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Genetics

D-Index
66
Citations
13771
World Ranking
2634
National Ranking
1163

Overview

Susan S. Wallace is affiliated with the University of Vermont in the United States and works primarily within the field of Biochemistry, Genetics and Molecular Biology. Their contributions span several subfields, including Molecular Biology, Plant Science, Genetics, Public Health, Environmental and Occupational Health, and Immunology.

Their research covers a range of topics, predominantly focusing on DNA repair mechanisms. Other areas of study include plant genetic and mutation studies, CRISPR and genetic engineering, chronic lymphocytic leukemia research, acute lymphoblastic leukemia research, immunodeficiency and autoimmune disorders, as well as carcinogens and genotoxicity assessment.

Recent publications by Susan S. Wallace and collaborators include the following:

  • "Cooperation of the NEIL3 and Fanconi anemia/BRCA pathways in interstrand crosslink repair" (2020) published in Nucleic Acids Research
  • "Caught in motion: human NTHL1 undergoes interdomain rearrangement necessary for catalysis" (2021) published in Nucleic Acids Research
  • "Molecular radiobiology and the origins of the base excision repair pathway: an historical perspective" (2021) published in International Journal of Radiation Biology
  • "Consequences and repair of radiation-induced DNA damage: fifty years of fun questions and answers" (2021) published in International Journal of Radiation Biology
  • "The role of the PTHrP /Ihh feedback loop in the unusual growth plate location in mammalian metatarsals and pisiforms" (2025) published in Developmental Dynamics

Collaborations are an important aspect of their work, with frequent co-authors including Sylvie Doublé, Brittany L. Carroll, Karl E. Zahn, John Hanley, and Julie A. Dragon. These collaborative efforts have contributed to publications in several well-known scientific journals.

Key venues where Susan S. Wallace has frequently published include:

  • Nucleic Acids Research
  • International Journal of Radiation Biology
  • Developmental Dynamics
  • DNA Repair
  • bioRxiv (Cold Spring Harbor Laboratory)

Their research outputs emphasize mechanistic insights into DNA damage and repair processes, with an interdisciplinary approach that intersects molecular biology and genetics. This is reflected both in their choice of publication venues and the diversity of research topics addressed.

Best Publications

  • New substrates for old enzymes. 5-Hydroxy-2'-deoxycytidine and 5-hydroxy- 2'-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2'-deoxyuridine is a substrate for uracil DNA N-glycosylase

    Zafer Hatahet;Y. W. Kow;A. A. Purmal;R. P. Cunningham

  • A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIII

    Viswanath Bandaru;Sirisha Sunkara;Susan S Wallace;Jeffrey P Bond

  • Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro

    Hiroshi Ide;Yoke Wah Kow;Susan S. Wallace

  • Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli.

    Jeffrey O. Blaisdell;Susan S. Wallace

  • Characterization of the Escherichia coli X-ray endonuclease, endonuclease III.

    Harold L. Katcher;Susan S. Wallace

  • A novel, sensitive, and specific assay for abasic sites, the most commonly produced DNA lesion.

    Kihei Kubo;Hiroshi Ide;Susan S. Wallace;Yoke W. Kow

  • Attempted base excision repair of ionizing radiation damage in human lymphoblastoid cells produces lethal and mutagenic double strand breaks.

    Ning Yang;Heather Galick;Susan S. Wallace

  • Isolation and characterization of endonuclease VIII from Escherichia coli

    Robert J. Melamede;Zafer Hatahet;Yoke W. Kow;Hiroshi Ide

  • In vitro repair of synthetic ionizing radiation-induced multiply damaged DNA sites.

    Lynn Harrison;Zafer Hatahet;Susan S Wallace

  • Mechanism of action of Escherichia coli endonuclease III.

    Yoke W. Kow;Susan S. Wallace

  • Major oxidative products of cytosine, 5-hydroxycytosine and 5-hydroxyuracil, exhibit sequence context-dependent mispairing in vitro

    Andrei A. Purmal;Yoke Wah Kow;Susan S. Wallace

  • Escherichia coli endonuclease VIII: cloning, sequencing, and overexpression of the nei structural gene and characterization of nei and nei nth mutants.

    Dongyan Jiang;Zafer Hatahet;Jeffrey O. Blaisdell;Robert J. Melamede

  • Characterization of Escherichia coli Endonuclease VIII

    Dongyan Jiang;Zafer Hatahet;Robert J. Melamede;Yoke Wah Kow

  • The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo

    Minmin Liu;Viswanath Bandaru;Jeffrey P. Bond;Pawel Jaruga;Pawel Jaruga

  • Single-Stranded Breaks in DNA but Not Oxidative DNA Base Damages Block Transcriptional Elongation by RNA Polymerase II in HeLa Cell Nuclear Extracts

    Scott D. Kathe;Guang-Ping Shen;Susan S. Wallace

  • Crystallographic snapshots of a replicative DNA polymerase encountering an abasic site

    Matthew Hogg;Susan S Wallace;Sylvie Doublié

  • Base excision repair by hNTH1 and hOGG1: a two edged sword in the processing of DNA damage in gamma-irradiated human cells.

    Ning Yang;M. Ahmad Chaudhry;Susan S. Wallace

  • The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activity.

    Sylvie Doublié;Viswanath Bandaru;Jeffrey P. Bond;Susan S. Wallace

  • Multiply damaged sites in DNA: interactions with Escherichia coli endonucleases III and VIII.

    Lynn Harrison;Zafer Hatahet;Andrei A. Purmal;Susan S. Wallace

  • Human DNA polymerase κ bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides

    Paula L. Fischhaber;Valerie L. Gerlach;William J. Feaver;Zafer Hatahet

Frequent Co-Authors

Hiroshi Ide
Hiroshi Ide Hiroshima University
Cynthia J. Burrows
Cynthia J. Burrows University of Utah
Bernard F. Erlanger
Bernard F. Erlanger Columbia University
Jia Zhou
Jia Zhou The University of Texas Medical Branch at Galveston
Pawel Jaruga
Pawel Jaruga National Institute of Standards and Technology
Miral Dizdaroglu
Miral Dizdaroglu National Institute of Standards and Technology
David M. Warshaw
David M. Warshaw University of Vermont
Alan E. Tomkinson
Alan E. Tomkinson University of New Mexico
Nicholas H. Heintz
Nicholas H. Heintz University of Vermont
Yoshiharu Kimura
Yoshiharu Kimura Kyoto Institute of Technology

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