Gregory L. Challis

Research.com Recognitions

• 2017 - Interdisciplinary Prize, Royal Society of Chemistry (UK)
• 2002 - Meldola Medal and Prize, Royal Society of Chemistry (UK)

Overview

Best Publications

• Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

  S. D. Bentley;K. F. Chater;A.-M. Cerdeño-Tárraga;G. L. Challis;G. L. Challis

  4179
  Citations

• Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature

  Paul G. Arnison;Mervyn J. Bibb;Gabriele Bierbaum;Albert Alexander Bowers

  2194
  Citations

• Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains.

  Gregory L Challis;Jacques Ravel;Craig A Townsend

  970
  Citations

• Discovery of microbial natural products by activation of silent biosynthetic gene clusters.

  Peter J. Rutledge;Gregory L. Challis

  899
  Citations

• Synergy and contingency as driving forces for the evolution of multiple secondary metabolite production by Streptomyces species

  Gregory L. Challis;David A. Hopwood

  820
  Citations

• Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens

  Mark W. Silby;Ana M. Cerdeño-Tárraga;Georgios S. Vernikos;Stephen R. Giddens

  482
  Citations

• Discovery of a new peptide natural product by Streptomyces coelicolor genome mining.

  Sylvie Lautru;Robert J Deeth;Lianne M Bailey;Gregory L Challis

  469
  Citations

• Strategies for the discovery of new natural products by genome mining.

  Malek Zerikly;Gregory L. Challis

  388
  Citations

• A widely distributed bacterial pathway for siderophore biosynthesis independent of nonribosomal peptide synthetases.

  Gregory L. Challis

  381
  Citations

• Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens

  Luisa Laureti;Lijiang Song;Sheng Huang;Sheng Huang;Christophe Corre

  380
  Citations

• Identification of a cluster of genes that directs desferrioxamine biosynthesis in Streptomyces coelicolor M145.

  Francisco Barona-Gómez;Ursula Wong;Anastassios E Giannakopulos;Peter J Derrick

  322
  Citations

• Mining microbial genomes for new natural products and biosynthetic pathways.

  Gregory L. Challis

  320
  Citations

• Coelichelin, a new peptide siderophore encoded by the Streptomyces coelicolor genome: structure prediction from the sequence of its non‐ribosomal peptide synthetase

  Gregory L. Challis;Jacques Ravel

  266
  Citations

• The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081.

  Nicholas R. Thomson;Sarah Howard;Brendan W. Wren;Matthew T. G. Holden

  260
  Citations

• Genome Mining for Novel Natural Product Discovery

  Gregory L. Challis

  255
  Citations

• Mechanism and Catalytic Diversity of Rieske Non-Heme Iron-Dependent Oxygenases.

  Sarah M. Barry;Gregory L. Challis

  254
  Citations

• Analysis of the prodiginine biosynthesis gene cluster of Streptomyces coelicolor A3(2): new mechanisms for chain initiation and termination in modular multienzymes

  Ana M. Cerdeño;Mervyn J. Bibb;Gregory L. Challis

  249
  Citations

• Cytochrome P450–catalyzed L -tryptophan nitration in thaxtomin phytotoxin biosynthesis

  Sarah M Barry;Johan A Kers;Johan A Kers;Evan G Johnson;Evan G Johnson;Lijiang Song

  244
  Citations

• The dynamic architecture of the metabolic switch in Streptomyces coelicolor

  Kay Nieselt;Florian Battke;Alexander Herbig;Per Bruheim;Per Bruheim

  206
  Citations

• Recent advances in siderophore biosynthesis

  Sarah M Barry;Gregory L Challis

  205
  Citations