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Molecular Biology

D-Index
98
Citations
32598
World Ranking
575
National Ranking
315

Overview

Lino Tessarollo is a researcher affiliated with the National Institutes of Health in the United States. Their work spans multiple scientific disciplines, particularly at the intersection of biochemistry, genetics, molecular biology, medicine, and neuroscience. The primary areas of focus include molecular biology, cellular and molecular neuroscience, immunology, neurology, and hematology.

The scientist's research addresses a range of specialized topics, including RNA research and splicing, RNA modifications and cancer, neuroscience and neuropharmacology, pancreatic function and diabetes, nerve injury and regeneration, axon guidance and neuronal signaling, and acute myeloid leukemia research.

Their recent publications highlight diverse contributions to the biomedical field. Noteworthy papers include:

  • Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants (2021, Nature)
  • Novel metabolic role for BDNF in pancreatic β-cell insulin secretion (2020, Nature Communications)
  • Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans (2020, Cell Reports)
  • TrkB Truncated Isoform Receptors as Transducers and Determinants of BDNF Functions (2022, Frontiers in Neuroscience)
  • PARIS farnesylation prevents neurodegeneration in models of Parkinson's disease (2021, Science Translational Medicine)

Lino Tessarollo has frequently collaborated with a number of coauthors throughout their career. These include Francesco Tomassoni-Ardori, Sudhirkumar Yanpallewar, Gianluca Fulgenzi, Mary Ellen Palko, and Sandra Burkett.

Their studies have been published repeatedly in specific scientific journals and repositories such as Nature Communications, bioRxiv (Cold Spring Harbor Laboratory), Cell Reports, Cell Death and Disease, and Neuro-Oncology.

Best Publications

  • A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA.

    E-Chiang Lee;Daiguan Yu;J. Martinez de Velasco;Lino Tessarollo

  • Genomic instability in mice lacking histone H2AX.

    Arkady Celeste;Simone Petersen;Peter J. Romanienko;Oscar Fernandez-Capetillo

  • Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth.

    Sergei I. Grivennikov;Kepeng Wang;Daniel Mucida;C. Andrew Stewart

  • c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells

    Zuqin Nie;Gangqing Hu;Gang Wei;Kairong Cui

  • Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities.

    W. Ernest Lyons;W. Ernest Lyons;Laura A. Mamounas;George A. Ricaurte;Vincenzo Coppola

  • Cdk2 knockout mice are viable.

    Cyril Berthet;Eiman Aleem;Vincenzo Coppola;Lino Tessarollo

  • Brain-derived neurotrophic factor (BDNF) is required for the enhancement of hippocampal neurogenesis following environmental enrichment

    Chiara Rossi;Andrea Angelucci;Laura Costantin;Chiara Braschi

  • Neuronal release of proBDNF

    Jianmin Yang;Chia-Jen Siao;Guhan Nagappan;Tina Marinic

  • Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs

    Jie Jiang;Jie Jiang;Qiang Zhu;Tania F. Gendron;Shahram Saberi

  • AN ESSENTIAL ROLE FOR C/EBPBETA IN FEMALE REPRODUCTION

    Esta Sterneck;Lino Tessarollo;Peter F. Johnson

  • ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43

    Eveline S. Arnold;Shuo-Chien Ling;Stephanie C. Huelga;Clotilde Lagier-Tourenne

  • Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice

    Jie Zhu;Simone Petersen;Lino Tessarollo;André Nussenzweig

  • Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop.

    Brian R. Stanton;Archibald S. Perkins;Lino Tessarollo;David A. Sassoon

  • BDNF Promotes the Regenerative Sprouting, But Not Survival, of Injured Serotonergic Axons in the Adult Rat Brain

    Laura A. Mamounas;C. Anthony Altar;Mary E. Blue;David R. Kaplan

  • Inactivation of Lrg-47 and Irg-47 Reveals a Family of Interferon γ–Inducible Genes with Essential, Pathogen-Specific Roles in Resistance to Infection

    Carmen M. Collazo;George S. Yap;Gregory D. Sempowski;Kimberly C. Lusby;Kimberly C. Lusby

  • Bcl11a is essential for normal lymphoid development

    Pentao Liu;Jonathan R Keller;Mariaestela Ortiz;Lino Tessarollo

  • Distinct and Nonredundant In Vivo Functions of TNF Produced by T Cells and Macrophages/Neutrophils: Protective and Deleterious Effects

    Sergei I. Grivennikov;Alexei V. Tumanov;Alexei V. Tumanov;Dmitry J. Liepinsh;Andrei A. Kruglov

  • Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation

    A. Jeannine Lincoln;Dineli Wickramasinghe;Paula Stein;Richard M. Schultz

  • Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase.

    Philip C. Wong;Darrel Waggoner;Jamuna R. Subramaniam;Lino Tessarollo

  • A Transposon-Based Genetic Screen in Mice Identifies Genes Altered in Colorectal Cancer

    Timothy K. Starr;Raha Allaei;Kevin A. T. Silverstein;Rodney A. Staggs

Frequent Co-Authors

Nancy A. Jenkins
Nancy A. Jenkins The University of Texas MD Anderson Cancer Center
Neal G. Copeland
Neal G. Copeland The University of Texas MD Anderson Cancer Center
Philipp Kaldis
Philipp Kaldis Lund University
Luis F. Parada
Luis F. Parada Memorial Sloan Kettering Cancer Center
Don W. Cleveland
Don W. Cleveland University of California, San Diego
Wanghua Gong
Wanghua Gong Leidos (United States)
Ji Ming Wang
Ji Ming Wang National Institutes of Health
Clotilde Lagier-Tourenne
Clotilde Lagier-Tourenne Harvard University
Yingying Le
Yingying Le Chinese Academy of Sciences
Christopher Shaw
Christopher Shaw King's College London

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