D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 49 Citations 9,730 104 World Ranking 13571 National Ranking 5744

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Bacteria

The scientist’s investigation covers issues in Biochemistry, Peptide, Computational biology, Plantazolicin and Gene cluster. His Enzyme, Growth inhibition and Pharmacophore study, which is part of a larger body of work in Biochemistry, is frequently linked to Cdc25, bridging the gap between disciplines. His Peptide research incorporates themes from Protein structure, Plasma protein binding, Biosynthesis and Protein biosynthesis.

His work in Computational biology addresses subjects such as Genome mining, which are connected to disciplines such as Nosiheptide and Biotechnology. His study looks at the intersection of Plantazolicin and topics like Bacteriocin with Toxin, Streptococcus pyogenes, Bacillaceae and Bacillus amyloliquefaciens. The subject of his Gene cluster research is within the realm of Gene.

His most cited work include:

  • Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature (1048 citations)
  • antiSMASH 4.0-improvements in chemistry prediction and gene cluster boundary identification. (721 citations)
  • Minimum Information about a Biosynthetic Gene cluster. (418 citations)

What are the main themes of his work throughout his whole career to date?

Douglas A. Mitchell mainly focuses on Biochemistry, Peptide, Enzyme, Biosynthesis and Computational biology. His Biochemistry research includes themes of Nitric oxide and Plantazolicin. His work carried out in the field of Peptide brings together such families of science as Ribosomal RNA, Peptide sequence, Signal peptide and Stereochemistry.

His work on Substrate as part of general Enzyme research is frequently linked to Post translational, thereby connecting diverse disciplines of science. His studies deal with areas such as In vitro, Antibiotics, Microbiology, Function and Combinatorial chemistry as well as Biosynthesis. The various areas that Douglas A. Mitchell examines in his Computational biology study include Genome mining, Gene cluster, Gene, Antibiotic resistance and Natural product.

He most often published in these fields:

  • Biochemistry (40.74%)
  • Peptide (35.19%)
  • Enzyme (27.78%)

What were the highlights of his more recent work (between 2018-2021)?

  • Peptide (35.19%)
  • Gene (18.52%)
  • Computational biology (25.00%)

In recent papers he was focusing on the following fields of study:

His main research concerns Peptide, Gene, Computational biology, Enzyme and Biosynthesis. His research in Peptide intersects with topics in Peptide sequence, Stereochemistry, Heterologous expression and Threonine. His Gene study is associated with Biochemistry.

His Computational biology study integrates concerns from other disciplines, such as UniProt and Genome mining. The Substrate, Reductase and Active site research Douglas A. Mitchell does as part of his general Enzyme study is frequently linked to other disciplines of science, such as Orchestration, therefore creating a link between diverse domains of science. His Biosynthesis research is multidisciplinary, relying on both Combinatorial chemistry, Antibiotics, Microbiology and Function.

Between 2018 and 2021, his most popular works were:

  • New developments in RiPP discovery, enzymology and engineering (43 citations)
  • Bioinformatic Mapping of Radical S-Adenosylmethionine-Dependent Ribosomally Synthesized and Post-Translationally Modified Peptides Identifies New Cα, Cβ, and Cγ-Linked Thioether-Containing Peptides (38 citations)
  • Enzymatic Reconstitution and Biosynthetic Investigation of the Lasso Peptide Fusilassin. (28 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Bacteria

His scientific interests lie mostly in Computational biology, Peptide, Enzyme, Extramural and Genome mining. He interconnects Euryarchaeota, Phylum, Gene, Archaea and RefSeq in the investigation of issues within Computational biology. His studies in Peptide integrate themes in fields like Peptide sequence and Stereochemistry.

The study incorporates disciplines such as Protein database and UniProt in addition to Genome mining. His work in Combinatorial chemistry tackles topics such as Biosynthesis which are related to areas like Threonine, Thioether and Gene cluster. His Active site study introduces a deeper knowledge of Biochemistry.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature

Paul G. Arnison;Mervyn J. Bibb;Gabriele Bierbaum;Albert Alexander Bowers.
Natural Product Reports (2013)

1636 Citations

antiSMASH 4.0-improvements in chemistry prediction and gene cluster boundary identification.

Kai Blin;Thomas Wolf;Marc G. Chevrette;Xiaowen Lu.
Nucleic Acids Research (2017)

1055 Citations

Minimum Information about a Biosynthetic Gene cluster.

Marnix H. Medema;Marnix H. Medema;Renzo Kottmann;Pelin Yilmaz;Matthew Cummings.
Nature Chemical Biology (2015)

654 Citations

Thioredoxin catalyzes the S-nitrosation of the caspase-3 active site cysteine.

Douglas Alan Mitchell;Michael A. Marletta;Michael A. Marletta.
Nature Chemical Biology (2005)

304 Citations

A new genome-mining tool redefines the lasso peptide biosynthetic landscape

Jonathan I. Tietz;Christopher J. Schwalen;Parth S. Patel;Tucker Maxson.
Nature Chemical Biology (2017)

281 Citations

A prevalent peptide-binding domain guides ribosomal natural product biosynthesis

Brandon J Burkhart;Graham A Hudson;Kyle L Dunbar;Douglas A Mitchell.
Nature Chemical Biology (2015)

250 Citations

Discovery of a widely distributed toxin biosynthetic gene cluster

Shaun W. Lee;Douglas A. Mitchell;Andrew L. Markley;Mary E. Hensler.
Proceedings of the National Academy of Sciences of the United States of America (2008)

235 Citations

New developments in RiPP discovery, enzymology and engineering

Manuel Montalbán-López;Thomas A Scott;Sangeetha Ramesh;Imran R Rahman.
Natural Product Reports (2021)

231 Citations

Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases

Kai Li;Lici A. Schurig-Briccio;Xinxin Feng;Ashutosh Upadhyay.
Journal of Medicinal Chemistry (2014)

218 Citations

Identification of a Potent and Selective Pharmacophore for Cdc25 Dual Specificity Phosphatase Inhibitors.

John S. Lazo;Kaoru Nemoto;Katharine E. Pestell;Kathleen Cooley.
Molecular Pharmacology (2002)

216 Citations

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