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Genetics
Russia
2024
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Genetics and Molecular Biology
Russia
2024

D-Index & Metrics

Genetics

D-Index
83
Citations
32774
World Ranking
1400
National Ranking
662

Molecular Biology

D-Index
83
Citations
32774
World Ranking
889
National Ranking
469

Research.com Recognitions

  • 2024 - Research.com Genetics in Russia Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Russia Leader Award
  • 2023 - Research.com Genetics in Russia Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Russia Leader Award

Overview

Konstantin Severinov is affiliated with Rutgers, The State University of New Jersey in the United States. Their research primarily falls within the broad field of Biochemistry, Genetics and Molecular Biology, with particular focus on Molecular Biology, Ecology, Genetics, Plant Science, and Endocrinology.

Severinov's work encompasses a range of topics, including:

  • Bacteriophages and microbial interactions
  • RNA and protein synthesis mechanisms
  • CRISPR and Genetic Engineering
  • Bacterial Genetics and Biotechnology
  • Genomics and Phylogenetic Studies
  • Vibrio bacteria research studies
  • Plant Virus Research Studies

Their recent publications reflect these interests and include:

  • New developments in RiPP discovery, enzymology and engineering, 2020, Natural Product Reports
  • Phage T7 DNA mimic protein Ocr is a potent inhibitor of BREX defence, 2020, Nucleic Acids Research
  • Hyperbranched poly(β-amino ester) based polyplex nanopaticles for delivery of CRISPR/Cas9 system and treatment of HPV infection associated cervical cancer, 2020, Journal of Controlled Release
  • Efficient target cleavage by Type V Cas12a effectors programmed with split CRISPR RNA, 2021, Nucleic Acids Research
  • Bacteriostatic antibiotics promote CRISPR-Cas adaptive immunity by enabling increased spacer acquisition, 2021, Cell Host & Microbe

Severinov frequently publishes in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Viruses
  • mBio
  • Nature Communications

The scientist collaborates extensively with colleagues, notably:

  • Artem Isaev
  • Sergei Borukhov
  • Olga Musharova
  • Svetlana Dubiley
  • Natalia Morozova

Best Publications

  • Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature

    Paul G. Arnison;Mervyn J. Bibb;Gabriele Bierbaum;Albert Alexander Bowers

  • C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

    Omar O. Abudayyeh;Jonathan S. Gootenberg;Silvana Konermann;Silvana Konermann;Silvana Konermann;Julia Joung;Julia Joung;Julia Joung

  • Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems

    Sergey Shmakov;Omar O. Abudayyeh;Kira S. Makarova;Yuri I. Wolf

  • Crystal Structure of Thermus aquaticus Core RNA Polymerase at 3.3 Å Resolution

    Gongyi Zhang;Elizabeth A Campbell;Leonid Minakhin;Catherine Richter

  • Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence

    Ekaterina Semenova;Matthijs M. Jore;Kirill A. Datsenko;Anna Semenova

  • A third recognition element in bacterial promoters: DNA binding by the alpha subunit of RNA polymerase

    Wilma Ross;Khoosheh K. Gosink;Julia Salomon;Kazuhiko Igarashi

  • Diversity and evolution of class 2 CRISPR-Cas systems

    Sergey Shmakov;Aaron Smargon;David Scott;David Cox

  • Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array

    Bernd Zetsche;Matthias Heidenreich;Prarthana Mohanraju;Iana Fedorova

  • New developments in RiPP discovery, enzymology and engineering

    Manuel Montalbán-López;Thomas A Scott;Sangeetha Ramesh;Imran R Rahman

  • CRISPR Immunity Relies on the Consecutive Binding and Degradation of Negatively Supercoiled Invader DNA by Cascade and Cas3

    Edze R. Westra;Paul B.G. van Erp;Tim Künne;Shi Pey Wong

  • Molecular memory of prior infections activates the CRISPR/Cas adaptive bacterial immunity system

    Kirill A. Datsenko;Ksenia Pougach;Anton Tikhonov;Barry L. Wanner

  • Escherichia coli CspA-family RNA chaperones are transcription antiterminators.

    Weonhye Bae;Bing Xia;Masayori Inouye;Konstantin Severinov

  • Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly.

    Leonid Minakhin;Sechal Bhagat;Adrian Brunning;Elizabeth A. Campbell

  • Transcription, Processing, and Function of CRISPR Cassettes in Escherichia coli

    Ksenia Pougach;Ekaterina Semenova;Ekaterina Bogdanova;Kirill A. Datsenko

  • Type I-E CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition.

    Edze R. Westra;Ekaterina Semenova;Kirill A. Datsenko;Ryan N. Jackson

  • Expressed protein ligation, a novel method for studying protein-protein interactions in transcription

    Konstantin Severinov;Tom W. Muir

  • Structure of microcin J25, a peptide inhibitor of bacterial RNA polymerase, is a lassoed tail.

    Kelly Anne Wilson;Markus Kalkum;Jennifer Ottesen;Julia Yuzenkova

  • Genome-wide identification of regulatory RNAs in the human pathogen Clostridium difficile.

    Olga A. Soutourina;Olga A. Soutourina;Marc Monot;Pierre Boudry;Pierre Boudry;Laure Saujet;Laure Saujet

  • Rifampicin region revisited. New rifampicin-resistant and streptolydigin-resistant mutants in the beta subunit of Escherichia coli RNA polymerase.

    K Severinov;M Soushko;A Goldfarb;V Nikiforov

  • CRISPR enzymes and systems

    Konstantin Severinov;Feng Zhang;Yuri I. Wolf;Sergey Shmakov

Frequent Co-Authors

Seth A. Darst
Seth A. Darst Rockefeller University
Kira S. Makarova
Kira S. Makarova National Institutes of Health
Eugene V. Koonin
Eugene V. Koonin National Institutes of Health
Satish K. Nair
Satish K. Nair University of Illinois at Urbana-Champaign
Yuri I. Wolf
Yuri I. Wolf National Institutes of Health
Alex Goldfarb
Alex Goldfarb Inozyme Pharma
Tomasz Heyduk
Tomasz Heyduk Saint Louis University
Martin Buck
Martin Buck Imperial College London
Mikhail S. Gelfand
Mikhail S. Gelfand Skolkovo Institute of Science and Technology
Robert Landick
Robert Landick University of Wisconsin–Madison

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