What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Genetics, Meiosis, Molecular biology, Mutation and Synapsis.
Genetics is a component of his Gene, Homologous chromosome, Mutant, Positional cloning and Genome studies.
Specifically, his work in Meiosis is concerned with the study of Chromosomal crossover.
His work deals with themes such as Exome sequencing, DNA damage, DNA repair, DNA Polymerase Theta and Chromosome instability, which intersect with Molecular biology.
His work is dedicated to discovering how DNA damage, Homologous recombination are connected with Oocyte and Cell biology and other disciplines.
The concepts of his Mutation study are interwoven with issues in Zona fasciculata, Adrenal cortex, Adrenal insufficiency and Short stature.
His most cited work include:
- Meiotic prophase arrest with failure of chromosome synapsis in mice deficient for Dmc1, a germline-specific RecA homolog. (502 citations)
- Mutations in Col4a1 cause perinatal cerebral hemorrhage and porencephaly. (369 citations)
- A Mouse Speciation Gene Encodes a Meiotic Histone H3 Methyltransferase (354 citations)
What are the main themes of his work throughout his whole career to date?
John C. Schimenti mostly deals with Genetics, Gene, Cell biology, Meiosis and Mutation.
His study in Genetics concentrates on Allele, Phenotype, Homologous recombination, Mutant and Mutagenesis.
The Cell biology study combines topics in areas such as DNA damage, Genome instability and DNA replication.
His work on Meiosis is being expanded to include thematically relevant topics such as Homologous chromosome.
His Mutation research is multidisciplinary, incorporating elements of Positional cloning, Molecular biology, Germline and Germ cell.
He has researched Molecular biology in several fields, including Chromatin and Stem cell.
He most often published in these fields:
- Genetics (61.05%)
- Gene (30.00%)
- Cell biology (24.21%)
What were the highlights of his more recent work (between 2017-2021)?
- Cell biology (24.21%)
- Gene (30.00%)
- Genetics (61.05%)
In recent papers he was focusing on the following fields of study:
John C. Schimenti mainly focuses on Cell biology, Gene, Genetics, Allele and DNA damage.
His research integrates issues of Synapsis, Meiosis, Mutant, Cyclin-dependent kinase 2 and Germ cell in his study of Cell biology.
John C. Schimenti focuses mostly in the field of Meiosis, narrowing it down to matters related to Homologous recombination and, in some cases, Spermatocyte.
His work investigates the relationship between Gene and topics such as Cancer research that intersect with problems in LGR5 and Organoid.
In his papers, he integrates diverse fields, such as Genetics and Primary ciliary dyskinesia.
His DNA damage research is multidisciplinary, relying on both Mutation, Endogeny and Exogenous DNA.
Between 2017 and 2021, his most popular works were:
- Female-biased embryonic death from inflammation induced by genomic instability (25 citations)
- Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations (17 citations)
- A putative human infertility allele of the meiotic recombinase DMC1 does not affect fertility in mice. (10 citations)
In his most recent research, the most cited papers focused on:
His scientific interests lie mostly in Genetics, Gene, Cell biology, Allele and Mutation.
His work on Homologous chromosome as part of general Genetics study is frequently linked to Testis determining factor, bridging the gap between disciplines.
His studies deal with areas such as Gonad and Wilms' tumor as well as Gene.
John C. Schimenti interconnects Synapsis, Meiosis, Germ cell proliferation and Cyclin-dependent kinase 2 in the investigation of issues within Cell biology.
His study in Allele is interdisciplinary in nature, drawing from both Phenotype, Fertility and Homologous recombination.
He interconnects DNA damage and DNA replication in the investigation of issues within Mutation.
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