World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
7640
World Ranking
18100
National Ranking
1243

Overview

Iris Bruchhaus is affiliated with the Bernhard Nocht Institute for Tropical Medicine in Germany. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with specific focus on subfields such as Public Health, Environmental and Occupational Health, Molecular Biology, Infectious Diseases, Immunology, and Parasitology.

The main topics of their work include Malaria Research and Control, Mosquito-borne diseases and control, Amoebic Infections and Treatments, Genetics, Aging, and Longevity in Model Organisms, Neurobiology and Insect Physiology Research, Parasitic Infections and Diagnostics, and Invertebrate Immune Response Mechanisms.

Bruchhaus has contributed to a number of research articles published in notable venues. Frequent publication outlets for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Microorganisms
  • eLife
  • PLoS Pathogens
  • iScience

Co-authorship has featured collaboration with several researchers, including:

  • Thomas Roeder
  • Nahla Galal Metwally
  • Johannes Allweier
  • Barbara Honecker
  • Katharina Höhn

Their recent publications cover a range of topics related to immunopathology, malaria, amoebiasis, and host-pathogen interactions. Notable papers include:

  • "Androgens predispose males to monocyte-mediated immunopathology by inducing the expression of leukocyte recruitment factor CXCL1," 2020, Nature Communications
  • "Common virulence gene expression in adult first-time infected malaria patients and severe cases," 2021, eLife
  • "HIF-1α modulates sex-specific Th17/Treg responses during hepatic amoebiasis," 2021, Journal of Hepatology
  • "CD36-A Host Receptor Necessary for Malaria Parasites to Establish and Maintain Infection," 2022, Microorganisms
  • "Adhesion between P. falciparum infected erythrocytes and human endothelial receptors follows alternative binding dynamics under flow and febrile conditions," 2020, Scientific Reports

Best Publications

  • The genome of the protist parasite Entamoeba histolytica

    Brendan Loftus;Iain Anderson;Rob Davies;U. Cecilia M. Alsmark

  • Metronidazole Resistance in the Protozoan Parasite Entamoeba histolytica Is Associated with Increased Expression of Iron-containing Superoxide Dismutase and Peroxiredoxin and Decreased Expression of Ferredoxin 1 and Flavin Reductase *

    Claudia Wassmann;Andrea Hellberg;Egbert Tannich;Iris Bruchhaus

  • The Intestinal Protozoan Parasite Entamoeba histolytica Contains 20 Cysteine Protease Genes, of Which Only a Small Subset Is Expressed during In Vitro Cultivation

    Iris Bruchhaus;Brendan J. Loftus;Neil Hall;Egbert Tannich

  • Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo.

    Subhash Ghosh;Julian M.W. Chan;Christopher R. Lea;Gary A. Meints

  • ENTAMOEBA HISTOLYTICA AND ENTAMOEBA DISPAR: DIFFERENCES IN NUMBERS AND EXPRESSION OF CYSTEINE PROTEINASE GENES

    Iris Bruchhaus;Thomas Jacobs;Matthias Leippe;Egbert Tannich

  • Structure and content of the Entamoeba histolytica genome.

    Clark Cg;Alsmark Uc;Tazreiter M;Saito-Nakano Y

  • Developmentally induced changes of the proteome in the protozoan parasite Leishmania donovani.

    Meike Bente;Simone Harder;Martina Wiesgigl;Jochen Heukeshoven

  • Unusual gene organization in the protozoan parasite Entamoeba histolytica.

    I. Bruchhaus;M. Leippe;C. Lioutas;E. Tannich

  • New phylogenomic data support the monophyly of Lophophorata and an Ectoproct-Phoronid clade and indicate that Polyzoa and Kryptrochozoa are caused by systematic bias.

    Maximilian P Nesnidal;Martin Helmkampf;Martin Helmkampf;Achim Meyer;Alexander Witek

  • Isolation and molecular characterization of a surface‐bound proteinase of Entamoeba histolytica

    Thomas Jacobs;Iris Bruchhaus;Thomas Dandekar;Egbert Tannich

  • Protozoan parasites: programmed cell death as a mechanism of parasitism.

    Iris Bruchhaus;Thomas Roeder;Annika Rennenberg;Volker T. Heussler

  • Absence of Erythrocyte Sequestration and Lack of Multicopy Gene Family Expression in Plasmodium falciparum from a Splenectomized Malaria Patient

    Anna Bachmann;Claudia Esser;Michaela Petter;Sabine Predehl

  • Overexpression of cysteine proteinase 2 in Entamoeba histolytica or Entamoeba dispar increases amoeba-induced monolayer destruction in vitro but does not augment amoebic liver abscess formation in gerbils

    A. Hellberg;R. Nickel;H. Lotter;E. Tannich

  • Phylogenomic analyses of lophophorates (brachiopods, phoronids and bryozoans) confirm the Lophotrochozoa concept

    Martin Helmkampf;Iris Bruchhaus;Bernhard Hausdorf

  • Spiralian Phylogenomics Supports the Resurrection of Bryozoa Comprising Ectoprocta and Entoprocta

    Bernhard Hausdorf;Martin Helmkampf;Achim Meyer;Alexander Witek

  • The Entamoeba histolytica genome: primary structure and expression of proteolytic enzymes

    Manuela Tillack;Laura Biller;Henriette Irmer;Michelle Freitas

  • A simple and reliable 5′-RACE approach

    Guido Schramm;Iris Bruchhaus;Thomas Roeder

  • Purification and molecular characterization of the NAD(+)-dependent acetaldehyde/alcohol dehydrogenase from Entamoeba histolytica.

    I Bruchhaus;E Tannich

  • Removal of hydrogen peroxide by the 29 kDa protein of Entamoeba histolytica

    Iris Bruchhaus;Symi Richter;Egbert Tannich

  • Caenopores are antimicrobial peptides in the nematode Caenorhabditis elegans instrumental in nutrition and immunity.

    Thomas Roeder;Mareike Stanisak;Christoph Gelhaus;Iris Bruchhaus

Frequent Co-Authors

Egbert Tannich
Egbert Tannich Bernhard Nocht Institute for Tropical Medicine
Bernhard Hausdorf
Bernhard Hausdorf Universität Hamburg
Matthias Leippe
Matthias Leippe Kiel University
Thorsten Burmester
Thorsten Burmester Universität Hamburg
Neil Hall
Neil Hall Norwich Research Park
Thomas D. Otto
Thomas D. Otto University of Glasgow
Thomas Lavstsen
Thomas Lavstsen University of Copenhagen
Tomoyoshi Nozaki
Tomoyoshi Nozaki University of Tokyo
Jonas Schmidt-Chanasit
Jonas Schmidt-Chanasit Universität Hamburg
Brendan J. Loftus
Brendan J. Loftus University College Dublin

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