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Biology and Biochemistry

D-Index
56
Citations
9929
World Ranking
14560
National Ranking
1031

Overview

Yusuke Furukawa is affiliated with Jichi Medical University in Japan and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research primarily focuses on molecular biology and hematology, with significant work in health, toxicology and mutagenesis, pulmonary and respiratory medicine, as well as radiology, nuclear medicine and imaging.

The main topics covered in Yusuke Furukawa's work include:

  • Multiple Myeloma Research and Treatments
  • Protein Degradation and Inhibitors
  • Air Quality and Health Impacts
  • Occupational and Environmental Lung Diseases
  • Occupational Exposure and Asthma
  • Monoclonal and Polyclonal Antibodies Research
  • Peptidase Inhibition and Analysis

Yusuke Furukawa has collaborated frequently with several coauthors, including:

  • Jiro Kikuchi
  • Shigeyuki Hirai
  • Hideki Senoh
  • Kyohei Misumi
  • Kenji Takanobu

The scientist has published in several prominent journals. The most frequent publication venues include:

  • European Heart Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • The Journal of Toxicological Sciences
  • Particle and Fibre Toxicology

Among recent papers authored or coauthored by Yusuke Furukawa are:

  • "Splicing- and demethylase-independent functions of LSD1 in zebrafish primitive hematopoiesis," 2020, Scientific Reports
  • "Molecular basis of clonal evolution in multiple myeloma," 2020, International Journal of Hematology
  • "Pulmonary dust foci as rat pneumoconiosis lesion induced by titanium dioxide nanoparticles in 13-week inhalation study," 2022, Particle and Fibre Toxicology
  • "Novel hepatotoxicity biomarkers of extracellular vesicle (EV)-associated miRNAs induced by CCl4," 2020, Toxicology Reports
  • "No evidence for carcinogenicity of titanium dioxide nanoparticles in 26-week inhalation study in rasH2 mouse model," 2022, Scientific Reports

Best Publications

  • The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element.

    James A. DeCaprio;John W. Ludlow;Dennis Lynch;Yusuke Furukawa

  • Signal transduction of the human granulocyte-macrophage colony- stimulating factor and interleukin-3 receptors involves tyrosine phosphorylation of a common set of cytoplasmic proteins

    Yuzuru Kanakura;Brian Druker;Stephen A. Cannistra;Yusuke Furukawa

  • In vitro cytotoxic effects of a tyrosine kinase inhibitor STI571 in combination with commonly used antileukemic agents

    Yasuhiko Kano;Miyuki Akutsu;Saburo Tsunoda;Hiroyuki Mano

  • The retinoblastoma-susceptibility gene product becomes phosphorylated in multiple stages during cell cycle entry and progression.

    James A. Decaprio;Yusuke Furukawa;Florence Ajchenbaum;James D. Griffin

  • cdc2 gene expression at the G1 to S transition in human T lymphocytes

    Yusuke Furukawa;Helen Piwnica-Worms;Timothy J. Ernst;Yuzuru Kanakura

  • Bortezomib overcomes cell-adhesion-mediated drug resistance through downregulation of VLA-4 expression in multiple myeloma

    K Noborio-Hatano;J Kikuchi;M Takatoku;R Shimizu

  • A Janus Kinase Inhibitor, JAB, Is an Interferon-γ–Inducible Gene and Confers Resistance to Interferons

    Hiroshi Sakamoto;Hideo Yasukawa;Masaaki Masuhara;Shyu Tanimura

  • Apaf-1 is a mediator of E2F-1-induced apoptosis.

    Yusuke Furukawa;Noriko Nishimura;Yutaka Furukawa;Masaaki Satoh

  • Expression and state of phosphorylation of the retinoblastoma susceptibility gene product in cycling and noncycling human hematopoietic cells

    Y Furukawa;J A DeCaprio;A Freedman;Y Kanakura

  • Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma

    Jiro Kikuchi;Taeko Wada;Rumi Shimizu;Tohru Izumi

  • Phosphorylation of Bcl-2 Protein by CDC2 Kinase during G2/M Phases and Its Role in Cell Cycle Regulation

    Yusuke Furukawa;Satsuki Iwase;Jiro Kikuchi;Yasuhito Terui

  • The Expression of ST2 Gene in Helper T Cells and the Binding of ST2 Protein to Myeloma-Derived RPMI8226 Cells

    Ken Yanagisawa;Yoshiyuki Naito;Kenji Kuroiwa;Takao Arai

  • Direct Transcriptional Activation of Human Caspase-1 by Tumor Suppressor p53

    Sanjeev Gupta;Vegesna Radha;Yusuke Furukawa;Ghanshyam Swarup

  • HDAC inhibitors augment cytotoxic activity of rituximab by upregulating CD20 expression on lymphoma cells.

    R. Shimizu;J. J. Kikuchi;T. Wada;K. Ozawa

  • Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis.

    Motohiro Sekiya;Jun-ichi Osuga;Jun-ichi Osuga;Shuichi Nagashima;Taichi Ohshiro

  • Treatment of myeloid leukemic cells with the phosphatase inhibitor okadaic acid induces cell cycle arrest at either G1/S or G2/M depending on dose

    Yuji Ishida;Yusuke Furukawa;James A. Decaprio;Masaki Saito

  • Lineage-specific regulation of cell cycle control gene expression during haematopoietic cell differentiation

    Yusuke Furukawa;Jiro Kikuchi;Mitsuru Nakamura;Satsuki Iwase

  • Phosphorylation-mediated EZH2 inactivation promotes drug resistance in multiple myeloma

    Jiro Kikuchi;Daisuke Koyama;Taeko Wada;Tohru Izumi

  • Transcriptional Modulation Using HDACi Depsipeptide Promotes Immune Cell-Mediated Tumor Destruction of Murine B16 Melanoma

    Takashi Murakami;Atsuko Sato;Nicole A L Chun;Mayumi Hara

  • Efficient ejection of H3(+) from hydrocarbon molecules induced by ultrashort intense laser fields.

    Kennosuke Hoshina;Yusuke Furukawa;Tomoya Okino;Kaoru Yamanouchi

Frequent Co-Authors

Norio Komatsu
Norio Komatsu Juntendo University
Yasusada Miura
Yasusada Miura Jichi Medical University
James D. Griffin
James D. Griffin Harvard University
Keiya Ozawa
Keiya Ozawa Jichi Medical University
Hiroyuki Mano
Hiroyuki Mano University of Tokyo
Masaki Mori
Masaki Mori Kyushu University
Koshi Mimori
Koshi Mimori Kyushu University
James A. DeCaprio
James A. DeCaprio Harvard University
Shun Ishibashi
Shun Ishibashi Jichi Medical University

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