D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 62 Citations 11,053 176 World Ranking 1234 National Ranking 108

Overview

What is he best known for?

The fields of study Mutsuo Sekiguchi is best known for:

  • Gene
  • DNA
  • Enzyme

As part of his Transversion and Mutagenesis and Mutation studies, Mutsuo Sekiguchi is studying Mutation. Mutsuo Sekiguchi merges Gene with Transversion in his research. By researching both DNA and DNA damage, he produces research that crosses academic boundaries. Mutsuo Sekiguchi performs integrative study on DNA damage and DNA in his works. He integrates Molecular biology and Plasmid in his studies. His study on Biochemistry is mostly dedicated to connecting different topics, such as Mutagenesis. While working in this field, Mutsuo Sekiguchi studies both Genetics and Microbiology. In his works, Mutsuo Sekiguchi conducts interdisciplinary research on Microbiology and Genetics. With his scientific publications, his incorporates both Escherichia coli and Enzyme.

His most cited work include:

  • MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis (820 citations)
  • REGULATION AND EXPRESSION OF THE ADAPTIVE RESPONSE TO ALKYLATING AGENTS (628 citations)
  • Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase (267 citations)

What are the main themes of his work throughout his whole career to date

In his study, Mutsuo Sekiguchi carries out multidisciplinary Gene and Mutagenesis research. By researching both Molecular biology and Plasmid, he produces research that crosses academic boundaries. Mutsuo Sekiguchi performs multidisciplinary study in the fields of DNA and DNA damage via his papers. DNA damage and DNA are two areas of study in which he engages in interdisciplinary research. His work on DNA repair expands to the thematically related Biochemistry. His Genetics study frequently draws connections to adjacent fields such as DNA repair. He conducts interdisciplinary study in the fields of Escherichia coli and Enzyme through his works. He combines Enzyme and Escherichia coli in his research. He integrates Mutant and Genetics in his research.

Mutsuo Sekiguchi most often published in these fields:

  • Gene (88.04%)
  • Molecular biology (69.57%)
  • DNA (67.39%)

What were the highlights of his more recent work (between 2013-2020)?

  • Cell biology (81.82%)
  • Gene (72.73%)
  • Molecular biology (63.64%)

In recent works Mutsuo Sekiguchi was focusing on the following fields of study:

Mutsuo Sekiguchi brings together Cell biology and Molecular biology to produce work in his papers. Molecular biology and Cell biology are two areas of study in which Mutsuo Sekiguchi engages in interdisciplinary work. He integrates many fields, such as Gene and Computational biology, in his works. Mutsuo Sekiguchi merges Computational biology with Gene in his study. His Genome research extends to the thematically linked field of Biochemistry. His research on Genome frequently links to adjacent areas such as Biochemistry. His Genetics study frequently draws connections between related disciplines such as Blot. The study of Blot is intertwined with the study of Genetics in a number of ways. Mutsuo Sekiguchi integrates Apoptosis with Programmed cell death in his research.

Between 2013 and 2020, his most popular works were:

  • Transcriptional mutagenesis mediated by 8-oxoG induces translational errors in mammalian cells (48 citations)
  • Specific binding of PCBP1 to heavily oxidized RNA to induce cell death (39 citations)
  • Role of Auf1 in elimination of oxidatively damaged messenger RNA in human cells (28 citations)

In his most recent research, the most cited works focused on:

  • Gene
  • DNA
  • RNA

His study deals with a combination of Molecular biology and DNA. Mutsuo Sekiguchi integrates many fields in his works, including DNA and Genetics. His research on Genetics frequently connects to adjacent areas such as Messenger RNA. As part of his studies on Messenger RNA, Mutsuo Sekiguchi frequently links adjacent subjects like Biochemistry. By researching both Biochemistry and Cell biology, he produces research that crosses academic boundaries. He incorporates Cell biology and Gene in his research. In his works, he undertakes multidisciplinary study on Gene and Gene expression. His work blends Gene expression and Molecular biology studies together. He performs integrative RNA and RNA-binding protein research in his work.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Mutt protein specifically hydrolyses a potent mutagenic substrate for dna synthesis

Hisaji Maki;Mutsuo Sekiguchi.
Nature (1992)

1237 Citations

Cloning and expression of cDNA for a human enzyme that hydrolyzes 8-oxo-dGTP, a mutagenic substrate for DNA synthesis.

K. Sakumi;M. Furuichi;T. Tsuzuki;T. Kakuma.
Journal of Biological Chemistry (1993)

604 Citations

Hydrolytic elimination of a mutagenic nucleotide, 8-oxodGTP, by human 18-kilodalton protein: sanitization of nucleotide pool.

Jin-Yao Mo;Hisaji Maki;Mutsuo Sekiguchi.
Proceedings of the National Academy of Sciences of the United States of America (1992)

420 Citations

Transforming gene from human stomach cancers and a noncancerous portion of stomach mucosa.

Hiromi Sakamoto;Midori Mori;Masanori Taira;Teruhiko Yoshida.
Proceedings of the National Academy of Sciences of the United States of America (1986)

335 Citations

Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation.

M Ohtsubo;R Kai;N Furuno;T Sekiguchi.
Genes & Development (1987)

263 Citations

Ogg1 Knockout-associated Lung Tumorigenesis and Its Suppression by Mth1 Gene Disruption

Kunihiko Sakumi;Yohei Tominaga;Masato Furuichi;Ping Xu.
Cancer Research (2003)

256 Citations

Restoration of ultraviolet-induced unscheduled DNA synthesis of xeroderma pigmentosum cells by the concomitant treatment with bacteriophage T4 endonuclease V and HVJ (Sendai virus).

Kiyoji Tanaka;Mutsuo Sekiguchi;Yoshio Okada.
Proceedings of the National Academy of Sciences of the United States of America (1975)

256 Citations

MUTANTS OF ESCHERICHIA COLI PERMEABLE TO ACTINOMYCIN

Mutsuo Sekiguchi;Shoko Iida.
Proceedings of the National Academy of Sciences of the United States of America (1967)

237 Citations

T4 Endonuclease Involved in Repair of DNA

Seiichi Yasuda;Mutsuo Sekiguchi.
Proceedings of the National Academy of Sciences of the United States of America (1970)

220 Citations

Silencing effect of CpG island hypermethylation and histone modifications on O6-methylguanine-DNA methyltransferase (MGMT) gene expression in human cancer

Tetsuji Nakagawachi;Hidenobu Soejima;Takeshi Urano;Wei Zhao.
Oncogene (2003)

199 Citations

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