His primary scientific interests are in Osteoclast, Internal medicine, Endocrinology, RANKL and Cell biology. The Osteoclast study combines topics in areas such as Tumor necrosis factor alpha, Cancer research, Osteolysis, Proto-oncogene tyrosine-protein kinase Src and Bone resorption. His Cancer research study incorporates themes from NF-κB and c-jun.
His research in Bone resorption intersects with topics in Integrin alphaVbeta3, Osteoprotegerin, Bone remodeling and Syk. His RANKL research integrates issues from Bone density, Macrophage colony-stimulating factor and Cytokine. His work carried out in the field of Cell biology brings together such families of science as Receptor, Bone marrow and Osteoblast.
F. Patrick Ross mainly focuses on Osteoclast, Cell biology, Internal medicine, Endocrinology and Bone resorption. His biological study spans a wide range of topics, including Activator, RANKL, Cancer research and Immunology. His RANKL study combines topics in areas such as Macrophage colony-stimulating factor, Cytokine, Signal transduction and Cellular differentiation.
His Cell biology research includes themes of Integrin, Biochemistry, Bone marrow and Cytoskeleton. The study incorporates disciplines such as Cell and Osteoblast in addition to Endocrinology. In his study, which falls under the umbrella issue of Bone resorption, Cathepsin is strongly linked to Cathepsin K.
Osteoclast, Cell biology, Internal medicine, Bone resorption and Endocrinology are his primary areas of study. His Osteoclast research incorporates elements of Cancer research, Cellular differentiation, RANKL, Immunology and Cytoskeleton. His Cancer research study integrates concerns from other disciplines, such as Activator, Autocrine signalling, Osteolysis and Osteoclast proliferation.
As part of the same scientific family, F. Patrick Ross usually focuses on Cell biology, concentrating on Bone marrow and intersecting with RNA and Gene expression. He has researched Bone resorption in several fields, including Osteopetrosis, Biochemistry, Small GTPase, Integrin and Microphthalmia-associated transcription factor. F. Patrick Ross interconnects Cancellous bone and Osteoblast in the investigation of issues within Endocrinology.
His primary areas of study are Osteoclast, Bone resorption, Osteoporosis, Cell biology and Internal medicine. F. Patrick Ross works mostly in the field of Osteoclast, limiting it down to topics relating to Immunology and, in certain cases, Caspase and Homeostasis. His Bone resorption research is multidisciplinary, incorporating perspectives in Osteopetrosis, Cancer research, Cathepsin, Secretion and Acid phosphatase.
His Cell biology research includes elements of Cathepsin D, Lysosome and Cathepsin K. The various areas that he examines in his Internal medicine study include Endocrinology and Osteoblast. F. Patrick Ross combines subjects such as Hematology and Reactive oxygen species with his study of Endocrinology.
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Genetic regulation of osteoclast development and function
Steven L. Teitelbaum;F. Patrick Ross.
Nature Reviews Genetics (2003)
TNF-α induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand
Jonathan Lam;Sunao Takeshita;Jane E. Barker;Osami Kanagawa.
Journal of Clinical Investigation (2000)
β3-integrin–deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival
Kairbaan M. Hodivala-Dilke;Kevin P. McHugh;Dimitrios A. Tsakiris;Helen Rayburn.
Journal of Clinical Investigation (1999)
IL-1 mediates TNF-induced osteoclastogenesis
Shi Wei;Hideki Kitaura;Ping Zhou;F. Patrick Ross.
Journal of Clinical Investigation (2005)
Mice lacking β3 integrins are osteosclerotic because of dysfunctional osteoclasts
Kevin P. McHugh;Kairbaan Hodivala-Dilke;Ming-Hao Zheng;Noriyuki Namba.
Journal of Clinical Investigation (2000)
Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation.
Matthew J Hilton;Xiaolin Tu;Ximei Wu;Shuting Bai.
Nature Medicine (2008)
G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow
Craig L. Semerad;Matthew J. Christopher;Fulu Liu;Brenton Short.
Blood (2005)
Tumor Necrosis Factor-α Mediates Orthopedic Implant Osteolysis
Kurt D. Merkel;Jeanne M. Erdmann;Kevin P. McHugh;Yousef Abu-Amer.
American Journal of Pathology (1999)
Estrogen Decreases Osteoclast Formation by Down-regulating Receptor Activator of NF-κB Ligand (RANKL)-induced JNK Activation
Sunil Srivastava;Gianluca Toraldo;M. Neale Weitzmann;Simone Cenci.
Journal of Biological Chemistry (2001)
Glucocorticoids suppress bone formation via the osteoclast
Hyun Ju Kim;Haibo Zhao;Hideki Kitaura;Sandip Bhattacharyya.
Journal of Clinical Investigation (2006)
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