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Genetics

D-Index
119
Citations
63645
World Ranking
388
National Ranking
66

Research.com Recognitions

  • 2018 - Member of the National Academy of Sciences
  • 2017 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2015 - Nobel Prize for mechanistic studies of DNA repair
  • 1989 - Member of Academia Europaea
  • 1988 - Fellow of the Royal Society, United Kingdom

Overview

Tomas Lindahl is affiliated with The Francis Crick Institute in the United Kingdom. Their primary field of study is Medicine, with a specific focus on Cardiology and Cardiovascular Medicine, Internal Medicine, Surgery, Nutrition and Dietetics, and Pulmonary and Respiratory Medicine.

Their research covers several main topics including:

  • Venous Thromboembolism Diagnosis and Management
  • Blood properties and coagulation
  • Acute Myocardial Infarction Research
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Selenium in Biological Systems
  • Trace Elements in Health
  • Trauma, Hemostasis, Coagulopathy, Resuscitation

Tomas Lindahl has published in a variety of scientific journals. Frequent publication venues include:

  • Platelets
  • Nutrients
  • Thrombosis Research
  • Journal of Thrombosis and Haemostasis
  • Frontiers in Cardiovascular Medicine

Their recent papers highlight research in cardiovascular and blood-related health issues:

  • "Dietary Supplementation with Selenium and Coenzyme Q10 Prevents Increase in Plasma D-Dimer While Lowering Cardiovascular Mortality in an Elderly Swedish Population," 2021, Nutrients
  • "Associations between hemostatic markers and mortality in COVID-19 - Compounding effects of D-dimer, antithrombin and PAP complex," 2022, Thrombosis Research
  • "Unveiling the complex effects of direct oral anticoagulants on dilute Russell's viper venom time assays," 2020, Journal of Thrombosis and Haemostasis
  • "Significant decrease of von Willebrand factor and plasminogen activator inhibitor-1 by providing supplementation with selenium and coenzyme Q10 to an elderly population with a low selenium status," 2020, European Journal of Nutrition
  • "Effects of Heparin and Bivalirudin on Thrombin-Induced Platelet Activation: Differential Modulation of PAR Signaling Drives Divergent Prothrombotic Responses," 2021, Frontiers in Cardiovascular Medicine

Frequent collaborators in their research include:

  • Joakim Alfredsson
  • Urban Alehagen
  • Niklas Boknäs
  • Ankit S. Macwan
  • Kerstin M. Gustafsson

Tomas Lindahl has received several recognitions, including:

  • Member of the National Academy of Sciences (2018)
  • Fellow of the American Association for the Advancement of Science (AAAS) (2017)
  • Nobel Prize (2015) for mechanistic studies of DNA repair
  • Member of Academia Europaea (1989)
  • Fellow of the Royal Society, United Kingdom (1988)

Best Publications

  • Instability and decay of the primary structure of DNA

    Tomas Lindahl

  • N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO.

    Guifang Jia;Ye Fu;Xu Zhao;Xu Zhao;Qing Dai

  • Rate of depurination of native deoxyribonucleic acid.

    Tomas Lindahl;Barbro Nyberg

  • Quality control by DNA repair.

    Tomas Lindahl;Richard D. Wood

  • The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate–Dependent Nucleic Acid Demethylase

    Thomas Gerken;Christophe A. Girard;Yi-Chun Loraine Tung;Celia J. Webby

  • Human DNA Repair Genes

    Richard D. Wood;Michael Mitchell;John Sgouros;Tomas Lindahl

  • Role of poly(ADP-ribose) formation in DNA repair

    Masahiko S. Satoh;Tomas Lindahl

  • ACCUMULATION OF PREMUTAGENIC DNA LESIONS IN MICE DEFECTIVE IN REMOVAL OF OXIDATIVE BASE DAMAGE

    Arne Klungland;Ian Rosewell;Stephan Hollenbach;Elisabeth Larsen

  • Second pathway for completion of human DNA base excision‐repair: reconstitution with purified proteins and requirement for DNase IV (FEN1)

    Arne Klungland;Tomas Lindahl

  • Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein.

    Y Kubota;R A Nash;A Klungland;P Schär

  • Heat-induced deamination of cytosine residues in deoxyribonucleic acid

    Tomas Lindahl;Barbro Nyberg

  • Repair and Genetic Consequences of Endogenous DNA Base Damage in Mammalian Cells

    Deborah E. Barnes;Tomas Lindahl

  • Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus.

    Yanick J Crow;Yanick J Crow;Bruce E Hayward;Rekha Parmar;Peter Robins

  • Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage

    Sarah C. Trewick;Timothy F. Henshaw;Robert P. Hausinger;Tomas Lindahl

  • Regulation and expression of the adaptive response to alkylating agents.

    Tomas Lindahl;Barbara Sedgwick;Mutsuo Sekiguchi;Yusaku Nakabeppu

  • Rate of chain breakage at apurinic sites in double-stranded deoxyribonucleic acid.

    Tomas Lindahl;Annika Andersson

  • Immunoglobulin Isotype Switching Is Inhibited and Somatic Hypermutation Perturbed in UNG-Deficient Mice

    Cristina Rada;Gareth T. Williams;Hilde Nilsen;Deborah E Barnes

  • Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks.

    Tomas Lindahl;Masahiko S. Satoh;Guy G. Poirier;Arne Klungland

  • An N-Glycosidase from Escherichia coli That Releases Free Uracil from DNA Containing Deaminated Cytosine Residues

    Tomas Lindahl

  • Repair of endogenous DNA damage

    T Lindahl;D E Barnes

Frequent Co-Authors

Richard D. Wood
Richard D. Wood The University of Texas MD Anderson Cancer Center
George Klein
George Klein Karolinska Institute
Arne Klungland
Arne Klungland Oslo University Hospital
Yun-Gui Yang
Yun-Gui Yang Chinese Academy of Sciences
Yanick J. Crow
Yanick J. Crow Université Paris Cité
Beverly E. Griffin
Beverly E. Griffin Imperial College London
Paul A. Bates
Paul A. Bates The Francis Crick Institute
Alan R. Lehmann
Alan R. Lehmann University of Sussex
Erling Seeberg
Erling Seeberg University of Oslo
Georg W. Bornkamm
Georg W. Bornkamm Technical University of Munich

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