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Molecular Biology

D-Index
57
Citations
10049
World Ranking
2159
National Ranking
1073

Overview

Paul W. Doetsch is affiliated with the National Institute of Environmental Health Sciences in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a substantial body of work in molecular biology.

Their scientific contributions engage with several specialized subfields, including molecular medicine, ecology, pulmonary and respiratory medicine, and oncology.

Key topics that characterize their research efforts include:

  • DNA Repair Mechanisms
  • Antibiotic Resistance in Bacteria
  • Bacteriophages and microbial interactions
  • Bacterial biofilms and quorum sensing
  • Metabolomics and Mass Spectrometry Studies
  • Glutathione Transferases and Polymorphisms
  • Radiation Therapy and Dosimetry

They have published in various scientific venues, with frequent contributions to the following journals:

  • Journal of Biological Chemistry
  • Scientific Reports
  • Nucleic Acids Research
  • Encyclopedia of Life Sciences

Recent papers by Paul W. Doetsch include:

  • A role for the stringent response in ciprofloxacin resistance in Pseudomonas aeruginosa, 2024, Scientific Reports
  • Changes in metabolic landscapes shape divergent but distinct mutational signatures and cytotoxic consequences of redox stress, 2023, Nucleic Acids Research
  • Author Index, 2020, Journal of Biological Chemistry
  • Withdrawal: Distinct roles of Ape1 protein, an enzyme involved in DNA repair, in high or low linear energy transfer ionizing radiation-induced cell killing, 2020, Journal of Biological Chemistry
  • DNA Damage, 2020, Encyclopedia of Life Sciences

Among frequent coauthors, they have collaborated notably with Natalya Degtyareva, Victoria C. Placentra, Francis A. Cucinotta, William S. Dynan, and Libertad García-Villada.

Best Publications

  • Cisplatin induces a mitochondrial-ROS response that contributes to cytotoxicity depending on mitochondrial redox status and bioenergetic functions.

    Rossella Marullo;Erica Werner;Natalya Degtyareva;Bryn Moore

  • The enzymology of apurinic/apyrimidinic endonucleases

    Paul W. Doetsch;Richard P. Cunningham

  • DNA damage-induced reactive oxygen species (ROS) stress response in Saccharomyces cerevisiae.

    Lori A. Rowe;Natalya Degtyareva;Paul W. Doetsch

  • Base excision repair of oxidative DNA damage activated by XPG protein.

    Arne Klungland;Matthias Höss;Daniela Gunz;Angelos Constantinou

  • Overlapping specificities of base excision repair, nucleotide excision repair, recombination, and translesion synthesis pathways for DNA base damage in Saccharomyces cerevisiae.

    Rebecca L. Swanson;Natalie J. Morey;Paul W. Doetsch;Sue Jinks-Robertson

  • The current state of eukaryotic DNA base damage and repair.

    Nicholas C. Bauer;Anita H. Corbett;Paul W. Doetsch

  • Biological consequences of oxidative stress-induced DNA damage in Saccharomyces cerevisiae

    Tiffany B. Salmon;Barbara A. Evert;Binwei Song;Paul W. Doetsch

  • Effects of abasic sites and DNA single-strand breaks on prokaryotic RNA polymerases

    Wei Zhou;Paul W. Doetsch

  • RNA polymerase encounters with DNA damage: transcription-coupled repair or transcriptional mutagenesis?

    Tina T Saxowsky;Paul W Doetsch

  • MicroRNA-21 Modulates the Levels of Reactive Oxygen Species by Targeting SOD3 and TNFα

    Xiangming Zhang;Wooi Loon Ng;Ping Wang;Linlin Tian

  • Oxidative DNA damage causes mitochondrial genomic instability in Saccharomyces cerevisiae.

    Nicole A. Doudican;Binwei Song;Gerald S. Shadel;Paul W. Doetsch

  • Transcriptional Mutagenesis Induced by Uracil and 8-Oxoguanine in Escherichia coli

    Damien Brégeon;Zara A Doddridge;Ho Jin You;Bernard Weiss

  • SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination.

    Waaqo Daddacha;Allyson E. Koyen;Amanda J. Bastien;Pamela Sara E. Head

  • Mechanisms Regulating Protein Localization.

    Nicholas C. Bauer;Nicholas C. Bauer;Paul W. Doetsch;Anita H. Corbett

  • DNA binding properties of YB-1 and dbpA: binding to double-stranded, single-stranded, and abasic site containing DNAs.

    Susan L. Hasegawa;Paul W. Doetsch;Krista K. Hamilton;Amy M. Martin

  • Monomeric base damage products from adenine, guanine, and thymine induced by exposure of DNA to ultraviolet radiation.

    Paul W. Doetsch;Tomasz H. Zastawny;Amy M. Martin;Miral Dizdaroglu

  • A Drosophila ribosomal protein contains 8-oxoguanine and abasic site DNA repair activities.

    Adly Yacoub;Laura Augeri;Mark Kelley;Paul W. Doetsch

  • Saccharomyces cerevisiae Ntg1p and Ntg2p: broad specificity N-glycosylases for the repair of oxidative DNA damage in the nucleus and mitochondria.

    Ho Jin You;Rebecca L. Swanson;Cindy Harrington;Anita H. Corbett

  • Mitochondrial Dysfunction Due to Oxidative Mitochondrial DNA Damage Is Reduced through Cooperative Actions of Diverse Proteins

    Thomas W. O'Rourke;Nicole A. Doudican;Melinda D. Mackereth;Paul W. Doetsch

  • 8-Oxoguanine-mediated transcriptional mutagenesis causes Ras activation in mammalian cells.

    Tina T. Saxowsky;Kellen L. Meadows;Arne Klungland;Paul W. Doetsch

Frequent Co-Authors

Xingming Deng
Xingming Deng Emory University
Anita H. Corbett
Anita H. Corbett Emory University
Taofeek K. Owonikoko
Taofeek K. Owonikoko Emory University
Suresh S. Ramalingam
Suresh S. Ramalingam Emory University
Walter J. Curran
Walter J. Curran Emory University
Luigi G. Marzilli
Luigi G. Marzilli Louisiana State University
Balveen Kaur
Balveen Kaur Augusta University
Gerald S. Shadel
Gerald S. Shadel Salk Institute for Biological Studies
Miral Dizdaroglu
Miral Dizdaroglu National Institute of Standards and Technology
Sue Jinks-Robertson
Sue Jinks-Robertson Duke University

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