H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 83 Citations 34,270 435 World Ranking 882 National Ranking 2

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

Konstantin Severinov mostly deals with Genetics, CRISPR, RNA polymerase, Biochemistry and Molecular biology. His work in Genetics is not limited to one particular discipline; it also encompasses Computational biology. His CRISPR study combines topics in areas such as Genome and DNA.

His study in RNA polymerase is interdisciplinary in nature, drawing from both RNA polymerase II and Polymerase. His biological study spans a wide range of topics, including Specificity factor, Protein subunit, Mutant, Escherichia coli and RNA polymerase I. The various areas that Konstantin Severinov examines in his Trans-activating crRNA study include Nuclease and Effector.

His most cited work include:

  • Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature (1048 citations)
  • C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector (859 citations)
  • Crystal Structure of Thermus aquaticus Core RNA Polymerase at 3.3 Å Resolution (717 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in RNA polymerase, Genetics, Biochemistry, Transcription and Molecular biology. Konstantin Severinov has researched RNA polymerase in several fields, including Promoter, RNA polymerase II, Polymerase and Cell biology. His Genetics research focuses on CRISPR, Gene, Bacteriophage, Genome and CRISPR interference.

His research integrates issues of RNA, Computational biology and DNA in his study of CRISPR. His study in Transcription is interdisciplinary in nature, drawing from both Gene expression, Transcription factor, Peptide sequence, Protein structure and Binding site. In his research on the topic of Molecular biology, Abortive initiation is strongly related with Response element.

He most often published in these fields:

  • RNA polymerase (51.57%)
  • Genetics (52.12%)
  • Biochemistry (49.72%)

What were the highlights of his more recent work (between 2018-2021)?

  • DNA (42.36%)
  • CRISPR (50.09%)
  • Gene (37.57%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in DNA, CRISPR, Gene, Escherichia coli and Computational biology. His study with DNA involves better knowledge in Genetics. His CRISPR research includes elements of Mobile genetic elements, Nuclease and Effector.

His Escherichia coli research is multidisciplinary, incorporating elements of Interference and CRISPR interference. The Computational biology study combines topics in areas such as Acquired immune system, Nucleic acid, Genome, Cas9 and Locus. The Genome engineering research Konstantin Severinov does as part of his general Cas9 study is frequently linked to other disciplines of science, such as Clostridium cellulolyticum, therefore creating a link between diverse domains of science.

Between 2018 and 2021, his most popular works were:

  • New developments in RiPP discovery, enzymology and engineering (43 citations)
  • Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids (19 citations)
  • Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids (19 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

DNA, Genome, CRISPR, Gene and Escherichia coli are his primary areas of study. His DNA research incorporates elements of Bacteriophage and Transcription. His CRISPR study integrates concerns from other disciplines, such as RNA, Effector, Cell biology and Computational biology.

His work in the fields of Methylation, Plasmid and Genome editing overlaps with other areas such as Animal health. Plasmid is a primary field of his research addressed under Genetics. His Escherichia coli research includes themes of Acquired immune system, Interference, CRISPR interference, Prokaryotic translation and Peptide.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature

Paul G. Arnison;Mervyn J. Bibb;Gabriele Bierbaum;Albert Alexander Bowers.
Natural Product Reports (2013)

1355 Citations

Crystal Structure of Thermus aquaticus Core RNA Polymerase at 3.3 Å Resolution

Gongyi Zhang;Elizabeth A Campbell;Leonid Minakhin;Catherine Richter.
Cell (1999)

987 Citations

A third recognition element in bacterial promoters: DNA binding by the alpha subunit of RNA polymerase

Wilma Ross;Khoosheh K. Gosink;Julia Salomon;Kazuhiko Igarashi.
Science (1993)

927 Citations

Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence

Ekaterina Semenova;Matthijs M. Jore;Kirill A. Datsenko;Anna Semenova.
Proceedings of the National Academy of Sciences of the United States of America (2011)

802 Citations

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

Omar O. Abudayyeh;Jonathan S. Gootenberg;Silvana Konermann;Julia Joung;Julia Joung;Julia Joung.
Science (2016)

756 Citations

Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems

Sergey Shmakov;Omar O. Abudayyeh;Kira S. Makarova;Yuri I. Wolf.
Molecular Cell (2015)

743 Citations

CRISPR Immunity Relies on the Consecutive Binding and Degradation of Negatively Supercoiled Invader DNA by Cascade and Cas3

Edze R. Westra;Paul B.G. van Erp;Tim Künne;Shi Pey Wong.
Molecular Cell (2012)

574 Citations

Diversity and evolution of class 2 CRISPR-Cas systems

Sergey Shmakov;Aaron Smargon;David Scott;David Cox.
Nature Reviews Microbiology (2017)

530 Citations

Molecular memory of prior infections activates the CRISPR/Cas adaptive bacterial immunity system

Kirill A. Datsenko;Ksenia Pougach;Anton Tikhonov;Barry L. Wanner.
Nature Communications (2012)

526 Citations

Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array

Bernd Zetsche;Matthias Heidenreich;Prarthana Mohanraju;Iana Fedorova.
Nature Biotechnology (2017)

515 Citations

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Best Scientists Citing Konstantin Severinov

Eugene V. Koonin

Eugene V. Koonin

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Robert Landick

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Seth A. Darst

Rockefeller University

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Jennifer A. Doudna

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Fudan University

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Richard H. Ebright

Richard H. Ebright

Rutgers, The State University of New Jersey

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Rodolphe Barrangou

Rodolphe Barrangou

North Carolina State University

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Richard L. Gourse

Richard L. Gourse

University of Wisconsin–Madison

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Martin Buck

Martin Buck

Imperial College London

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Stan J. J. Brouns

Stan J. J. Brouns

Delft University of Technology

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Irina Artsimovitch

The Ohio State University

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Luciano A. Marraffini

Rockefeller University

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Akira Ishihama

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Douglas A. Mitchell

University of Illinois at Urbana-Champaign

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David R. Liu

David R. Liu

Harvard University

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