F. Patrick Ross

Overview

Best Publications

• Genetic regulation of osteoclast development and function

  Steven L. Teitelbaum;F. Patrick Ross

  2332
  Citations

• TNF-α induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand

  Jonathan Lam;Sunao Takeshita;Jane E. Barker;Osami Kanagawa

  1652
  Citations

• β3-integrin–deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival

  Kairbaan M. Hodivala-Dilke;Kevin P. McHugh;Dimitrios A. Tsakiris;Helen Rayburn

  1086
  Citations

• IL-1 mediates TNF-induced osteoclastogenesis

  Shi Wei;Hideki Kitaura;Ping Zhou;F. Patrick Ross

  938
  Citations

• Mice lacking β3 integrins are osteosclerotic because of dysfunctional osteoclasts

  Kevin P. McHugh;Kairbaan Hodivala-Dilke;Ming-Hao Zheng;Noriyuki Namba

  831
  Citations

• Interactions between the bone matrix proteins osteopontin and bone sialoprotein and the osteoclast integrin alpha v beta 3 potentiate bone resorption.

  F. P. Ross;J. Chappel;J. I. Alvarez;D. Sander

  700
  Citations

• Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation.

  Matthew J Hilton;Xiaolin Tu;Ximei Wu;Shuting Bai

  649
  Citations

• G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow

  Craig L. Semerad;Matthew J. Christopher;Fulu Liu;Brenton Short

  602
  Citations

• Recognition of osteopontin and related peptides by an alpha v beta 3 integrin stimulates immediate cell signals in osteoclasts.

  A Miyauchi;J Alvarez;E M Greenfield;A Teti

  579
  Citations

• Tumor Necrosis Factor-α Mediates Orthopedic Implant Osteolysis

  Kurt D. Merkel;Jeanne M. Erdmann;Kevin P. McHugh;Yousef Abu-Amer

  491
  Citations

• Estrogen decreases osteoclast formation by down-regulating receptor activator of NF-kappa B ligand (RANKL)-induced JNK activation.

  Sunil Srivastava;Gianluca Toraldo;M. Neale Weitzmann;Simone Cenci

  465
  Citations

• Glucocorticoids suppress bone formation via the osteoclast

  Hyun Ju Kim;Haibo Zhao;Hideki Kitaura;Sandip Bhattacharyya

  431
  Citations

• αvβ3 and macrophage colony‐stimulating factor: partners in osteoclast biology

  F. Patrick Ross;Steven L. Teitelbaum

  418
  Citations

• Bone loss caused by iron overload in a murine model: importance of oxidative stress.

  Jaime Tsay;Zheiwei Yang;F. Patrick Ross;Susanna Cunningham-Rundles

  406
  Citations

• The IκB Function of NF-κB2 p100 Controls Stimulated Osteoclastogenesis

  Deborah Veis Novack;Li Yin;Amanda Hagen-Stapleton;Robert D. Schreiber

  353
  Citations

• Syk, c-Src, the αvβ3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption

  Wei Zou;Hideki Kitaura;Jennifer Reeve;Fanxin Long

  341
  Citations

• Vav3 regulates osteoclast function and bone mass

  Roberta Faccio;Roberta Faccio;Steven L Teitelbaum;Keiko Fujikawa;Keiko Fujikawa;Jean Chappel

  320
  Citations

• M-CSF mediates TNF-induced inflammatory osteolysis

  Hideki Kitaura;Ping Zhou;Hyun Ju Kim;Deborah V. Novack

  318
  Citations

• Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD

  Sunil Srivastava;M. Neale Weitzmann;Simone Cenci;F. Patrick Ross

  312
  Citations

• SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts.

  Sunao Takeshita;Noriyuki Namba;Noriyuki Namba;Jenny J Zhao;Yebin Jiang

  287
  Citations