D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 53 Citations 11,679 150 World Ranking 8583 National Ranking 641

Overview

What is he best known for?

The fields of study he is best known for:

  • DNA
  • Gene
  • Enzyme

RNA, Transfer RNA, Biochemistry, Genetics and Methylation are his primary areas of study. His RNA research integrates issues from RNA methylation, Computational biology and Nucleotide. His research integrates issues of Protein biosynthesis, Base pair, Stereochemistry and Enzyme in his study of Transfer RNA.

His Methylation research includes elements of RNA-binding protein, Drosophila Protein and DNA methylation. His work deals with themes such as TRNA methyltransferase activity and TRNA Methyltransferase, which intersect with DNA methylation. His research investigates the connection between TRNA methylation and topics such as Molecular biology that intersect with problems in Post-transcriptional modification.

His most cited work include:

  • MODOMICS: a database of RNA modification pathways—2013 update (740 citations)
  • MODOMICS: a database of RNA modification pathways. 2017 update. (610 citations)
  • RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage (409 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in RNA, Transfer RNA, Biochemistry, Methylation and Genetics. Mark Helm combines subjects such as Nucleotide, DNA, Molecular biology, Cell biology and Computational biology with his study of RNA. His Molecular biology research is multidisciplinary, incorporating elements of Transcription and Mitochondrial DNA.

The Computational biology study combines topics in areas such as Epitranscriptomics and 2'-O-methylation. Mark Helm works mostly in the field of Transfer RNA, limiting it down to topics relating to Ribosomal RNA and, in certain cases, Small nucleolar RNA, as a part of the same area of interest. His Methylation study integrates concerns from other disciplines, such as Translation and DNA methylation.

He most often published in these fields:

  • RNA (61.62%)
  • Transfer RNA (38.38%)
  • Biochemistry (34.34%)

What were the highlights of his more recent work (between 2018-2021)?

  • RNA (61.62%)
  • Transfer RNA (38.38%)
  • Cell biology (12.63%)

In recent papers he was focusing on the following fields of study:

Mark Helm spends much of his time researching RNA, Transfer RNA, Cell biology, Computational biology and Nucleotide. RNA is a primary field of his research addressed under Biochemistry. His Transfer RNA research is multidisciplinary, relying on both 2'-O-methylation, Methylation and Enzyme.

His Cell biology research is multidisciplinary, incorporating elements of Gene expression, DNA methylation, TLR7, Innate immune system and Binding site. The Computational biology study combines topics in areas such as Reference genome, Deep sequencing, Epitranscriptomics, Microscale thermophoresis and Sequence analysis. Mark Helm combines subjects such as Molecular biology, Manganese and DNA polymerase with his study of Nucleotide.

Between 2018 and 2021, his most popular works were:

  • A tRNA half modulates translation as stress response in Trypanosoma brucei (47 citations)
  • Methods for RNA Modification Mapping Using Deep Sequencing: Established and New Emerging Technologies. (43 citations)
  • RNA Modifications Modulate Activation of Innate Toll-Like Receptors. (25 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

Mark Helm mainly focuses on RNA, Transfer RNA, Cell biology, Enzyme and Computational biology. His study of Uridine is a part of RNA. His study in Transfer RNA is interdisciplinary in nature, drawing from both Complementary DNA, Non-coding RNA, Polymerase and Methylation.

His Cell biology research includes themes of Transcriptome, TLR7, Innate immune system and DNA methylation. His Enzyme research entails a greater understanding of Biochemistry. Mark Helm has included themes like Microscale thermophoresis, Ribosomal RNA, RNA modification and Tissue Differentiation in his Computational biology study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

MODOMICS: a database of RNA modification pathways—2013 update

Magdalena A. Machnicka;Kaja Milanowska;Okan Osman Oglou;Elzbieta Purta.
Nucleic Acids Research (2012)

890 Citations

MODOMICS: a database of RNA modification pathways. 2017 update.

Pietro Boccaletto;Magdalena A Machnicka;Magdalena A Machnicka;Elzbieta Purta;Pawel Piatkowski.
Nucleic Acids Research (2018)

708 Citations

RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage

Matthias Schaefer;Tim Pollex;Katharina Hanna;Francesca Tuorto.
Genes & Development (2010)

507 Citations

Post-transcriptional nucleotide modification and alternative folding of RNA.

Mark Helm.
Nucleic Acids Research (2006)

444 Citations

tRNA stabilization by modified nucleotides.

Yuri Motorin;Mark Helm.
Biochemistry (2010)

385 Citations

RNA nucleotide methylation

Yuri Motorin;Mark Helm.
Wiley Interdisciplinary Reviews - Rna (2011)

355 Citations

Search for characteristic structural features of mammalian mitochondrial tRNAs.

Mark Helm;Hervé Brulé;Dagmar Friede;Richard Giegé.
RNA (2000)

355 Citations

RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis.

Francesca Tuorto;Reinhard Liebers;Tanja Musch;Matthias Schaefer.
Nature Structural & Molecular Biology (2012)

341 Citations

Aberrant methylation of tRNAs links cellular stress to neuro‐developmental disorders

Sandra Blanco;Sabine Dietmann;Joana V Flores;Shobbir Hussain.
The EMBO Journal (2014)

306 Citations

Detecting RNA modifications in the epitranscriptome: predict and validate

Mark Helm;Yuri Motorin.
Nature Reviews Genetics (2017)

300 Citations

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