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Molecular Biology

D-Index
65
Citations
23308
World Ranking
1646
National Ranking
6

Overview

Arne Klungland is affiliated with Oslo University Hospital in Norway and has a research profile primarily focused on biochemistry, genetics, and molecular biology. Their research extends notably into subfields such as molecular biology, cancer research, oncology, physiology, and cell biology.

Their work addresses a range of main topics including RNA modifications and cancer, epigenetics and DNA methylation, RNA research and splicing, cancer-related molecular mechanisms research, cancer-related gene regulation, DNA repair mechanisms, and RNA and protein synthesis mechanisms.

Klungland's publication record includes several papers in prominent scientific journals. Selected recent papers include:

  • KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes, 2020, Nature Cell Biology
  • TRMT6/61A-dependent base methylation of tRNA-derived fragments regulates gene-silencing activity and the unfolded protein response in bladder cancer, 2022, Nature Communications
  • ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing, 2021, Nature Cell Biology
  • Single-cell m6A mapping in vivo using picoMeRIP-seq, 2023, Nature Biotechnology
  • OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation, 2020, Cell Reports

These publications have appeared in leading venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Cell Biology, Nature Communications, Nucleic Acids Research, and Proceedings of the National Academy of Sciences.

Klungland frequently collaborates with several researchers, including John Arne Dahl, Magnar Bjørås, Rune Ougland, Mads Lerdrup, and Ida Monshaugen. Their coauthorship patterns reflect multidisciplinary teamwork within molecular biology and cancer research fields.

Best Publications

  • ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

    Guanqun Zheng;John Arne Dahl;Yamei Niu;Peter Fedorcsak

  • ACCUMULATION OF PREMUTAGENIC DNA LESIONS IN MICE DEFECTIVE IN REMOVAL OF OXIDATIVE BASE DAMAGE

    Arne Klungland;Ian Rosewell;Stephan Hollenbach;Elisabeth Larsen

  • Second pathway for completion of human DNA base excision‐repair: reconstitution with purified proteins and requirement for DNase IV (FEN1)

    Arne Klungland;Tomas Lindahl

  • Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein.

    Y Kubota;R A Nash;A Klungland;P Schär

  • DNA repair in mammalian cells: Base excision repair: the long and short of it.

    A. B. Robertson;A. Klungland;T. Rognes;I. Leiros

  • Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks.

    Tomas Lindahl;Masahiko S. Satoh;Guy G. Poirier;Arne Klungland

  • A majority of m6A residues are in the last exons, allowing the potential for 3′ UTR regulation

    Shengdong Ke;Endalkachew A. Alemu;Claudia Mertens;Emily Conn Gantman

  • Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm

    Jiangbo Wei;Jiangbo Wei;Fange Liu;Fange Liu;Zhike Lu;Zhike Lu;Zhike Lu;Qili Fei;Qili Fei

  • Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition

    John Arne Dahl;Inkyung Jung;Håvard Aanes;Gareth D. Greggains

  • OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells

    Irina V. Kovtun;Yuan Liu;Magnar Bjoras;Arne Klungland

  • ALKBH1-Mediated tRNA Demethylation Regulates Translation.

    Fange Liu;Fange Liu;Wesley Clark;Guanzheng Luo;Guanzheng Luo;Xiaoyun Wang

  • ALKBH5-dependent m6A demethylation controls splicing and stability of long 3′-UTR mRNAs in male germ cells

    Chong Tang;Rachel Klukovich;Hongying Peng;Zhuqing Wang

  • Repair of 8-Oxodeoxyguanosine Lesions in Mitochondrial DNA Depends on the Oxoguanine DNA Glycosylase (OGG1) Gene and 8-Oxoguanine Accumulates in the Mitochondrial DNA of OGG1-defective Mice

    Nadja C. de Souza-Pinto;Lars Eide;Barbara A. Hogue;Tanja Thybo

  • Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase

    Teresa Roldán-Arjona;Ying-Fei Wei;Kenneth C. Carter;Arne Klungland

  • Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood–brain water uptake and confers barrier function on perivascular astrocyte endfeet

    Nadia Nabil Haj-Yasein;Gry Fluge Vindedal;Martine Eilert-Olsen;Georg Andreas Gundersen

  • Base excision repair of oxidative DNA damage activated by XPG protein.

    Arne Klungland;Matthias Höss;Daniela Gunz;Angelos Constantinou

  • Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice

    Monica D. Bjørge;Gunn A. Hildrestrand;Katja Scheffler;Katja Scheffler;Rajikala Suganthan

  • Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema

    Alexander S. Thrane;Phillip M. Rappold;Takumi Fujita;Arnulfo Torres

  • Ythdf2-mediated m6A mRNA clearance modulates neural development in mice

    Miaomiao Li;Miaomiao Li;Xu Zhao;Xu Zhao;Wei Wang;Hailing Shi;Hailing Shi

  • Mammalian ALKBH8 Possesses tRNA Methyltransferase Activity Required for the Biogenesis of Multiple Wobble Uridine Modifications Implicated in Translational Decoding

    Lene Songe-Møller;Erwin van den Born;Vibeke Leihne;Cathrine B. Vågbø

Frequent Co-Authors

Magnar Bjørås
Magnar Bjørås Norwegian University of Science and Technology
Chuan He
Chuan He University of Chicago
Erling Seeberg
Erling Seeberg University of Oslo
Hans E. Krokan
Hans E. Krokan Norwegian University of Science and Technology
Yun-Gui Yang
Yun-Gui Yang Chinese Academy of Sciences
Tomas Lindahl
Tomas Lindahl The Francis Crick Institute
Linda H. Bergersen
Linda H. Bergersen University of Oslo
Zhike Lu
Zhike Lu University of Chicago
Erlend A. Nagelhus
Erlend A. Nagelhus University of Oslo
Bernd Epe
Bernd Epe Johannes Gutenberg University of Mainz

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