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John C. Schimenti

John C. Schimenti

D-Index & Metrics

Genetics

D-Index
70
Citations
15063
World Ranking
2289
National Ranking
1026

Research.com Recognitions

  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

John C. Schimenti is affiliated with Cornell University in the United States. Their research spans across the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a total of 104 and 31 publications in these areas respectively. Their subfields of expertise include Molecular Biology, Genetics, Reproductive Medicine, Public Health, Environmental and Occupational Health, and Cancer Research.

The scientist's work covers a range of topics, notably:

  • CRISPR and Genetic Engineering
  • DNA Repair Mechanisms
  • Pluripotent Stem Cells Research
  • Reproductive Biology and Fertility
  • Renal and related cancers
  • Genomics and Chromatin Dynamics
  • Epigenetics and DNA Methylation

Frequent co-authors include Jordana C. Bloom, Andrea Flesken-Nikitin, Alexander Yu. Nikitin, Priti Singh, and Xinbao Ding, with multiple collaborations ranging from eight to nine joint publications.

Their research has been published across various scientific venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Proceedings of the National Academy of Sciences
  • Reproduction
  • Science Advances

Selected recent papers by John C. Schimenti include:

  • "SKP1 drives the prophase I to metaphase I transition during male meiosis," 2020, Science Advances
  • "Prime editing in mice reveals the essentiality of a single base in driving tissue-specific gene expression," 2021, Genome Biology
  • "Testis formation in XX individuals resulting from novel pathogenic variants in Wilms' tumor 1 (WT1) gene," 2020, Proceedings of the National Academy of Sciences
  • "Oocyte Elimination Through DNA Damage Signaling from CHK1/CHK2 to p53 and p63," 2020, Genetics
  • "A novel function for CDK2 activity at meiotic crossover sites," 2020, PLoS Biology

John C. Schimenti was awarded the status of Fellow of the American Association for the Advancement of Science (AAAS) in 2008.

Best Publications

  • Meiotic prophase arrest with failure of chromosome synapsis in mice deficient for Dmc1, a germline-specific RecA homolog.

    Douglas L. Pittman;John Cobb;Kerry J. Schimenti;Lawriston A. Wilson

  • Mutations in Col4a1 cause perinatal cerebral hemorrhage and porencephaly.

    Douglas B. Gould;F. Campbell Phalan;Guido J. Breedveld;Saskia E. van Mil

  • Genetics of mammalian meiosis: regulation, dynamics and impact on fertility

    Mary Ann Handel;John C. Schimenti

  • A Mouse Speciation Gene Encodes a Meiotic Histone H3 Methyltransferase

    Ondrej Mihola;Zdenek Trachtulec;Cestmir Vlcek;John C. Schimenti

  • An Ancient Transcription Factor Initiates the Burst of piRNA Production during Early Meiosis in Mouse Testes

    Xin Zhiguo Li;Christian K. Roy;Xianjun Dong;Ewelina Bolcun-Filas

  • A Mouse Geneticist’s Practical Guide to CRISPR Applications

    Priti Singh;John C Schimenti;Ewelina Bolcun-Filas

  • A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice

    Naoko Shima;Ana Alcaraz;Ivan Liachko;Tavanna R. Buske

  • Regulating RNA polymerase pausing and transcription elongation in embryonic stem cells

    Irene M. Min;Joshua J. Waterfall;Leighton J. Core;Robert J. Munroe

  • Vestibular defects in head-tilt mice result from mutations in Nox3, encoding an NADPH oxidase

    Rainer Paffenholz;Rebecca A. Bergstrom;Francesca Pasutto;Philipp Wabnitz

  • Reversal of Female Infertility by Chk2 Ablation Reveals the Oocyte DNA Damage Checkpoint Pathway

    Ewelina Bolcun-Filas;Vera D. Rinaldi;Michelle E. White;John C. Schimenti

  • MCM4 mutation causes adrenal failure, short stature, and natural killer cell deficiency in humans

    Claire R. Hughes;Leonardo Guasti;Eirini Meimaridou;Chen-Hua Chuang

  • Evolution of mouse chromosome 17 and the origin of inversions associated with t haplotypes.

    Michael F. Hammer;John Schimenti;Lee M. Silver

  • Mouse Pachytene Checkpoint 2 (Trip13) Is Required for Completing Meiotic Recombination but Not Synapsis

    Xin Chenglin Li;John C Schimenti

  • Chromosomal deletion complexes in mice by radiation of embryonic stem cells

    Yun You;Rebecca Bergstrom;Martina Klemm;Birgit Lederman

  • Positional cloning and characterization of mouse mei8, a disrupted allelle of the meiotic cohesin Rec8.

    Laura A. Bannister;Laura G. Reinholdt;Robert J. Munroe;John C. Schimenti

  • Antagonistic roles of ubiquitin ligase HEI10 and SUMO ligase RNF212 regulate meiotic recombination

    Huanyu Qiao;H B D Prasada Rao;Ye Yang;Jared H Fong

  • Synapsis or silence

    John Schimenti

  • Sequence interpretation. Functional annotation of mouse genome sequences.

    J. H. Nadeau;R. Balling;G. Barsh;D. Beier

  • The mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with Atm.

    Naoko Shima;Robert J. Munroe;John C. Schimenti

  • Identification, characterization, and genetic mapping of Rad51d, a new mouse and human RAD51/RecA-related gene.

    Douglas L. Pittman;Leah Rosa Weinberg;John C. Schimenti

Frequent Co-Authors

Mary Ann Handel
Mary Ann Handel The Jackson Laboratory
John J. Eppig
John J. Eppig Jackson Laboratory
Philipp Kaldis
Philipp Kaldis Lund University
Lee M. Silver
Lee M. Silver Princeton University
Gareth R. Howell
Gareth R. Howell The Jackson Laboratory
Christer Höög
Christer Höög Karolinska Institute
Haiyuan Yu
Haiyuan Yu Cornell University
Dirk G. de Rooij
Dirk G. de Rooij Utrecht University
David R. Liu
David R. Liu Broad Institute
F. Patrick Ross
F. Patrick Ross Hospital for Special Surgery

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