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Dominique Langin

Dominique Langin

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Medicine
France
2023

D-Index & Metrics

Medicine

D-Index
101
Citations
34614
World Ranking
8036
National Ranking
248

Research.com Recognitions

  • 2023 - Research.com Medicine in France Leader Award

Overview

Dominique Langin is affiliated with Inserm in France and has contributed extensively to research in medicine, particularly focusing on adipose tissue and metabolism. Their work spans several interconnected fields, including biochemistry, genetics, molecular biology, physiology, molecular biology, biochemistry, epidemiology, and cardiology and cardiovascular medicine.

Their research covers diverse topics with a strong emphasis on metabolic processes, such as adipose tissue and metabolism, lipid metabolism and biosynthesis, adipokines, inflammation, and metabolic diseases. Additionally, Langin has explored diet and metabolism studies, nutrition and health in aging, GDF15 and related biomarkers, and dietary effects on health.

Langin's recent published papers illustrate the range and depth of their work. Notable publications include:

  • Lipid and glucose metabolism in white adipocytes: pathways, dysfunction and therapeutics (2021) in Nature Reviews Endocrinology
  • An integrated single cell and spatial transcriptomic map of human white adipose tissue (2023) in Nature Communications
  • In vitro and ex vivo models of adipocytes (2021) in American Journal of Physiology-Cell Physiology
  • Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity (2020) in Scientific Reports
  • Growth and differentiation factor 15 is secreted by skeletal muscle during exercise and promotes lipolysis in humans (2020) in JCI Insight

Langin has collaborated frequently with several researchers, including:

  • Nathalie Viguerie
  • Sophie Guyonnet
  • Mikael Rydén
  • Étienne Mouisel
  • Peter Arner

Their work has been published repeatedly in journals such as Cell Metabolism, Nature Communications, JCI Insight, The Journal of Clinical Endocrinology & Metabolism, and bioRxiv (Cold Spring Harbor Laboratory), reflecting a consistent focus on metabolism and related biomedical sciences.

Best Publications

  • Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss.

    Raffaella Cancello;Corneliu Henegar;Nathalie Viguerie;Soraya Taleb

  • Transcriptional Control of Brown Fat Determination by PRDM16

    Patrick Seale;Shingo Kajimura;Wenli Yang;Sherry Chin

  • Genome-wide gene-based analyses of weight loss interventions identify a potential role for NKX6.3 in metabolism.

    Armand Valsesia;Qiao-Ping Wang;Qiao-Ping Wang;Nele Gheldof;Jerome Carayol

  • Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects

    Karine Clément;Nathalie Viguerie;Nathalie Viguerie;Christine Poitou;Claire Carette

  • Lipolysis and lipid mobilization in human adipose tissue

    Max Lafontan;Max Lafontan;Dominique Langin;Dominique Langin

  • Functional beta3-adrenoceptor in the human heart.

    C Gauthier;G Tavernier;F Charpentier;D Langin

  • Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD

    Alexandra Montagner;Arnaud Polizzi;Edwin Fouché;Simon Ducheix

  • Acquirement of brown fat cell features by human white adipocytes.

    Claire Tiraby;Geneviève Tavernier;Corinne Lefort;Dominique Larrouy

  • Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity

    Corneliu Henegar;Joan Tordjman;Vincent Achard;Danièle Lacasa

  • Adipocyte lipolysis and insulin resistance

    Pauline Morigny;Marianne Houssier;Etienne Mouisel;Dominique Langin;Dominique Langin;Dominique Langin

  • Increased uncoupling protein-2 and -3 mRNA expression during fasting in obese and lean humans.

    L Millet;H Vidal;F Andreelli;D Larrouy

  • Adipocyte Lipases and Defect of Lipolysis in Human Obesity

    Dominique Langin;Andrea Dicker;Geneviève Tavernier;Johan Hoffstedt

  • Adipose tissue lipolysis as a metabolic pathway to define pharmacological strategies against obesity and the metabolic syndrome

    Dominique Langin

  • Adipose triglyceride lipase and hormone-sensitive lipase protein expression is decreased in the obese insulin-resistant state.

    Johan W. E. Jocken;Dominique Langin;Dominique Langin;Egbert Smit;Wim H. M. Saris

  • Lipid and glucose metabolism in white adipocytes: pathways, dysfunction and therapeutics

    Pauline Morigny;Jeremie Boucher;Jeremie Boucher;Peter Arner;Dominique Langin

  • Effect of aerobic training on plasma levels and subcutaneous abdominal adipose tissue gene expression of adiponectin, leptin, interleukin 6, and tumor necrosis factor alpha in obese women

    Jan Polak;Eva Klimcakova;Eva Klimcakova;Cedric Moro;Cedric Moro;Nathalie Viguerie;Nathalie Viguerie

  • Effect of endurance training on skeletal muscle myokine expression in obese men: identification of apelin as a novel myokine.

    Besse-Patin A;Montastier E;Vinel C;Castan-Laurell I

  • Site-specific regulation of gene expression by n-3 polyunsaturated fatty acids in rat white adipose tissues.

    T Raclot;R Groscolas;D Langin;P Ferré

  • Contribution of adipose triglyceride lipase and hormone-sensitive lipase to lipolysis in hMADS adipocytes.

    Véronic Bezaire;Véronic Bezaire;Aline Mairal;Aline Mairal;Carole Ribet;Carole Ribet;Corinne Lefort;Corinne Lefort

  • Lipolysis in lipid turnover, cancer cachexia, and obesity-induced insulin resistance

    Peter Arner;Dominique Langin

Frequent Co-Authors

Wim H. M. Saris
Wim H. M. Saris Maastricht University
Peter Arner
Peter Arner Karolinska Institute
Arne Astrup
Arne Astrup Novo Nordisk Foundation
Cecilia Holm
Cecilia Holm Lund University
Thorkild I. A. Sørensen
Thorkild I. A. Sørensen University of Copenhagen
Hubert Vidal
Hubert Vidal Claude Bernard University Lyon 1
Ez-Zoubir Amri
Ez-Zoubir Amri Grenoble Alpes University
Mikael Rydén
Mikael Rydén Karolinska University Hospital

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