World's Best Scientists 2026 revealed!

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Medicine

D-Index
92
Citations
32936
World Ranking
11261
National Ranking
326

Overview

Shun Ishibashi is affiliated with Jichi Medical University in Japan and has contributed extensively to the field of medicine, with a focus primarily on cardiology and cardiovascular medicine. Their research spans various subfields including surgery, molecular biology, endocrinology, diabetes and metabolism, as well as radiology, nuclear medicine, and imaging.

The scientist's work covers a range of topics central to cardiovascular and metabolic health. Key research interests include acute myocardial infarction, cardiac imaging and diagnostics, lipoproteins and cardiovascular health, coronary interventions and diagnostics, lipid metabolism and disorders, as well as the intersection of diabetes with cardiovascular risks and lipoproteins and diabetes treatment and management.

Shun Ishibashi has published numerous papers in several respected journals, with frequent contributions in the following publication venues:

  • Journal of Atherosclerosis and Thrombosis
  • Cardiovascular Intervention and Therapeutics
  • Internal Medicine
  • Journal of Clinical Lipidology
  • Scientific Reports

Among recent notable publications are:

  • "Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2022," 2023, Journal of Atherosclerosis and Thrombosis
  • "Inhibition of 7-dehydrocholesterol reductase prevents hepatic ferroptosis under an active state of sterol synthesis," 2024, Nature Communications
  • "Guidance for the diagnosis and treatment of hypolipidemia disorders," 2022, Journal of Clinical Lipidology
  • "Effects of luseogliflozin on arterial properties in patients with type 2 diabetes mellitus: The multicenter, exploratory LUSCAR study," 2020, Journal of Clinical Hypertension
  • "Current Diagnosis and Management of Abetalipoproteinemia," 2021, Journal of Atherosclerosis and Thrombosis

Frequent coauthors in their research include:

  • Kenichi Sakakura
  • Yousuke Taniguchi
  • Hiroyuki Jinnouchi
  • Takunori Tsukui
  • Kei Yamamoto

Their total output encompasses nearly 200 publications in the field of medicine, illustrating a sustained engagement with research on cardiovascular diseases, metabolic disorders, and associated diagnostic techniques. This body of work reflects a commitment to advancing knowledge on conditions related to heart health, lipid metabolism, and diabetes complications.

Best Publications

  • Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery.

    Shun Ishibashi;Michael S Brown;Joseph L Goldstein;Robert D. Gerard

  • A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection

    Hiroshi Suzuki;Hiroshi Suzuki;Yukiko Kurihara;Motohiro Takeya;Nobuo Kamada

  • High cholesterol level is essential for myelin membrane growth.

    Gesine Saher;Britta Brügger;Corinna Lappe-Siefke;Wiebke Möbius

  • Sterol Regulatory Element-binding Protein-1 as a Key Transcription Factor for Nutritional Induction of Lipogenic Enzyme Genes

    Hitoshi Shimano;Naoya Yahagi;Michiyo Amemiya-Kudo;Alyssa H. Hasty

  • Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2017.

    Makoto Kinoshita;Koutaro Yokote;Hidenori Arai;Mami Iida

  • Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity

    Jun-ichi Osuga;Shun Ishibashi;Teruaki Oka;Hiroaki Yagyu

  • Executive Summary of the Japan Atherosclerosis Society (JAS) Guidelines for the Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases in Japan —2012 Version

    Tamio Teramoto;Jun Sasaki;Shun Ishibashi;Sadatoshi Birou

  • Identification of Liver X Receptor-Retinoid X Receptor as an Activator of the Sterol Regulatory Element-Binding Protein 1c Gene Promoter

    Tomohiro Yoshikawa;Hitoshi Shimano;Michiyo Amemiya-Kudo;Naoya Yahagi

  • The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins

    Shun Ishibashi;Joachim Herz;Nobuyo Maeda;Joseph L. Goldstein

  • Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements

    Tomohiro Yoshikawa;Hitoshi Shimano;Naoya Yahagi;Tomohiro Ide

  • Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression.

    Motohiro Sekiya;Naoya Yahagi;Takashi Matsuzaka;Yuho Najima

  • Transcriptional activities of nuclear SREBP-1a, -1c, and -2 to different target promoters of lipogenic and cholesterogenic genes

    Michiyo Amemiya-Kudo;Hitoshi Shimano;Alyssa H. Hasty;Naoya Yahagi

  • Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice.

    Naoya Yahagi;Hitoshi Shimano;Alyssa H. Hasty;Takashi Matsuzaka

  • Hypoadiponectinemia is associated with visceral fat accumulation and insulin resistance in Japanese men with type 2 diabetes mellitus.

    Toshimitsu Yatagai;Shoichiro Nagasaka;Ataru Taniguchi;Mitsuo Fukushima

  • A Crucial Role of Sterol Regulatory Element-binding Protein-1 in the Regulation of Lipogenic Gene Expression by Polyunsaturated Fatty Acids

    Naoya Yahagi;Hitoshi Shimano;Alyssa H. Hasty;Michiyo Amemiya-Kudo

  • Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist

    Thomas E. Willnow;Zeqi Sheng;Shun Ishibashi;Joachim Herz

  • Troglitazone Inhibits Atherosclerosis in Apolipoprotein E–Knockout Mice: Pleiotropic Effects on CD36 Expression and HDL

    Zhong Chen;Shun Ishibashi;Stéphane Perrey;Jun-ichi Osuga

  • Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling.

    Tomohiro Yoshikawa;Tomohiro Ide;Hitoshi Shimano;Naoya Yahagi

  • Effects of statins on the adipocyte maturation and expression of glucose transporter 4 (SLC2A4): implications in glycaemic control

    M. Nakata;S. Nagasaka;I. Kusaka;H. Matsuoka

  • Dual regulation of mouse Δ5- and Δ6-desaturase gene expression by SREBP-1 and PPARα

    Takashi Matsuzaka;Hitoshi Shimano;Naoya Yahagi;Michiyo Amemiya-Kudo

Frequent Co-Authors

Nobuhiro Yamada
Nobuhiro Yamada University of Tsukuba
Hitoshi Shimano
Hitoshi Shimano University of Tsukuba
Takanari Gotoda
Takanari Gotoda Kyorin University
Shizuya Yamashita
Shizuya Yamashita Osaka University
Naoya Yahagi
Naoya Yahagi University of Tsukuba
Hirohito Sone
Hirohito Sone Niigata University
Hidenori Arai
Hidenori Arai Kyoto University
Ryozo Nagai
Ryozo Nagai Jichi Medical University
Yoshio Yazaki
Yoshio Yazaki University of Tokyo
Takashi Kadowaki
Takashi Kadowaki Toranomon Hospital

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