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Biology and Biochemistry

D-Index
83
Citations
19232
World Ranking
3585
National Ranking
272

Overview

Thomas Becker is affiliated with Ludwig-Maximilians-Universität München in Germany. Their research primarily focuses on biochemistry, genetics, and molecular biology with a specialization in molecular biology as well as related subfields such as clinical biochemistry, cell biology, surgery, and cellular and molecular neuroscience.

The scientist's main topics of work include mitochondrial function and pathology, ATP synthase and ATPases research, metabolism and genetic disorders, ubiquitin and proteasome pathways, RNA and protein synthesis mechanisms, RNA modifications and cancer, and endoplasmic reticulum stress and disease.

Significant recent publications by Thomas Becker include the following papers:

  • "Quality control of the mitochondrial proteome," 2020, Nature Reviews Molecular Cell Biology
  • "Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion," 2020, Cell Metabolism
  • "Mitochondrial complexome reveals quality-control pathways of protein import," 2023, Nature
  • "Mitochondrial sorting and assembly machinery operates by β-barrel switching," 2021, Nature
  • "Mitochondria shed their outer membrane in response to infection-induced stress," 2022, Science

Frequent coauthors in their work include Fabian den Brave, Nikolaus Pfanner, Jiyao Song, Nils Wiedemann, and Uwe Schulte. These collaborations reflect a network centered on mitochondrial biology and related research areas.

Thomas Becker's publications have appeared in several notable venues, with the highest number of contributions in Cell Reports. Other frequently used publication venues include Nature, bioRxiv (Cold Spring Harbor Laboratory), Nature Structural & Molecular Biology, and Nature Metabolism.

Best Publications

  • Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.

    Matthias Thoms;Robert Buschauer;Michael Ameismeier;Lennart Koepke

  • Photosystem II core phosphorylation and photosynthetic acclimation require two different protein kinases

    Vera Bonardi;Vera Bonardi;Paolo Pesaresi;Thomas Becker;Enrico Schleiff

  • Structure of the signal recognition particle interacting with the elongation-arrested ribosome

    Mario Halic;Thomas Becker;Martin R. Pool;Christian M. T. Spahn

  • FOXO-dependent regulation of innate immune homeostasis

    Thomas Becker;Gerrit Loch;Marc Beyer;Ingo Zinke

  • Dual Role of Mitofilin in Mitochondrial Membrane Organization and Protein Biogenesis

    Karina von der Malsburg;Judith M. Müller;Maria Bohnert;Silke Oeljeklaus

  • Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome

    Thomas Becker;Shashi Bhushan;Alexander Jarasch;Jean Paul Armache

  • Cryo-EM structure of the ribosome–SecYE complex in the membrane environment

    Jens Frauenfeld;James Gumbart;Eli O van der Sluis;Eli O van der Sluis;Soledad Funes

  • Dissecting Membrane Insertion of Mitochondrial β-Barrel Proteins

    Stephan Kutik;Diana Stojanovski;Lars Becker;Thomas Becker

  • Quality control of the mitochondrial proteome.

    Jiyao Song;Johannes M. Herrmann;Thomas Becker

  • Structural insight into nascent polypeptide chain-mediated translational stalling.

    Birgit Seidelt;C. Axel Innis;Daniel N. Wilson;Marco Gartmann

  • Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways.

    Ken Ikeuchi;Petr Tesina;Yoshitaka Matsuo;Takato Sugiyama

  • Ubiquitination of stalled ribosome triggers ribosome-associated quality control

    Yoshitaka Matsuo;Ken Ikeuchi;Yasushi Saeki;Shintaro Iwasaki

  • Common ground for protein translocation: access control for mitochondria and chloroplasts

    Enrico Schleiff;Thomas Becker

  • Mitochondrial Cardiolipin Involved in Outer-Membrane Protein Biogenesis: Implications for Barth Syndrome

    Natalia Gebert;Amit S. Joshi;Stephan Kutik;Thomas Becker

  • Structural basis of highly conserved ribosome recycling in eukaryotes and archaea

    Thomas Becker;Sibylle Franckenberg;Stephan Wickles;Christopher J. Shoemaker

  • Phosphatidylethanolamine and Cardiolipin Differentially Affect the Stability of Mitochondrial Respiratory Chain Supercomplexes

    Lena Böttinger;Susanne E. Horvath;Thomas Kleinschroth;Carola Hunte

  • Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.

    Jean Paul Armache;Alexander Jarasch;Andreas M. Anger;Elizabeth Villa

  • Mitochondrial protein translocation-associated degradation.

    Christoph U Mårtensson;Chantal Priesnitz;Jiyao Song;Lars Ellenrieder

  • Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging

    York Kamenisch;Maria Fousteri;Jennifer Knoch;Anna-Katharina von Thaler

  • The Ccr4-Not complex monitors the translating ribosome for codon optimality.

    Robert Buschauer;Yoshitaka Matsuo;Takato Sugiyama;Ying Hsin Chen

Frequent Co-Authors

Nikolaus Pfanner
Nikolaus Pfanner University of Freiburg
Nils Wiedemann
Nils Wiedemann University of Freiburg
Roland Beckmann
Roland Beckmann Ludwig-Maximilians-Universität München
Enrico Schleiff
Enrico Schleiff Goethe University Frankfurt
Otto Berninghausen
Otto Berninghausen Ludwig-Maximilians-Universität München
Chris Meisinger
Chris Meisinger University of Freiburg
Bettina Warscheid
Bettina Warscheid University of Freiburg
Bernard Guiard
Bernard Guiard Centre national de la recherche scientifique, CNRS
Martin van der Laan
Martin van der Laan Saarland University
Agnieszka Chacinska
Agnieszka Chacinska IMol Polish Academy of Sciences

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