World's Best Scientists 2026 revealed!
Kunihiko Sakumi

Kunihiko Sakumi

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
8957
World Ranking
17647
National Ranking
1271

Kunihiko Sakumi publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Kunihiko Sakumi sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 123 publications — 13th percentile

13% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Kunihiko Sakumi D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Kunihiko Sakumi sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 50 D-Index — 11th percentile

11% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Kunihiko Sakumi is a researcher affiliated with Kyushu University in Japan. Their scientific work primarily spans the fields of Medicine and Neuroscience, with a particular focus on Alzheimer's disease research and related neurodegenerative disorders.

Sakumi's recent research outputs include the following publications:

  • MTH1 and OGG1 maintain a low level of 8-oxoguanine in Alzheimer's brain, and prevent the progression of Alzheimer's pathogenesis (2021, Scientific Reports)
  • A high-fat diet exacerbates the Alzheimer's disease pathology in the hippocampus of the AppNL−F/NL−F knock-in mouse model (2021, Aging Cell)
  • MUTYH Actively Contributes to Microglial Activation and Impaired Neurogenesis in the Pathogenesis of Alzheimer's Disease (2021, Oxidative Medicine and Cellular Longevity)
  • Environmental aircraft noise aggravates oxidative DNA damage, granulocyte oxidative burst and nitrate resistance in Ogg1-/- mice (2020, Free Radical Research)
  • Neural stem cell-specific ITPA deficiency causes neural depolarization and epilepsy (2020, JCI Insight)

Their research addresses several main topics, including:

  • Alzheimer's disease research and treatments
  • Cholinesterase and Neurodegenerative Diseases
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Pharmacological Effects and Toxicity Studies
  • Neuroscience and Neuropharmacology Research
  • Neurogenesis and neuroplasticity mechanisms
  • Noise Effects and Management

Sakumi's work is aligned with specific subfields such as Physiology, Neurology, Pharmacology, Pediatrics, Perinatology and Child Health, and Cellular and Molecular Neuroscience.

They have frequently published research in the following scientific venues:

  • Scientific Reports
  • Oxidative Medicine and Cellular Longevity
  • Free Radical Research
  • Aging Cell
  • JCI Insight

The researcher collaborates regularly with several coauthors including:

  • Yusaku Nakabeppu
  • Nona Abolhassani
  • Guianfranco Mazzei
  • Takashi Saito
  • Takaomi C. Saido

Best Publications

  • Targeted disruption of the Rad51 gene leads to lethality in embryonic mice.

    T Tsuzuki;Y Fujii;K Sakumi;Y Tominaga

  • Cloning and expression of cDNA for a human enzyme that hydrolyzes 8-oxo-dGTP, a mutagenic substrate for DNA synthesis.

    K. Sakumi;M. Furuichi;T. Tsuzuki;T. Kakuma

  • Oxidative damage in nucleic acids and Parkinson's disease.

    Yusaku Nakabeppu;Daisuke Tsuchimoto;Hiroo Yamaguchi;Kunihiko Sakumi

  • Mutagenesis and carcinogenesis caused by the oxidation of nucleic acids

    Yusaku Nakabeppu;Kunihiko Sakumi;Katsumi Sakamoto;Daisuke Tsuchimoto

  • Ogg1 Knockout-associated Lung Tumorigenesis and Its Suppression by Mth1 Gene Disruption

    Kunihiko Sakumi;Yohei Tominaga;Masato Furuichi;Ping Xu

  • Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs

    Sugako Oka;Mizuki Ohno;Daisuke Tsuchimoto;Kunihiko Sakumi

  • Hydrogen in Drinking Water Reduces Dopaminergic Neuronal Loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson's Disease

    Kyota Fujita;Toshihiro Seike;Noriko Yutsudo;Mizuki Ohno

  • Generation and Elimination of 8-Oxo-7,8-dihydro-2'-deoxyguanosine 5'-Triphosphate, a Mutagenic Substrate for DNA Synthesis, in Human Cells

    Hiroshi Hayakawa;Akinobu Taketomi;Kunihiko Sakumi;Michihiko Kuwano

  • Human APE2 protein is mostly localized in the nuclei and to some extent in the mitochondria, while nuclear APE2 is partly associated with proliferating cell nuclear antigen

    Daisuke Tsuchimoto;Yasunari Sakai;Kunihiko Sakumi;Kenichi Nishioka

  • Methylnitrosourea-induced Tumorigenesis in MGMT Gene Knockout Mice

    Kunihiko Sakumi;Akiko Shiraishi;Seiichiro Shimizu;Teruhisa Tsuzuki

  • SEPARATION OF KILLING AND TUMORIGENIC EFFECTS OF AN ALKYLATING AGENT IN MICE DEFECTIVE IN TWO OF THE DNA REPAIR GENES

    Hisaya Kawate;Kunihiko Sakumi;Teruhisa Tsuzuki;Yoko Nakatsuru

  • 8-oxoguanine causes spontaneous de novo germline mutations in mice

    Mizuki Ohno;Kunihiko Sakumi;Ryutaro Fukumura;Masato Furuichi

  • An oxidized purine nucleoside triphosphatase, MTH1 suppresses cell death caused by oxidative stress

    Daisuke Yoshimura;Kunihiko Sakumi;Mizuki Ohno;Yasunari Sakai

  • 8-Oxoguanine Formation Induced by Chronic UVB Exposure Makes Ogg1 Knockout Mice Susceptible to Skin Carcinogenesis

    Makoto Kunisada;Kunihiko Sakumi;Yohei Tominaga;Arief Budiyanto

  • MUTYH-null mice are susceptible to spontaneous and oxidative stress induced intestinal tumorigenesis.

    Katsumi Sakamoto;Yohei Tominaga;Kazumi Yamauchi;Kazumi Yamauchi;Yoshimichi Nakatsu

  • Structures and functions of DNA glycosylases.

    Kunihiko Sakumi;Mutsuo Sekiguchi

  • Comparative profiling of cortical gene expression in Alzheimer's disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation.

    Erika Castillo;Julio Leon;Julio Leon;Guianfranco Mazzei;Nona Abolhassani

  • 8-Oxoguanine DNA Glycosylase (OGG1) Deficiency Increases Susceptibility to Obesity and Metabolic Dysfunction

    Harini Sampath;Vladimir Vartanian;M. Rick Rollins;Kunihiko Sakumi

  • The defense mechanisms in mammalian cells against oxidative damage in nucleic acids and their involvement in the suppression of mutagenesis and cell death.

    Yusaku Nakabeppu;Daisuke Tsuchimoto;Masato Furuichi;Kunihiko Sakumi

  • 8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair

    Zijing Sheng;Sugako Oka;Daisuke Tsuchimoto;Nona Abolhassani

Frequent Co-Authors

Yusaku Nakabeppu
Yusaku Nakabeppu Kyushu University
Mutsuo Sekiguchi
Mutsuo Sekiguchi Kyushu University
mutsuo sekiguchi
mutsuo sekiguchi Fukuoka Dental College
Shinya Toyokuni
Shinya Toyokuni Nagoya University
Tetsuo Noda
Tetsuo Noda Japanese Foundation For Cancer Research
Frank M. LaFerla
Frank M. LaFerla University of California, Irvine
Takashi Saito
Takashi Saito Nagoya City University
Takaomi C. Saido
Takaomi C. Saido RIKEN Center for Brain Science
Yutaka Kiyohara
Yutaka Kiyohara Kyushu University
Mami Noda
Mami Noda Kyushu University

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