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Medicine

D-Index
88
Citations
25066
World Ranking
13273
National Ranking
434

Overview

Matthew J. Watt is a researcher affiliated with the University of Melbourne in Australia. Their work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a strong focus on several subfields including Molecular Biology, Physiology, Epidemiology, Surgery, and Cancer Research.

Their research covers a range of topics related to metabolism and disease, with key interests in:

  • Adipose Tissue and Metabolism
  • Liver Disease Diagnosis and Treatment
  • Pancreatic Function and Diabetes
  • Adipokines, Inflammation, and Metabolic Diseases
  • Exercise and Physiological Responses
  • Regulation of Appetite and Obesity
  • Cancer, Lipids, and Metabolism

Matthew J. Watt's body of published work includes several recent papers such as:

  • "Exerkines in health, resilience and disease," published in 2022 in Nature Reviews Endocrinology
  • "Epicardial Adipose Tissue Accumulation Confers Atrial Conduction Abnormality," published in 2020 in the Journal of the American College of Cardiology
  • "Metabolic communication during exercise," published in 2020 in Nature Metabolism
  • "Hepatic lipidomic remodeling in severe obesity manifests with steatosis and does not evolve with non-alcoholic steatohepatitis," published in 2021 in the Journal of Hepatology
  • "Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function," published in 2022 in Cell Metabolism

Frequent collaborators of Watt include Magdalene K. Montgomery, Stacey N. Keenan, William De Nardo, Jacqueline Bayliss, and Paula M. Miotto.

Their research findings have appeared multiple times in several key journals, with contributions notably to:

  • American Journal of Physiology-Endocrinology and Metabolism
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Molecular Metabolism
  • Nature Metabolism

Best Publications

  • Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase

    Andrew L Carey;Gregory R Steinberg;S Lance Macaulay;Walter G Thomas

  • Brain-derived neurotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP-activated protein kinase

    Vance B Matthews;M-B Astrom;M H S Chan;Clinton R Bruce

  • Reactive oxygen species enhance insulin sensitivity.

    Kim Yong Loh;Haiyang Deng;Atsushi Fukushima;Xiaochu Cai

  • HSP72 protects against obesity-induced insulin resistance.

    Jason Chung;Anh-Khoi Nguyen;Darren C Colin Henstridge;Anna G Holmes

  • Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver

    Mara Monetti;Malin C. Levin;Matthew J. Watt;Mini P. Sajan

  • Macrophage PPARγ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones

    Andrea L Hevener;Jerrold M Olefsky;Donna Reichart;MT Audrey Nguyen

  • Tumor necrosis factor α-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling

    Gregory r Steinberg;Belinda J Michell;Bryce J W Jw van Denderen;Matthew James Watt

  • Hepatokines: linking nonalcoholic fatty liver disease and insulin resistance

    Ruth C. R. Meex;Ruth C. R. Meex;Matthew J. Watt

  • The Liver as an Endocrine Organ-Linking NAFLD and Insulin Resistance.

    Matthew J Watt;Paula M Miotto;William De Nardo;Magdalene K Montgomery

  • Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance.

    Clinton R Bruce;Andrew James Hoy;Nigel Turner;Matthew James Watt

  • Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance

    Vance B Matthews;T L Allen;S Risis;M H S Chan

  • Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites

    Jong Sam Lee;S K Pinnamaneni;Su Ju Eo;In Ho Cho

  • Impaired oxidative metabolism and inflammation are associated with insulin resistance in ERα-deficient mice

    Vicent Ribas;M T Audrey Nguyen;Darren C Henstridge;Darren C Henstridge;Anh Khoi Nguyen

  • Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC.

    Marcus Grohmann;Florian Wiede;Garron Gt Dodd;Esteban Nicolas Gurzov

  • CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK

    Matthew James Watt;Nicolas Dzamko;Walter G Thomas;Stefan Rose-John

  • Ceramides Contained in LDL Are Elevated in Type 2 Diabetes and Promote Inflammation and Skeletal Muscle Insulin Resistance

    James Yew Chong Boon;Andrew J Hoy;Romana Stark;Russell D Brown

  • Regulation of HSL serine phosphorylation in skeletal muscle and adipose tissue

    Matthew James Watt;Anna G Holmes;S K Pinnamaneni;Andrew P Garnham

  • Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer

    Matthew J. Watt;Matthew J. Watt;Ashlee K. Clark;Luke A. Selth;Vanessa R. Haynes;Vanessa R. Haynes

  • Intramuscular triacylglycerol, glycogen and acetyl group metabolism during 4 h of moderate exercise in man

    Matthew James Watt;George J F Heigenhauser;David J Dyck;Lawrence L Spriet

  • Decreased PDH activation and glycogenolysis during exercise following fat adaptation with carbohydrate restoration

    Trent Stellingwerff;Lawrence L Spriet;Matthew James Watt;Nicholas E Kimber

Frequent Co-Authors

Mark A. Febbraio
Mark A. Febbraio Monash University
Bruce E. Kemp
Bruce E. Kemp Australian Catholic University
Gregory R. Steinberg
Gregory R. Steinberg McMaster University
Mark Hargreaves
Mark Hargreaves University of Melbourne
Lawrence L. Spriet
Lawrence L. Spriet University of Guelph
George J. F. Heigenhauser
George J. F. Heigenhauser McMaster University
John A. Hawley
John A. Hawley Australian Catholic University
Tony Tiganis
Tony Tiganis Peter MacCallum Cancer Centre
Peter J. Meikle
Peter J. Meikle Baker IDI Heart and Diabetes Institute
Brian J. Oldfield
Brian J. Oldfield Monash University

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