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Molecular Biology

D-Index
66
Citations
48071
World Ranking
1593
National Ranking
804

Overview

Qing Dai is affiliated with the University of Chicago in the United States, contributing extensively to the fields of biochemistry, genetics, and molecular biology. Their research primarily focuses on molecular biology, with significant work related to cancer research, cardiology and cardiovascular medicine, surgery, and oncology.

The scientist's main topics of investigation revolve around RNA modifications and cancer, cancer-related molecular mechanisms, RNA research and splicing, RNA and protein synthesis mechanisms, cancer-related gene regulation, epigenetics and DNA methylation, and DNA and nucleic acid chemistry.

Qing Dai has published research in several notable venues, with recurring contributions in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Biotechnology
  • Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
  • Nucleic Acids Research
  • Nature Protocols

Their recent publications include:

  • "Decoding the epitranscriptional landscape from native RNA sequences," 2020, Nucleic Acids Research
  • "N6-methyladenosine dynamics in neurodevelopment and aging, and its potential role in Alzheimer's disease," 2021, Genome Biology
  • "m6A RNA modifications are measured at single-base resolution across the mammalian transcriptome," 2022, Nature Biotechnology
  • "Quantitative sequencing using BID-seq uncovers abundant pseudouridines in mammalian mRNA at base resolution," 2022, Nature Biotechnology
  • "A metabolic labeling method detects m6A transcriptome-wide at single base resolution," 2020, Nature Chemical Biology

Qing Dai frequently collaborates with a network of co-authors, with the most common including:

  • Chuan He
  • Lisheng Zhang
  • Chang Ye
  • Kinga Pajdzik
  • Xiaoyang Dou

The scientist has authored over one hundred publications in the molecular biology subfield, contributing to a total of 135 publications in the broader discipline of biochemistry, genetics, and molecular biology. Their work intersects medicine, where they have contributed to 38 publications, focusing on areas such as cancer and cardiovascular medicine.

Best Publications

  • N6-methyladenosine-dependent regulation of messenger RNA stability

    Xiao Wang;Zhike Lu;Adrian Gomez;Gary C. Hon

  • Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

    Shinsuke Ito;Li Shen;Qing Dai;Susan C. Wu

  • N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO.

    Guifang Jia;Ye Fu;Xu Zhao;Xu Zhao;Qing Dai

  • A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

    Jianzhao Liu;Yanan Yue;Dali Han;Xiao Wang

  • ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

    Guanqun Zheng;John Arne Dahl;Yamei Niu;Peter Fedorcsak

  • Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA

    Yu-Fei He;Bin-Zhong Li;Zheng Li;Peng Liu

  • N 6 -methyladenosine-dependent RNA structural switches regulate RNA–protein interactions

    Nian Liu;Qing Dai;Guanqun Zheng;Chuan He

  • Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.

    Kelly Moran-Crusio;Linsey Reavie;Alan Shih;Omar Abdel-Wahab

  • Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine

    Chun Xiao Song;Keith E. Szulwach;Ye Fu;Qing Dai

  • Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome

    Miao Yu;Gary C. Hon;Keith E. Szulwach;Chun Xiao Song

  • R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling

    Rui Su;Lei Dong;Chenying Li;Sigrid Nachtergaele

  • The dynamic N 1 -methyladenosine methylome in eukaryotic messenger RNA

    Dan Dominissini;Dan Dominissini;Sigrid Nachtergaele;Sigrid Nachtergaele;Sharon Moshitch-Moshkovitz;Eyal Peer;Eyal Peer

  • 5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging

    Keith E. Szulwach;Xuekun Li;Yujing Li;Chun Xiao Song

  • Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis.

    Phillip J Hsu;Yunfei Zhu;Honghui Ma;Honghui Ma;Yueshuai Guo

  • N6-methyladenosine alters RNA structure to regulate binding of a low-complexity protein.

    Nian Liu;Katherine I. Zhou;Marc Parisien;Qing Dai

  • Genome-wide Profiling of 5-Formylcytosine Reveals Its Roles in Epigenetic Priming

    Chun-Xiao Song;Keith E. Szulwach;Qing Dai;Ye Fu

  • Efficient and quantitative high-throughput tRNA sequencing

    Guanqun Zheng;Yidan Qin;Wesley C Clark;Qing Dai

  • Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA

    Nian Liu;Marc Parisien;Qing Dai;Guanqun Zheng

  • ALKBH1-Mediated tRNA Demethylation Regulates Translation.

    Fange Liu;Fange Liu;Wesley Clark;Guanzheng Luo;Guanzheng Luo;Xiaoyun Wang

  • Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth.

    Taro Hitosugi;Lu Zhou;Shannon Elf;Jun Fan

Frequent Co-Authors

Chuan He
Chuan He University of Chicago
Tao Pan
Tao Pan Jinan University
Joseph A. Piccirilli
Joseph A. Piccirilli University of Chicago
Zhike Lu
Zhike Lu University of Chicago
Peng Jin
Peng Jin Emory University
Ronald G. Harvey
Ronald G. Harvey University of Chicago
Chengqi Yi
Chengqi Yi Peking University
Shutsung Liao
Shutsung Liao University of Chicago
Ninette Amariglio
Ninette Amariglio Sheba Medical Center
Gideon Rechavi
Gideon Rechavi Sheba Medical Center

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