What is he best known for?
The fields of study he is best known for:
Gregory L. Challis mostly deals with Biochemistry, Gene, Streptomyces coelicolor, Genome and Genetics.
While the research belongs to areas of Streptomyces coelicolor, Gregory L. Challis spends his time largely on the problem of Gene cluster, intersecting his research to questions surrounding Polyketide, Microbiology, Plasmid and Quorum sensing.
The study incorporates disciplines such as Natural product and Computational biology in addition to Genome.
His work in Genomics, Whole genome sequencing, Regulator gene and DNA sequencing is related to Genetics.
His Regulator gene study combines topics from a wide range of disciplines, such as Genome project and Synteny.
The Biosynthesis study combines topics in areas such as Streptomycetaceae, Siderophore and Streptomyces.
His most cited work include:
- Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2) (2606 citations)
- Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2) (2606 citations)
- Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature (1048 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Biochemistry, Biosynthesis, Stereochemistry, Gene and Gene cluster.
His study looks at the intersection of Biosynthesis and topics like Cytochrome P450 with Pentamycin.
His work in Stereochemistry covers topics such as Substrate which are related to areas like Active site.
His research in Gene is mostly concerned with Genome.
His Genome research focuses on Whole genome sequencing in particular.
His research in Gene cluster intersects with topics in Operon and Mutant.
He most often published in these fields:
- Biochemistry (49.20%)
- Biosynthesis (44.92%)
- Stereochemistry (38.50%)
What were the highlights of his more recent work (between 2018-2021)?
- Gene (36.36%)
- Biosynthesis (44.92%)
- Polyketide (27.81%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Gene, Biosynthesis, Polyketide, Stereochemistry and Gene cluster.
Gregory L. Challis studies Gene, focusing on Genome in particular.
His studies deal with areas such as Sesquiterpene, Cyclase and Saccharomyces cerevisiae as well as Biosynthesis.
Many of his research projects under Polyketide are closely connected to Domain with Domain, tying the diverse disciplines of science together.
His Stereochemistry study combines topics in areas such as Substrate, Thioester, Condensation domain and Active site.
His Gene cluster study is focused on Biochemistry in general.
Between 2018 and 2021, his most popular works were:
- Genome mining identifies cepacin as a plant-protective metabolite of the biopesticidal bacterium Burkholderia ambifaria (38 citations)
- Genome mining identifies cepacin as a plant-protective metabolite of the biopesticidal bacterium Burkholderia ambifaria (38 citations)
- Developmentally regulated volatiles geosmin and 2-methylisoborneol attract a soil arthropod to Streptomyces bacteria promoting spore dispersal (22 citations)
In his most recent research, the most cited papers focused on:
Gregory L. Challis spends much of his time researching Condensation domain, Stereochemistry, Docking, Polyketide synthase and Polyketide.
His Condensation domain study deals with the bigger picture of Gene.
His Docking research is multidisciplinary, incorporating elements of Transport protein, Short linear motif, Hydroxylation, Oxidoreductase and Cofactor.
His Cofactor research incorporates themes from Heme and Active site.
The concepts of his Polyketide synthase study are interwoven with issues in Thioester, Transacylation, Acyl carrier protein and Acylation.
His Polyketide research is multidisciplinary, incorporating perspectives in Protein subunit and Peptide.
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