World's Best Scientists 2026 revealed!
Peter C. Dedon

Peter C. Dedon

D-Index & Metrics

Molecular Biology

D-Index
80
Citations
20501
World Ranking
1010
National Ranking
533

Research.com Recognitions

  • 2011 - Fellow of the American Chemical Society

Overview

Peter C. Dedon is a researcher affiliated with MIT in the United States, with a primary focus in the field of Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Molecular Biology, Ecology, Epidemiology, Cancer Research, and Infectious Diseases.

The research topics covered by Dedon include:

  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • RNA Research and Splicing
  • Genomics and Phylogenetic Studies
  • Bacteriophages and microbial interactions
  • Peptidase Inhibition and Analysis
  • Advanced biosensing and bioanalysis techniques

Dedon has published extensively, with a notable presence in prominent journals. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Nature Communications
  • Biomolecules
  • Frontiers in Microbiology

Their recent scholarly articles encompass the following works:

  • "SspABCD-SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities," published in 2020 in Nature Microbiology
  • "Comparative tRNA sequencing and RNA mass spectrometry for surveying tRNA modifications," published in 2020 in Nature Chemical Biology
  • "Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification," published in 2020 in Nature Communications
  • "Quantitative mapping of the cellular small RNA landscape with AQRNA-seq," published in 2021 in Nature Biotechnology
  • "Nick-seq for single-nucleotide resolution genomic maps of DNA modifications and damage," published in 2020 in Nucleic Acids Research

Among Dedon's frequent collaborators are:

  • Thomas J. Begley
  • Valérie de Crécy-Lagard
  • Michael S. DeMott
  • Jingjing Sun
  • Guangxin Sun

Peter C. Dedon was awarded the title of Fellow of the American Chemical Society in 2011.

Best Publications

  • m6A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells

    Pedro J. Batista;Benoit Molinie;Jinkai Wang;Kun Qu

  • Reactive nitrogen species in the chemical biology of inflammation.

    Peter C. Dedon;Steven R. Tannenbaum

  • DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

    Lisiane B. Meira;James M. Bugni;Stephanie L. Green;Chung-Wei Lee

  • A Quantitative Systems Approach Reveals Dynamic Control of tRNA Modifications during Cellular Stress

    Clement T. Y. Chan;Madhu Dyavaiah;Michael S. DeMott;Koli Taghizadeh

  • Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins

    Clement T.Y. Chan;Yan Ling Joy Pang;Wenjun Deng;I. Ramesh Babu

  • N(6)-Methyladenosine RNA Modification Regulates Shoot Stem Cell Fate in Arabidopsis.

    Lisha Shen;Zhe Liang;Xiaofeng Gu;Ying Chen

  • m(6)A-LAIC-seq reveals the census and complexity of the m(6)A epitranscriptome.

    Benoit Molinie;Jinkai Wang;Kok Seong Lim;Roman Hillebrand

  • Characterization of the reactions of platinum antitumor agents with biologic and nonbiologic sulfur-containing nucleophiles

    Peter C. Dedon;Richard F. Borch

  • Reactive species and DNA damage in chronic inflammation: reconciling chemical mechanisms and biological fates.

    Pallavi Lonkar;Peter C. Dedon

  • Free-radical mechanisms involved in the formation of sequence-dependent bistranded DNA lesions by the antitumor antibiotics bleomycin, neocarzinostatin, and calicheamicin.

    Peter C. Dedon;Irving H. Goldberg

  • Phosphorothioation of DNA in bacteria by dnd genes

    Lianrong Wang;Shi Chen;Shi Chen;Tiegang Xu;Koli Taghizadeh

  • Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens

    J G Fox;Y Feng;E J Theve;A R Raczynski

  • Quantitative analysis of ribonucleoside modifications in tRNA by HPLC-coupled mass spectrometry

    Dan Su;Clement T Y Chan;Chen Gu;Kok Seong Lim

  • Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer

    Aswin Mangerich;Charles G. F. Knutson;Nicola Maria Anne Parry;Sureshkumar Muthupalani

  • Effect of Diethyldithiocarbamate on cis-Diamminedichloroplatinum(II)-induced Cytotoxicity, DNA Cross-Linking, and γ-Glutamyl Transpeptidase Inhibition

    Donald L. Bodenner;Peter C. Dedon;Peter C. Keng;Richard F. Borch

  • Indirect mutagenesis by oxidative DNA damage: Formation of the pyrimidopurinone adduct of deoxyguanosine by base propenal

    Peter C. Dedon;John P. Plastaras;Carol A. Rouzer;Lawrence J. Marnett

  • The Chemical Toxicology of 2-Deoxyribose Oxidation in DNA

    Peter C. Dedon

  • Human AlkB Homolog ABH8 Is a tRNA Methyltransferase Required for Wobble Uridine Modification and DNA Damage Survival

    Dragony Fu;Jennifer A. N. Brophy;Clement T. Y. Chan;Kyle A. Atmore

  • Selective protection against cis-diamminedichloroplatinum(II)-induced toxicity in kidney, gut, and bone marrow by diethyldithiocarbamate

    Donald L. Bodenner;Peter C. Dedon;Peter C. Keng;Janet C. Katz

  • A Quantitative Systems Approach Reveals Dynamic Control of tRNA Modifications during Cellular Stress

    Tsz Yan Clement Chan;Madhu Dyavaiah;Michael S. DeMott;Koli Taghizadeh

Frequent Co-Authors

Julien Lescar
Julien Lescar Nanyang Technological University
Artur Scherf
Artur Scherf Institut Pasteur
Nicholas E. Geacintov
Nicholas E. Geacintov New York University
Peter R. Preiser
Peter R. Preiser Nanyang Technological University
Zixin Deng
Zixin Deng Shanghai Jiao Tong University
Pei-Yong Shi
Pei-Yong Shi GlaxoSmithKline (United Kingdom)

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