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Microbiology

D-Index
77
Citations
20020
World Ranking
1358
National Ranking
593

Molecular Biology

D-Index
77
Citations
19854
World Ranking
1115
National Ranking
576

Research.com Recognitions

  • 2014 - Fellow of the American Academy of Arts and Sciences
  • 2003 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Richard L. Gourse is affiliated with the University of Wisconsin-Madison in the United States. Their research primarily focuses on Biochemistry, Genetics and Molecular Biology, with significant contributions in the subfields of Molecular Biology, Genetics, Ecology, and Structural Biology.

The scientist's work covers several main topics including:

  • RNA and protein synthesis mechanisms
  • Bacterial Genetics and Biotechnology
  • RNA modifications and cancer
  • Microbial Metabolic Engineering and Bioproduction
  • Bacteriophages and microbial interactions
  • RNA Research and Splicing
  • Advanced Electron Microscopy Techniques and Applications

Recent published papers by Richard L. Gourse include:

  • "Stepwise Promoter Melting by Bacterial RNA Polymerase," 2020, Molecular Cell
  • "Reverse engineering of fatty acid-tolerant Escherichia coli identifies design strategies for robust microbial cell factories," 2020, Metabolic Engineering
  • "A majority of Rhodobacter sphaeroides promoters lack a crucial RNA polymerase recognition feature, enabling coordinated transcription activation," 2020, Proceedings of the National Academy of Sciences
  • "Guanosine Tetraphosphate Has a Similar Affinity for Each of Its Two Binding Sites on Escherichia coli RNA Polymerase," 2020, Frontiers in Microbiology
  • "Rhodobacter sphaeroides CarD Negatively Regulates Its Own Promoter," 2021, Journal of Bacteriology

Frequent co-authors associated with their work are:

  • Wilma Ross
  • Jonathan Jagodnik
  • Saumya Gopalkrishnan
  • Kemardo K. Henry
  • James Chen

Their research outputs have appeared repeatedly in several publication venues including:

  • Proceedings of the National Academy of Sciences
  • Molecular Cell
  • Metabolic Engineering
  • Frontiers in Microbiology
  • Journal of Bacteriology

Richard L. Gourse's contributions have been recognized by their peers through awards such as:

  • Fellow of the American Academy of Arts and Sciences (2014)
  • Fellow of the American Association for the Advancement of Science (AAAS) (2003)

Best Publications

  • Regulation of the Synthesis of Ribosomes and Ribosomal Components

    Masayasu Nomura;Richard Gourse;Gail Baughman

  • A third recognition element in bacterial promoters: DNA binding by the alpha subunit of RNA polymerase

    Wilma Ross;Khoosheh K. Gosink;Julia Salomon;Kazuhiko Igarashi

  • DksA: a critical component of the transcription initiation machinery that potentiates the regulation of rRNA promoters by ppGpp and the initiating NTP.

    Brian J. Paul;Melanie M. Barker;Wilma Ross;David A. Schneider

  • E.coli Fis protein activates ribosomal RNA transcription in vitro and in vivo.

    W Ross;J F Thompson;J T Newlands;R L Gourse

  • Transcription regulation by initiating NTP concentration: rRna synthesis in bacteria

    Tamas Gaal;Michael S. Bartlett;Wilma Ross;Charles L. Turnbough

  • Mechanism of regulation of transcription initiation by ppGpp. I. Effects of ppGpp on transcription initiation in vivo and in vitro.

    Melanie M. Barker;Tamas Gaal;Cathleen A. Josaitis;Richard L. Gourse

  • rRNA transcription in Escherichia coli

    Brian J. Paul;Wilma Ross;Tamas Gaal;Richard L. Gourse

  • DksA potentiates direct activation of amino acid promoters by ppGpp

    Brian J. Paul;Melanie B. Berkmen;Richard L. Gourse

  • Identification of an UP element consensus sequence for bacterial promoters

    Shawn T. Estrem;Tamas Gaal;Wilma Ross;Richard L. Gourse

  • Advances in bacterial promoter recognition and its control by factors that do not bind DNA.

    Shanil P. Haugen;Wilma Ross;Richard L. Gourse

  • UPs and downs in bacterial transcription initiation: the role of the alpha subunit of RNA polymerase in promoter recognition.

    Richard L. Gourse;Wilma Ross;Tamas Gaal

  • DNA determinants of rRNA synthesis in E. coli: Growth rate dependent regulation, feedback inhibition, upstream activation, antitermination

    Richard L. Gourse;Herman A. de Boer;Masayasu Nomura

  • An alternative strategy for bacterial ribosome synthesis: Bacillus subtilis rRNA transcription regulation

    Libor Krásný;Richard L Gourse

  • rRNA TRANSCRIPTION AND GROWTH RATE–DEPENDENT REGULATION OF RIBOSOME SYNTHESIS IN ESCHERICHIA COLI

    R L Gourse;T Gaal;M S Bartlett;J A Appleman

  • Domain organization of RNA polymerase α subunit: C-terminal 85 amino acids constitute a domain capable of dimerization and DNA binding

    Erich E. Blatter;Wilma Ross;Hong Tang;Richard L. Gourse

  • The Magic Spot: A ppGpp Binding Site on E. coli RNA Polymerase Responsible for Regulation of Transcription Initiation

    Wilma Ross;Catherine E. Vrentas;Patricia Sanchez-Vazquez;Tamas Gaal

  • ppGpp Binding to a Site at the RNAP-DksA Interface Accounts for Its Dramatic Effects on Transcription Initiation during the Stringent Response

    Wilma Ross;Patricia Sanchez-Vazquez;Albert Y. Chen;Jeong-Hyun Lee

  • Factor Independent Activation of rrnB P1: An "Extended" Promoter with an Upstream Element that Dramatically Increases Promoter Strength

    Lin Rao;W. Ross;J. A. Appleman;T. Gaal

  • Expression of rRNA and tRNA genes in Escherichia coli: Evidence for feedback regulation by products of rRNA operons

    Sue Jinks-Robertson;Richard L. Gourse;Masayasu Nomura

  • Bacterial promoter architecture: subsite structure of UP elements and interactions with the carboxy-terminal domain of the RNA polymerase alpha subunit.

    S. T. Estrem;W. Ross;T. Gaal;Z. W. S. Chen

Frequent Co-Authors

Wilma Ross
Wilma Ross University of Wisconsin–Madison
Richard H. Ebright
Richard H. Ebright Rutgers, The State University of New Jersey
Seth A. Darst
Seth A. Darst Rockefeller University
Elizabeth A. Campbell
Elizabeth A. Campbell Rockefeller University
Masayasu Nomura
Masayasu Nomura University of Wisconsin–Madison
Timothy J. Donohue
Timothy J. Donohue University of Wisconsin–Madison
Reid C. Johnson
Reid C. Johnson University of California, Los Angeles
Robert Landick
Robert Landick University of Wisconsin–Madison
Thomas J. Silhavy
Thomas J. Silhavy Princeton University
Konstantin Severinov
Konstantin Severinov Rutgers, The State University of New Jersey

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