World's Best Scientists 2026 revealed!
Norio Komatsu

Norio Komatsu

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
10680
World Ranking
13935
National Ranking
976

Overview

Norio Komatsu is affiliated with Juntendo University in Japan and has made significant contributions to the field of medicine, with a strong focus on genetics and hematology. Their research output spans over 349 publications in medicine, including prominent subfields such as genetics (123 publications), hematology (105 publications), molecular biology (46 publications), rheumatology (44 publications), and pathology and forensic medicine (15 publications).

Their work covers multiple major topics within medical research, notably:

  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Eosinophilic Disorders and Syndromes
  • Chronic Myeloid Leukemia Treatments
  • Acute Myeloid Leukemia Research
  • Kruppel-like factors research
  • Hemoglobinopathies and Related Disorders
  • Lymphoma Diagnosis and Treatment

Among Komatsu's recent papers are:

  • Independent origins of fetal liver haematopoietic stem and progenitor cells, 2022, Nature
  • Prognostic impact of CEBPA bZIP domain mutation in acute myeloid leukemia, 2021, Blood Advances
  • Persistent COVID-19 Pneumonia and Failure to Develop Anti-SARS-CoV-2 Antibodies During Rituximab Maintenance Therapy for Follicular Lymphoma, 2020, Clinical Lymphoma Myeloma & Leukemia
  • Efficacy and safety of a novel dosing strategy for ruxolitinib in the treatment of patients with myelofibrosis and anemia: the REALISE phase 2 study, 2021, Leukemia
  • Dual-antigen targeted iPSC-derived chimeric antigen receptor-T cell therapy for refractory lymphoma, 2021, Molecular Therapy

Komatsu frequently publishes in the following venues:

  • International Journal of Hematology (23 publications)
  • Blood (16 publications)
  • Clinical Lymphoma Myeloma & Leukemia (10 publications)
  • Internal Medicine (6 publications)
  • Hematology (6 publications)

The scientist collaborates regularly with a number of researchers, including:

  • Yoko Edahiro (43 co-authored works)
  • Miki Ando (36 co-authored works)
  • Marito Araki (33 co-authored works)
  • Soji Morishita (33 co-authored works)
  • Kazuya Shimoda (27 co-authored works)

Best Publications

  • Establishment and characterization of a human leukemic cell line with megakaryocytic features: dependency on granulocyte-macrophage colony-stimulating factor, interleukin 3, or erythropoietin for growth and survival.

    Norio Komatsu;Hiromitsu Nakauchi;Hiromitsu Nakauchi;Akiyoshi Miwa;Akiyoshi Miwa;Toshiki Ishihara

  • Different promoter usage and multiple transcription initiation sites of the interleukin-1 receptor-related human ST2 gene in UT-7 and TM12 cells

    Hiroyuki Iwahana;Ken Yanagisawa;Akiko Ito-Kosaka;Kenji Kuroiwa

  • Activation of the thrombopoietin receptor by mutant calreticulin in CALR-mutant myeloproliferative neoplasms

    Marito Araki;Yinjie Yang;Nami Masubuchi;Yumi Hironaka

  • Establishment and characterization of an erythropoietin-dependent subline, UT-7/Epo, derived from human leukemia cell line. UT-7

    N Komatsu;M Yamamoto;H Fujita;A Miwa

  • miR-135b mediates NPM-ALK-driven oncogenicity and renders IL-17-producing immunophenotype to anaplastic large cell lymphoma.

    Hironori Matsuyama;Hiroshi I. Suzuki;Hikaru Nishimori;Masaaki Noguchi

  • A member of Forkhead family transcription factor, FKHRL1, is one of the downstream molecules of phosphatidylinositol 3-kinase-Akt activation pathway in erythropoietin signal transduction

    Yoshifumi Kashii;Mie Uchida;Keita Kirito;Masaru Tanaka

  • A Truncated Erythropoietin Receptor That Fails to Prevent Programmed Cell Death of Erythroid Cells

    Yukio Nakamura;Norio Komatsu;Hiromitsu Nakauchi

  • Growth and differentiation of a human megakaryoblastic cell line, CMK.

    N Komatsu;T Suda;M Moroi;N Tokuyama

  • First continuous propagation of B19 parvovirus in a cell line

    Satoshi Shimomura;Norio Komatsu;Norbert Frickhofen;Stacie Anderson

  • Establishment and characterization of the thrombopoietin-dependent megakaryocytic cell line, UT-7/TPO.

    Norio Komatsu;Masae Kunitama;Minami Yamada;Tetsuya Hagiwara

  • Presence and expression of a novel variant form of ST2 gene product in human leukemic cell line UT-7/GM.

    Shin-ichi Tominaga;Kenji Kuroiwa;Kenji Tago;Hiroyuki Iwahana

  • Leukocyte concentration and composition in platelet-rich plasma (PRP) influences the growth factor and protease concentrations

    Yohei Kobayashi;Yoshitomo Saita;Hirofumi Nishio;Hiroshi Ikeda

  • Thrombopoietin Regulates Bcl-xL Gene Expression through Stat5 and Phosphatidylinositol 3-Kinase Activation Pathways

    Keita Kirito;Tomoko Watanabe;Ken-ichi Sawada;Hitoshi Endo

  • A Member of Forkhead Transcription Factor FKHRL1 Is a Downstream Effector of STI571-induced Cell Cycle Arrest in BCR-ABL-expressing Cells

    Norio Komatsu;Tomoko Watanabe;Mie Uchida;Masaki Mori

  • Ascorbic acid restores sensitivity to imatinib via suppression of Nrf2-dependent gene expression in the imatinib-resistant cell line.

    Takahisa Tarumoto;Tadashi Nagai;Ken Ohmine;Takuji Miyoshi

  • The impact of myeloproliferative neoplasms (MPNs) on patient quality of life and productivity: results from the international MPN Landmark survey

    Claire N. Harrison;Steffen Koschmieder;Lynda Foltz;Paola Guglielmelli

  • Erythropoietin induces tyrosine phosphorylation and activation of phospholipase C-gamma 1 in a human erythropoietin-dependent cell line.

    Han-Yun Ren;N. Komatsu;R. Shimizu;K. Okada

  • Thrombopoietin enhances expression of vascular endothelial growth factor (VEGF) in primitive hematopoietic cells through induction of HIF-1α

    Keita Kirito;Norma Fox;Norma Fox;Norio Komatsu;Norio Komatsu;Kenneth Kaushansky;Kenneth Kaushansky

  • Characterization of stage progression in chronic myeloid leukemia by DNA microarray with purified hematopoietic stem cells.

    Ken Ohmine;Jun Ota;Masuzu Ueda;Shu-ichi Ueno

  • Construction of ELISA system to quantify human ST2 protein in sera of patients.

    K. Kuroiwa;Hongjie Li;K. Tago;H. Iwahana

Frequent Co-Authors

Yasusada Miura
Yasusada Miura Jichi Medical University
Keiya Ozawa
Keiya Ozawa Jichi Medical University
Yusuke Furukawa
Yusuke Furukawa Jichi Medical University
Toshio Suda
Toshio Suda National University of Singapore
Hiromitsu Nakauchi
Hiromitsu Nakauchi Stanford University
Takashi Kato
Takashi Kato Waseda University
Ruben A. Mesa
Ruben A. Mesa The University of Texas Health Science Center at San Antonio
Kazuya Shimoda
Kazuya Shimoda University of Miyazaki
Satoshi Tsuneda
Satoshi Tsuneda Waseda University
Minoru Yoshida
Minoru Yoshida University of Tokyo

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