D-Index & Metrics Best Publications
Research.com 2022 Best Scientist Award Badge
Medicine
USA
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Best Scientists D-index 186 Citations 145,758 631 World Ranking 343 National Ranking 229
Medicine D-index 187 Citations 143,683 625 World Ranking 152 National Ranking 98

Research.com Recognitions

Awards & Achievements

2023 - Research.com Medicine in United States Leader Award

2022 - Research.com Best Scientist Award

2018 - Fellow of the American Academy of Arts and Sciences

2009 - Fellow of the American Association for the Advancement of Science (AAAS)

2007 - Member of the National Academy of Sciences

2005 - Member of the National Academy of Medicine (NAM)

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Gene
  • Enzyme

Gerald I. Shulman focuses on Endocrinology, Internal medicine, Insulin resistance, Insulin and Type 2 diabetes. His Endocrinology study focuses mostly on Diabetes mellitus, Carbohydrate metabolism, Glycogen synthase, Glucose clamp technique and Skeletal muscle. Adipose tissue, Glucose uptake, Glucose transporter, Glycogen and Gluconeogenesis are the subjects of his Internal medicine studies.

His Insulin resistance research includes elements of Nonalcoholic fatty liver disease, Fatty liver, Steatosis and Type 2 Diabetes Mellitus. Insulin and Offspring are commonly linked in his work. His Type 2 diabetes research includes themes of Acetyl-CoA carboxylase and Mitochondrion.

His most cited work include:

  • Cellular mechanisms of insulin resistance (2308 citations)
  • Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. (1798 citations)
  • Mitochondrial dysfunction in the elderly: possible role in insulin resistance (1696 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Internal medicine, Endocrinology, Insulin resistance, Insulin and Type 2 diabetes. His Internal medicine study frequently draws parallels with other fields, such as Diabetes mellitus. His study in Insulin receptor, Adipose tissue, Glycogen, Glycogen synthase and Carbohydrate metabolism falls within the category of Endocrinology.

His biological study spans a wide range of topics, including Steatosis, Lipogenesis, Lipid metabolism, Diacylglycerol kinase and Nonalcoholic fatty liver disease. In his work, Glycogenolysis and Pyruvate carboxylase is strongly intertwined with Gluconeogenesis, which is a subfield of Insulin. His Mitochondrion research extends to the thematically linked field of Type 2 diabetes.

He most often published in these fields:

  • Internal medicine (88.50%)
  • Endocrinology (87.58%)
  • Insulin resistance (50.46%)

What were the highlights of his more recent work (between 2017-2021)?

  • Internal medicine (88.50%)
  • Endocrinology (87.58%)
  • Insulin resistance (50.46%)

In recent papers he was focusing on the following fields of study:

Gerald I. Shulman mainly focuses on Internal medicine, Endocrinology, Insulin resistance, Insulin and Type 2 diabetes. His Insulin resistance study incorporates themes from Nonalcoholic fatty liver disease, Fatty liver and Steatosis. The various areas that he examines in his Nonalcoholic fatty liver disease study include Protein kinase B and Glycogen synthase.

Many of his studies involve connections with topics such as Somatostatin and Insulin. While the research belongs to areas of Type 2 diabetes, he spends his time largely on the problem of Bioinformatics, intersecting his research to questions surrounding Obesity. His study looks at the relationship between Insulin receptor and topics such as Kinase, which overlap with Signal transduction.

Between 2017 and 2021, his most popular works were:

  • Mechanisms of Insulin Action and Insulin Resistance (379 citations)
  • Nonalcoholic Fatty Liver Disease as a Nexus of Metabolic and Hepatic Diseases (216 citations)
  • The integrative biology of type 2 diabetes. (132 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Enzyme

Gerald I. Shulman mainly investigates Insulin resistance, Endocrinology, Internal medicine, Type 2 diabetes and Nonalcoholic fatty liver disease. Gerald I. Shulman is doing genetic studies as part of his Insulin and Diabetes mellitus and Insulin resistance investigations. His study involves Steatosis, Lipid metabolism, Gluconeogenesis, Lipolysis and Adipose tissue, a branch of Endocrinology.

Gerald I. Shulman interconnects Glucagon, Adipose triglyceride lipase and Fatty liver in the investigation of issues within Steatosis. Gerald I. Shulman has researched Type 2 diabetes in several fields, including Pathogenesis, Bioinformatics, Transcriptome, Transcription factor and White adipose tissue. His Nonalcoholic fatty liver disease study also includes

  • Lipogenesis, which have a strong connection to Acetyl-CoA carboxylase and Glycogen synthase,
  • Hypertriglyceridemia, which have a strong connection to Lipoprotein, Pharmacology and Metabolic syndrome.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Cellular mechanisms of insulin resistance

Gerald I. Shulman.
Journal of Clinical Investigation (2000)

3647 Citations

Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes.

Kitt Falk Petersen;Sylvie Dufour;Douglas Befroy;Rina Garcia.
The New England Journal of Medicine (2004)

2473 Citations

Mitochondrial dysfunction and type 2 diabetes.

Bradford B. Lowell;Gerald I. Shulman.
Science (2005)

2439 Citations

Mitochondrial dysfunction in the elderly: possible role in insulin resistance

Kitt Falk Petersen;Douglas Befroy;Sylvie Dufour;James Dziura.
Science (2003)

2355 Citations

Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)

Han Cho;James Mu;Jason K. Kim;Jason K. Kim;Joanne L. Thorvaldsen.
Science (2001)

2253 Citations

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

Jorge Alejandro Henao-Mejía;Eran Elinav;Cheng Cheng Jin;Liming Hao.
Nature (2012)

2241 Citations

Mechanisms for insulin resistance: common threads and missing links.

Varman T. Samuel;Gerald I. Shulman.
Cell (2012)

2190 Citations

Disruption of IRS-2 causes type 2 diabetes in mice

Dominic J. Withers;Julio Sanchez Gutierrez;Heather Towery;Deborah J. Burks.
Nature (1998)

2049 Citations

Mechanism of free fatty acid-induced insulin resistance in humans.

Michael Roden;Thomas B. Price;Gianluca Perseghin;Kitt Falk Petersen.
Journal of Clinical Investigation (1996)

1955 Citations

Mechanism by Which Fatty Acids Inhibit Insulin Activation of Insulin Receptor Substrate-1 (IRS-1)-associated Phosphatidylinositol 3-Kinase Activity in Muscle *

Chunli Yu;Yan Chen;Gary W. Cline;Dongyan Zhang.
Journal of Biological Chemistry (2002)

1823 Citations

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