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Philipp Kaldis

Philipp Kaldis

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Biology and Biochemistry
Sweden
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
15029
World Ranking
10166
National Ranking
142

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Sweden Leader Award

Overview

Philipp Kaldis is affiliated with Lund University in Sweden and has made contributions primarily in the fields of biochemistry, genetics, and molecular biology, as well as medicine. Their research spans various subfields including molecular biology, epidemiology, oncology, cell biology, and hepatology.

Their recent scholarly output includes multiple publications addressing complex biological and medical topics. Some notable papers are:

  • Pathophysiology of type 2 diabetes and the impact of altered metabolic interorgan crosstalk, 2021, FEBS Journal
  • Therapeutic targeting of the mitochondrial one-carbon pathway: perspectives, pitfalls, and potential, 2021, Oncogene
  • Cell cycle regulation in NAFLD: when imbalanced metabolism limits cell division, 2020, Hepatology International
  • Less-well known functions of cyclin/CDK complexes, 2020, Seminars in Cell and Developmental Biology
  • PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis, 2020, Nature Communications

Kaldis's research topics focus heavily on molecular mechanisms related to cancer and liver diseases. Main topics covered include:

  • RNA modifications and cancer
  • Cancer-related Molecular Pathways
  • DNA Repair Mechanisms
  • Microtubule and mitosis dynamics
  • Liver Disease Diagnosis and Treatment
  • Liver physiology and pathology
  • Epigenetics and DNA Methylation

The scientist frequently publishes in specific venues that include:

  • Frontiers in Cell and Developmental Biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • FEBS Journal
  • Oncogene

Collaboration plays a significant role in their work. Frequent coauthors include:

  • Li Na Zhao
  • Jin Rong Ow
  • Matias J. Caldez
  • Nathan Palmer
  • Heike Wollmann

Philipp Kaldis's research addresses significant challenges at the intersection of metabolism, cancer biology, and liver disease, utilizing molecular and cellular biology techniques to explore regulatory pathways and potential therapeutic targets.

Best Publications

  • Cdks, cyclins and CKIs: roles beyond cell cycle regulation

    Shuhui Lim;Philipp Kaldis;Philipp Kaldis

  • Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms.

    A Satyanarayana;P Kaldis

  • Cdk2 knockout mice are viable.

    Cyril Berthet;Eiman Aleem;Vincenzo Coppola;Lino Tessarollo

  • Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis

    Wen Cai Zhang;Ng Shyh-Chang;He Yang;Amit Rai

  • Cdc2–cyclin E complexes regulate the G1/S phase transition

    Eiman Aleem;Hiroaki Kiyokawa;Philipp Kaldis

  • Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration

    M. Kasim Diril;Chandrahas Koumar Ratnacaram;V. C. Padmakumar;Tiehua Du

  • THE CDK-ACTIVATING KINASE (CAK) : FROM YEAST TO MAMMALS

    P. Kaldis

  • Loss of centrosome integrity induces p38-p53-p21-dependent G1-S arrest.

    Keith Mikule;Benedicte Delaval;Philipp Kaldis;Agata Jurcyzk

  • The Cdk-Activating Kinase (CAK) from Budding Yeast

    Philipp Kaldis;Ann Sutton;Mark J Solomon

  • Combined Loss of Cdk2 and Cdk4 Results in Embryonic Lethality and Rb Hypophosphorylation

    Cyril Berthet;Kimberly D. Klarmann;Mary Beth Hilton;Hyung Chan Suh

  • Kinase-independent function of cyclin E.

    Yan Geng;Young Mi Lee;Markus Welcker;Jherek Swanger

  • Thermal proximity coaggregation for system-wide profiling of protein complex dynamics in cells

    Chris Soon Heng Tan;Ka Diam Go;Xavier Bisteau;Lingyun Dai

  • Dephosphorylation of cyclin-dependent kinases by type 2C protein phosphatases.

    Aiyang Cheng;Karen E. Ross;Philipp Kaldis;Mark J. Solomon

  • p27kip1 (Cyclin-Dependent Kinase Inhibitor 1B) Controls Ovarian Development by Suppressing Follicle Endowment and Activation and Promoting Follicle Atresia in Mice

    Singareddy Rajareddy;Pradeep Reddy;Chun Du;Lian Liu;Lian Liu

  • p21 Inhibits Cdk1 in the Absence of Cdk2 to Maintain the G1/S Phase DNA Damage Checkpoint

    Ande Satyanarayana;Mary Beth Hilton;Philipp Kaldis

  • Human and yeast cdk-activating kinases (CAKs) display distinct substrate specificities.

    Philipp Kaldis;Alicia A. Russo;Hubert S. Chou;Nikola P. Pavletich

  • Cdk1, but not Cdk2, is the sole Cdk that is essential and sufficient to drive resumption of meiosis in mouse oocytes

    Deepak Adhikari;Wenjing Zheng;Yan Shen;Nagaraju Gorre;Nagaraju Gorre

  • 'Hot spots' of creatine kinase localization in brain: cerebellum, hippocampus and choroid plexus.

    Philipp Kaldis;Wolfram Hemmer;Else Zanolla;David Holtzman

  • The metastasis-associated gene Prl-3 is a p53 target involved in cell-cycle regulation.

    Shashwati Basak;Suzanne B.R. Jacobs;Adam J. Krieg;Navneeta Pathak

  • Dephosphorylation of Human Cyclin-dependent Kinases by Protein Phosphatase Type 2Cα and β2 Isoforms *

    Aiyang Cheng;Philipp Kaldis;Mark J. Solomon

Frequent Co-Authors

Lino Tessarollo
Lino Tessarollo National Institutes of Health
Theo Wallimann
Theo Wallimann ETH Zurich
Pär Nordlund
Pär Nordlund Karolinska Institute
Bing Lim
Bing Lim Thymmune Therapeutics
Ernesto Guccione
Ernesto Guccione Icahn School of Medicine at Mount Sinai
Hiroaki Kiyokawa
Hiroaki Kiyokawa Northwestern University
Vinay Tergaonkar
Vinay Tergaonkar Agency for Science, Technology and Research
Walter Hunziker
Walter Hunziker Agency for Science, Technology and Research
Weiping Han
Weiping Han Institute of Molecular and Cell Biology
Byrappa Venkatesh
Byrappa Venkatesh Agency for Science, Technology and Research

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