The scientist’s investigation covers issues in Biochemistry, Peptide, Computational biology, Plantazolicin and Gene cluster. His Enzyme, Growth inhibition and Pharmacophore study, which is part of a larger body of work in Biochemistry, is frequently linked to Cdc25, bridging the gap between disciplines. His Peptide research incorporates themes from Protein structure, Plasma protein binding, Biosynthesis and Protein biosynthesis.
His work in Computational biology addresses subjects such as Genome mining, which are connected to disciplines such as Nosiheptide and Biotechnology. His study looks at the intersection of Plantazolicin and topics like Bacteriocin with Toxin, Streptococcus pyogenes, Bacillaceae and Bacillus amyloliquefaciens. The subject of his Gene cluster research is within the realm of Gene.
Douglas A. Mitchell mainly focuses on Biochemistry, Peptide, Enzyme, Biosynthesis and Computational biology. His Biochemistry research includes themes of Nitric oxide and Plantazolicin. His work carried out in the field of Peptide brings together such families of science as Ribosomal RNA, Peptide sequence, Signal peptide and Stereochemistry.
His work on Substrate as part of general Enzyme research is frequently linked to Post translational, thereby connecting diverse disciplines of science. His studies deal with areas such as In vitro, Antibiotics, Microbiology, Function and Combinatorial chemistry as well as Biosynthesis. The various areas that Douglas A. Mitchell examines in his Computational biology study include Genome mining, Gene cluster, Gene, Antibiotic resistance and Natural product.
His main research concerns Peptide, Gene, Computational biology, Enzyme and Biosynthesis. His research in Peptide intersects with topics in Peptide sequence, Stereochemistry, Heterologous expression and Threonine. His Gene study is associated with Biochemistry.
His Computational biology study integrates concerns from other disciplines, such as UniProt and Genome mining. The Substrate, Reductase and Active site research Douglas A. Mitchell does as part of his general Enzyme study is frequently linked to other disciplines of science, such as Orchestration, therefore creating a link between diverse domains of science. His Biosynthesis research is multidisciplinary, relying on both Combinatorial chemistry, Antibiotics, Microbiology and Function.
His scientific interests lie mostly in Computational biology, Peptide, Enzyme, Extramural and Genome mining. He interconnects Euryarchaeota, Phylum, Gene, Archaea and RefSeq in the investigation of issues within Computational biology. His studies in Peptide integrate themes in fields like Peptide sequence and Stereochemistry.
The study incorporates disciplines such as Protein database and UniProt in addition to Genome mining. His work in Combinatorial chemistry tackles topics such as Biosynthesis which are related to areas like Threonine, Thioether and Gene cluster. His Active site study introduces a deeper knowledge of Biochemistry.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature
Paul G. Arnison;Mervyn J. Bibb;Gabriele Bierbaum;Albert Alexander Bowers.
Natural Product Reports (2013)
antiSMASH 4.0-improvements in chemistry prediction and gene cluster boundary identification.
Kai Blin;Thomas Wolf;Marc G. Chevrette;Xiaowen Lu.
Nucleic Acids Research (2017)
Minimum Information about a Biosynthetic Gene cluster.
Marnix H. Medema;Marnix H. Medema;Renzo Kottmann;Pelin Yilmaz;Matthew Cummings.
Nature Chemical Biology (2015)
Thioredoxin catalyzes the S-nitrosation of the caspase-3 active site cysteine.
Douglas Alan Mitchell;Michael A. Marletta;Michael A. Marletta.
Nature Chemical Biology (2005)
A new genome-mining tool redefines the lasso peptide biosynthetic landscape
Jonathan I. Tietz;Christopher J. Schwalen;Parth S. Patel;Tucker Maxson.
Nature Chemical Biology (2017)
A prevalent peptide-binding domain guides ribosomal natural product biosynthesis
Brandon J Burkhart;Graham A Hudson;Kyle L Dunbar;Douglas A Mitchell.
Nature Chemical Biology (2015)
Discovery of a widely distributed toxin biosynthetic gene cluster
Shaun W. Lee;Douglas A. Mitchell;Andrew L. Markley;Mary E. Hensler.
Proceedings of the National Academy of Sciences of the United States of America (2008)
New developments in RiPP discovery, enzymology and engineering
Manuel Montalbán-López;Thomas A Scott;Sangeetha Ramesh;Imran R Rahman.
Natural Product Reports (2021)
Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases
Kai Li;Lici A. Schurig-Briccio;Xinxin Feng;Ashutosh Upadhyay.
Journal of Medicinal Chemistry (2014)
Identification of a Potent and Selective Pharmacophore for Cdc25 Dual Specificity Phosphatase Inhibitors.
John S. Lazo;Kaoru Nemoto;Katharine E. Pestell;Kathleen Cooley.
Molecular Pharmacology (2002)
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