sasaki

  • Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis

    Kazuhiro Maeda;Yasuhiro Kobayashi;Nobuyuki Udagawa;Shunsuke Uehara

  • Osteoprotegerin produced by osteoblasts is an important regulator in osteoclast development and function.

    Nobuyuki Udagawa;Naoyuki Takahashi;Hisataka Yasuda;Atsuko Mizuno

  • Osteoblasts/stromal cells stimulate osteoclast activation through expression of osteoclast differentiation factor/RANKL but not macrophage colony-stimulating factor

    N. Udagawa;N. Takahashi;Eijiro Jimi;K. Matsuzaki

Frequent Co-Authors

Nobuyuki Udagawa
Nobuyuki Udagawa Matsumoto Dental University
Tatsuo Suda
Tatsuo Suda Saitama Medical University
Sakae Tanaka
Sakae Tanaka University of Tokyo
Akira Yamaguchi
Akira Yamaguchi Tokyo Dental College
Josef M. Penninger
Josef M. Penninger University of British Columbia
T. John Martin
T. John Martin St Vincents Institute of Medical Research
Shigeaki Kato
Shigeaki Kato University of Tokyo
Kazuo Nagai
Kazuo Nagai Chubu University
Matthew T. Gillespie
Matthew T. Gillespie Monash University
Hiroyuki Kato
Hiroyuki Kato Massachusetts General Hospital

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