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Biology and Biochemistry

D-Index
62
Citations
14577
World Ranking
10738
National Ranking
773

Overview

Nils Wiedemann is a researcher affiliated with the University of Freiburg in Germany, specializing in biochemistry, genetics, and molecular biology. Their work spans a broad range of subfields, including molecular biology, clinical biochemistry, law, cell biology, and political science and international relations.

Their research focuses on several main topics, notably mitochondrial function and pathology, ATP synthase and ATPases research, RNA and protein synthesis mechanisms, metabolism and genetic disorders, digitalization, law, and regulation, fungal and yeast genetics research, as well as privacy, security, and data protection.

Wiedemann has contributed to multiple publications across prominent scientific venues. Frequent publication venues include:

  • Nature
  • Nature Reviews Molecular Cell Biology
  • Methods in Enzymology on CD-ROM/Methods in Enzymology
  • Nature Structural & Molecular Biology
  • Jusletter IT

Their recent papers highlight expertise in mitochondrial biology and protein transport mechanisms. Key recent publications include:

  • Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context (2021, Cell Metabolism)
  • Mitochondrial complexome reveals quality-control pathways of protein import (2023, Nature)
  • Mitochondrial protein transport: Versatility of translocases and mechanisms (2023, Molecular Cell)
  • Mitochondrial sorting and assembly machinery operates by β-barrel switching (2021, Nature)
  • Central role of Tim17 in mitochondrial presequence protein translocation (2023, Nature)

Collaboration is a notable aspect of Wiedemann's work with frequent co-authors including Nikolaus Pfanner, Jon V. Busto, Thomas Becker, Iniyan Ganesan, and Conny Steiert. The number of joint publications with these colleagues reflects established research partnerships.

Best Publications

  • Mitochondrial Machineries for Protein Import and Assembly.

    Nils Wiedemann;Nikolaus Pfanner

  • Mitochondrial proteins: from biogenesis to functional networks

    Nikolaus Pfanner;Bettina Warscheid;Nils Wiedemann

  • Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins.

    Agnieszka Chacinska;Sylvia Pfannschmidt;Nils Wiedemann;Vera Kozjak

  • Machinery for protein sorting and assembly in the mitochondrial outer membrane

    Nils Wiedemann;Vera Kozjak;Agnieszka Chacinska;Birgit Schönfisch

  • The protein import machinery of mitochondria.

    Nils Wiedemann;Ann E. Frazier;Nikolaus Pfanner

  • Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale

    Marcel Morgenstern;Sebastian B. Stiller;Philipp Lübbert;Christian D. Peikert

  • An essential role of Sam50 in the protein sorting and assembly machinery of the mitochondrial outer membrane.

    Vera Kozjak;Nils Wiedemann;Dusanka Milenkovic;Christiane Lohaus

  • Dissecting Membrane Insertion of Mitochondrial β-Barrel Proteins

    Stephan Kutik;Diana Stojanovski;Lars Becker;Thomas Becker

  • The Mitochondrial Presequence Translocase: An Essential Role of Tim50 in Directing Preproteins to the Import Channel

    Andreas Geissler;Agnieszka Chacinska;Kaye N. Truscott;Nils Wiedemann

  • The Mitochondrial Morphology Protein Mdm10 Functions in Assembly of the Preprotein Translocase of the Outer Membrane

    Chris Meisinger;Michael Rissler;Agnieszka Chacinska;Luiza K.Sanjuán Szklarz

  • The three modules of ADP/ATP carrier cooperate in receptor recruitment and translocation into mitochondria

    Nils Wiedemann;Nikolaus Pfanner;Michael T. Ryan;Michael T. Ryan

  • Mitochondrial Cardiolipin Involved in Outer-Membrane Protein Biogenesis: Implications for Barth Syndrome

    Natalia Gebert;Amit S. Joshi;Stephan Kutik;Thomas Becker

  • Essential role of Isd11 in mitochondrial iron–sulfur cluster synthesis on Isu scaffold proteins

    Nils Wiedemann;Eugen Urzica;Bernard Guiard;Hanne Müller

  • Assembling the mitochondrial outer membrane

    Nikolaus Pfanner;Nils Wiedemann;Chris Meisinger;Trevor James Lithgow

  • Multistep assembly of the protein import channel of the mitochondrial outer membrane.

    Kirstin Model;Chris Meisinger;Thorsten Prinz;Nils Wiedemann

  • Molecular architecture of the active mitochondrial protein gate

    Takuya Shiota;Takuya Shiota;Kenichiro Imai;Jian Qiu;Victoria L Hewitt

  • Biogenesis of the protein import channel Tom40 of the mitochondrial outer membrane: intermembrane space components are involved in an early stage of the assembly pathway.

    Nils. Wiedemann;Kaye Narelle. Truscott;Sylvia. Pfannschmidt;Bernard. Guiard

  • The essential mitochondrial protein Erv1 cooperates with Mia40 in biogenesis of intermembrane space proteins.

    Michael Rissler;Nils Wiedemann;Sylvia Pfannschmidt;Kipros Gabriel

  • A Role for Tim21 in Membrane-Potential-Dependent Preprotein Sorting in Mitochondria

    Martin van der Laan;Nils Wiedemann;David U. Mick;Bernard Guiard

  • Amyloid-β Peptide Induces Mitochondrial Dysfunction by Inhibition of Preprotein Maturation

    Dirk Mossmann;F.-Nora Vögtle;Asli Aras Taskin;Pedro Filipe Teixeira

Frequent Co-Authors

Nikolaus Pfanner
Nikolaus Pfanner University of Freiburg
Chris Meisinger
Chris Meisinger University of Freiburg
Bernard Guiard
Bernard Guiard Centre national de la recherche scientifique, CNRS
Thomas Becker
Thomas Becker Ludwig-Maximilians-Universität München
Martin van der Laan
Martin van der Laan Saarland University
Peter Rehling
Peter Rehling University of Göttingen
Bettina Warscheid
Bettina Warscheid University of Freiburg
Agnieszka Chacinska
Agnieszka Chacinska IMol Polish Academy of Sciences
Michael T. Ryan
Michael T. Ryan University of Sydney
Helmut E. Meyer
Helmut E. Meyer Ruhr University Bochum

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