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Biology and Biochemistry

D-Index
47
Citations
8598
World Ranking
18681
National Ranking
29

Overview

Jan Tachezy is affiliated with Charles University in the Czech Republic. Their research focuses primarily on biochemistry, genetics, and molecular biology, with significant contributions to immunology and microbiology. The subfields of study central to their work include molecular biology, parasitology, infectious diseases, microbiology, and insect science.

The scientist's research topics feature parasitic infections and diagnostics, protist diversity and phylogeny, genomics and phylogenetic studies, amoebic infections and treatments, reproductive tract infections research, RNA modifications and cancer, and reproductive system and pregnancy.

Recent publications by Jan Tachezy cover diverse aspects of molecular biology and microbiology. Notable papers include:

  • "Double-Stranded RNA Viruses Are Released From Trichomonas vaginalis Inside Small Extracellular Vesicles and Modulate the Exosomal Cargo," 2022, published in Frontiers in Microbiology
  • "The hydrogenosome of Trichomonas vaginalis," 2022, published in Journal of Eukaryotic Microbiology
  • "The Mastigamoeba balamuthi Genome and the Nature of the Free-Living Ancestor of Entamoeba," 2021, published in Molecular Biology and Evolution
  • "Anaerobic peroxisomes in Mastigamoeba balamuthi," 2020, published in Proceedings of the National Academy of Sciences
  • "Anaerobic derivates of mitochondria and peroxisomes in the free-living amoeba Pelomyxa schiedti revealed by single-cell genomics," 2022, published in BMC Biology

Jan Tachezy frequently collaborates with several researchers, with the most frequent co-authors being:

  • Ivan Hrdý
  • Vojtěch Žárský
  • Petr Rada
  • Ravi Kumar Narayanasamy
  • Tamara Smutná

The scientist's work is published predominantly in journals such as BMC Biology, Current Biology, Proceedings of the National Academy of Sciences, bioRxiv (Cold Spring Harbor Laboratory), and Frontiers in Microbiology.

Best Publications

  • Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis

    Jane M. Carlton;Robert . Hirt;Joana C. Silva;Arthur L. Delcher

  • Mitochondrial remnant organelles of Giardia function in iron-sulphur protein maturation

    Jorge Tovar;Gloria León-Avila;Lidya B Sánchez;Lidya B Sánchez;Robert Sutak

  • Evolution of the molecular machines for protein import into mitochondria.

    Pavel Dolezal;Vladimir A Likic;Jan Tachezy;Trevor James Lithgow

  • Trichomonas hydrogenosomes contain the NADH dehydrogenase module of mitochondrial complex I

    Ivan Hrdy;Robert P. Hirt;Pavel Dolezal;Lucie Bardonová

  • Mitochondrial Type Iron-Sulfur Cluster Assembly in the Amitochondriate Eukaryotes Trichomonas vaginalis and Giardia intestinalis, as Indicated by the Phylogeny of IscS

    Jan Tachezy;Lidya B. Sánchez;Miklós Müller

  • Giardia mitosomes and trichomonad hydrogenosomes share a common mode of protein targeting

    Pavel Dolezal;Ondrej Smid;Petr Rada;Zuzana Zubacova

  • Crusade for iron: iron uptake in unicellular eukaryotes and its significance for virulence

    Robert Sutak;Emmanuel Lesuisse;Jan Tachezy;Des R. Richardson

  • Mitochondrial-type assembly of FeS centers in the hydrogenosomes of the amitochondriate eukaryote Trichomonas vaginalis

    Robert Sutak;Pavel Dolezal;Heather L. Fiumera;Ivan Hrdy

  • The Minimal Proteome in the Reduced Mitochondrion of the Parasitic Protist Giardia intestinalis

    Petr L. Jedelský;Pavel Doležal;Petr Rada;Jan Pyrih

  • Cattle Pathogen Tritrichomonas foetus (Riedmüller, 1928) and Pig Commensal Tritrichomonas suis (Gruby & Delafond, 1843) Belong to the Same Species

    Jan Tachezy;Ruth Tachezy;Vladimír Hampl;Miroslava Šedinová

  • Mitochondrial-type iron–sulfur cluster biosynthesis genes (IscS and IscU) in the apicomplexan Cryptosporidium parvum

    Michael J. LaGier;Jan Tachezy;Frantisek Stejskal;Katerina Kutisova

  • Mechanisms of in vitro development of resistance to metronidazole in Trichomonas vaginalis.

    Dominique Rasoloson;Stepanka Vanacova;Eva Tomkova;Jakub Razga

  • Trichomonas vaginalis vast BspA-like gene family: evidence for functional diversity from structural organisation and transcriptomics

    Christophe J Noël;Nicia Diaz;Thomas Sicheritz-Ponten;Lucie Safarikova

  • Cryptic species within the Tetratrichomonas gallinarum species complex revealed by molecular polymorphism.

    Ivan Cepicka;Kateřina Kutišová;Jan Tachezy;Jaroslav Kulda

  • Molecular biology of the amitochondriate parasites, Giardia intestinalis, Entamoeba histolytica and Trichomonas vaginalis.

    Stepanka Vanacova;David R Liston;Jan Tachezy;Patricia J Johnson

  • In Vitro Induced Anaerobic Resistance to Metronidazole In Trichomonas Vaginalis

    Jaroslav Kulda;Jan Tachezy;Apolena Ĉerkasovova

  • Trichomonas vaginalis surface proteins: a view from the genome.

    Hirt Rp;Noel Cj;Sicheritz-Ponten T;Tachezy J

  • Deep sequencing of Trichomonas vaginalis during the early infection of vaginal epithelial cells and amoeboid transition.

    Sven B. Gould;Christian Woehle;Gary Kusdian;Giddy Landan

  • Knock-downs of iron-sulfur cluster assembly proteins IscS and IscU down-regulate the active mitochondrion of procyclic Trypanosoma brucei.

    Ondrej Smíd;Eva Horáková;Vanda Vilímová;Ivan Hrdý

  • The Core Components of Organelle Biogenesis and Membrane Transport in the Hydrogenosomes of Trichomonas vaginalis

    Petr Rada;Pavel Doležal;Petr L. Jedelský;Dejan Bursac

Frequent Co-Authors

Julius Lukeš
Julius Lukeš Czech Academy of Sciences
Trevor Lithgow
Trevor Lithgow Monash University
Joel B. Dacks
Joel B. Dacks University of Alberta
Miklós Müller
Miklós Müller Rockefeller University
Robert P. Hirt
Robert P. Hirt Newcastle University
T. Martin Embley
T. Martin Embley Newcastle University
Andrew Dancis
Andrew Dancis University of Pennsylvania
Patricia J. Johnson
Patricia J. Johnson University of California, Los Angeles
Andrew J. Roger
Andrew J. Roger Dalhousie University
Richard Cammack
Richard Cammack King's College London

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