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Yusaku Nakabeppu

Yusaku Nakabeppu

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Genetics and Molecular Biology
Japan
2024

D-Index & Metrics

Molecular Biology

D-Index
86
Citations
24889
World Ranking
826
National Ranking
62

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in Japan Leader Award

Overview

Yusaku Nakabeppu is affiliated with Kyushu University in Japan and conducts research primarily within biochemistry, genetics, and molecular biology, with significant work also spanning medicine. Their scholarly output includes 41 publications focused on biochemistry, genetics, and molecular biology, alongside 30 publications in medicine.

Their research encompasses several subfields of study:

  • Molecular Biology
  • Physiology
  • Pathology and Forensic Medicine
  • Cancer Research
  • Neurology

Main topics addressed in their work include:

  • DNA Repair Mechanisms
  • Alzheimer's Disease Research and Treatments
  • RNA Research and Splicing
  • Epigenetics and DNA Methylation
  • Cholinesterase and Neurodegenerative Diseases
  • Pharmacological Effects and Toxicity Studies
  • RNA Regulation and Disease

Among recent papers associated with Nakabeppu are:

  • Oxidative Stress and Microglial Response in Retinitis Pigmentosa, 2020, International Journal of Molecular Sciences
  • MTH1 and OGG1 maintain a low level of 8-oxoguanine in Alzheimer's brain, and prevent the progression of Alzheimer's pathogenesis, 2021, Scientific Reports
  • PCBP1 and PCBP2 both bind heavily oxidized RNA but cause opposing outcomes, suppressing or increasing apoptosis under oxidative conditions, 2020, Journal of Biological Chemistry
  • Cisplatin-Mediated Upregulation of APE2 Binding to MYH9 Provokes Mitochondrial Fragmentation and Acute Kidney Injury, 2020, Cancer Research
  • A high-fat diet exacerbates the Alzheimer's disease pathology in the hippocampus of the AppNL−F/NL−F knock-in mouse model, 2021, Aging Cell

Frequent coauthors collaborating with Nakabeppu include:

  • Kunihiko Sakumi
  • Nona Abolhassani
  • Daisuke Tsuchimoto
  • Jinling Han
  • István Boldogh

Their publications regularly appear in these venues:

  • Oxidative Medicine and Cellular Longevity
  • Scientific Reports
  • Free Radical Research
  • Journal of Biological Chemistry
  • Neuroscience Research

Best Publications

  • DNA binding activities of three murine Jun proteins: stimulation by Fos.

    Yusaku Nakabeppu;Kevin Ryder;Daniel Nathans

  • Regulation and expression of the adaptive response to alkylating agents.

    Tomas Lindahl;Barbara Sedgwick;Mutsuo Sekiguchi;Yusaku Nakabeppu

  • Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes.

    R. J. Christy;V. W. Yang;J. M. Ntambi;D. E. Geiman

  • Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments

    Bruce T. Hope;Heather E. Nye;Max B. Kelz;David W. Self

  • Galectin-1 is essential in tumor angiogenesis and is a target for antiangiogenesis therapy

    Victor L. J. L. Thijssen;Ruben Postel;Ricardo J. M. G. E. Brandwijk;Ruud P. M. Dings

  • A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity

    Yusaku Nakabeppu;Daniel Nathans

  • Expression and Differential Intracellular Localization of Two Major Forms of Human 8-Oxoguanine DNA Glycosylase Encoded by Alternatively Spliced OGG1 mRNAs

    Kenichi Nishioka;Toshio Ohtsubo;Hisanobu Oda;Toshiyuki Fujiwara

  • Chronic Fos-Related Antigens: Stable Variants of ΔFosB Induced in Brain by Chronic Treatments

    Jingshan Chen;Max B. Kelz;Bruce T. Hope;Yusaku Nakabeppu

  • Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria

    Toshio Ohtsubo;Kenichi Nishioka;Yasuyuki Imaiso;Shigenori Iwai

  • Constitutive expression of zif268 in neocortex is regulated by synaptic activity.

    Paul F. Worley;Barbara A. Christy;Yusaku Nakabeppu;Ratan V. Bhat

  • JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a scaffold factor in the JNK signaling pathway

    Michihiko Ito;Katsuji Yoshioka;Mizuho Akechi;Shinya Yamashita

  • Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice

    Monica D. Bjørge;Gunn A. Hildrestrand;Katja Scheffler;Katja Scheffler;Rajikala Suganthan

  • Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase

    Teruhisa Tsuzuki;Akinori Egashira;Hisato Igarashi;Tomoo Iwakuma

  • Oxidative damage in nucleic acids and Parkinson's disease.

    Yusaku Nakabeppu;Daisuke Tsuchimoto;Hiroo Yamaguchi;Kunihiko Sakumi

  • Altered Expression of Diabetes-Related Genes in Alzheimer's Disease Brains: The Hisayama Study

    Masaaki Hokama;Sugako Oka;Julio Leon;Toshiharu Ninomiya

  • Mutagenesis and carcinogenesis caused by the oxidation of nucleic acids

    Yusaku Nakabeppu;Kunihiko Sakumi;Katsumi Sakamoto;Daisuke Tsuchimoto

  • The Oxidized Forms of dATP Are Substrates for the Human MutT Homologue, the hMTH1 Protein

    Katsuyoshi Fujikawa;Hiroyuki Kamiya;Hiroyuki Yakushiji;Yoshimitsu Fujii

  • Ogg1 Knockout-associated Lung Tumorigenesis and Its Suppression by Mth1 Gene Disruption

    Kunihiko Sakumi;Yohei Tominaga;Masato Furuichi;Ping Xu

  • Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs

    Sugako Oka;Mizuki Ohno;Daisuke Tsuchimoto;Kunihiko Sakumi

  • Hydrogen in Drinking Water Reduces Dopaminergic Neuronal Loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson's Disease

    Kyota Fujita;Toshihiro Seike;Noriko Yutsudo;Mizuki Ohno

Frequent Co-Authors

Kunihiko Sakumi
Kunihiko Sakumi Kyushu University
Mutsuo Sekiguchi
Mutsuo Sekiguchi Kyushu University
mutsuo sekiguchi
mutsuo sekiguchi Fukuoka Dental College
Yuriko Yamagata
Yuriko Yamagata Kumamoto University
Dongchon Kang
Dongchon Kang Kyushu University
Masahiro Shirakawa
Masahiro Shirakawa Kyoto University
Hiroyuki Kamiya
Hiroyuki Kamiya Hiroshima University
Yutaka Kiyohara
Yutaka Kiyohara Kyushu University
Shinya Toyokuni
Shinya Toyokuni Nagoya University
Mami Noda
Mami Noda Kyushu University

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