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Biology and Biochemistry

D-Index
141
Citations
79779
World Ranking
258
National Ranking
175

Medicine

D-Index
141
Citations
79779
World Ranking
1614
National Ranking
941

Overview

Morris F. White is affiliated with Boston Children's Hospital in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Within these domains, their work includes subfields such as Molecular Biology, Physiology, Surgery, Endocrinology, Diabetes and Metabolism, and Epidemiology.

The scientist's research focuses notably on topics like Adipose Tissue and Metabolism, Pancreatic Function and Diabetes, Metabolism, Diabetes, and Cancer, Liver Disease Diagnosis and Treatment, Diet, Metabolism, and Disease, Muscle Physiology and Disorders, and Diabetes Treatment and Management.

Recent publications by Morris F. White include:

  • Insulin action at a molecular level - 100 years of progress, 2021, Molecular Metabolism
  • The role of hepatokines in NAFLD, 2023, Cell Metabolism
  • Elevated circulating follistatin associates with an increased risk of type 2 diabetes, 2021, Nature Communications
  • Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex, 2022, Cell Reports
  • Insulin receptor substrates differentially exacerbate insulin-mediated left ventricular remodeling, 2020, JCI Insight

They have frequently published in venues such as:

  • Diabetes
  • Cell Metabolism
  • Molecular Metabolism
  • Cell Reports
  • Scientific Reports

Morris F. White has collaborated extensively with peers including Rongya Tao, Kyle D. Copps, Oliver Stöhr, Norbert Stefan, and Ji Miao. Their joint work reflects multidisciplinary approaches within their research fields.

Best Publications

  • IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance

    Gökhan S. Hotamisligil;Pascal Peraldi;Adriane Budavari;Ramsey Ellis

  • The insulin signaling system.

    M F White;C R Kahn

  • Disruption of IRS-2 causes type 2 diabetes in mice

    Dominic J. Withers;Julio Sanchez Gutierrez;Heather Towery;Deborah J. Burks

  • Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein.

    Xiao Jian Sun;P. Rothenberg;P. Rothenberg;C. R. Kahn;J. M. Backer

  • Mechanism by Which Fatty Acids Inhibit Insulin Activation of Insulin Receptor Substrate-1 (IRS-1)-associated Phosphatidylinositol 3-Kinase Activity in Muscle *

    Chunli Yu;Yan Chen;Gary W. Cline;Dongyan Zhang

  • The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307).

    Vincent Aguirre;Tohru Uchida;Lynne Yenush;Roger Davis

  • Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade.

    Margaret E. Griffin;Melissa J. Marcucci;Gary W. Cline;Kim Bell

  • Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulation.

    J M Backer;M G Myers;S E Shoelson;D J Chin

  • Phosphorylation of Ser307 in Insulin Receptor Substrate-1 Blocks Interactions with the Insulin Receptor and Inhibits Insulin Action

    Vincent Aguirre;Eric D. Werner;Jodel Giraud;Yong Hee Lee

  • IRS proteins and the common path to diabetes

    Morris F. White

  • Role of IRS-2 in insulin and cytokine signalling

    Xiao Jian Sun;Ling Mei Wang;Yitao Zhang;Lynne Yenush

  • SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2.

    Liangyou Rui;Minsheng Yuan;Daniel Frantz;Steven Shoelson

  • Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2

    K. D. Copps;M. F. White

  • The IRS-signalling system: a network of docking proteins that mediate insulin action.

    Morris F. White

  • Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents

    Katsutaro Morino;Kitt Falk Petersen;Sylvie Dufour;Douglas Befroy

  • Insulin signaling in health and disease.

    Morris F. White

  • The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc : implications for insulin control of ras signalling

    E Y Skolnik;C H Lee;A Batzer;L M Vicentini

  • Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185,000 protein in intact cells

    M F White;R Maron;C R Kahn

  • The insulin signalling system and the IRS proteins

    M. F. White

  • Irs-2 coordinates Igf-1 receptor-mediated β-cell development and peripheral insulin signalling

    Dominic J. Withers;Deborah J. Burks;Heather H. Towery;Shari L. Altamuro

Frequent Co-Authors

Martin G. Myers
Martin G. Myers University of Toronto
Jonathan M. Backer
Jonathan M. Backer Albert Einstein College of Medicine
C. Ronald Kahn
C. Ronald Kahn Harvard University
Lynne Yenush
Lynne Yenush Universitat Politècnica de València
Jacalyn H. Pierce
Jacalyn H. Pierce National Institutes of Health
Steven E. Shoelson
Steven E. Shoelson Harvard University
Dominic J. Withers
Dominic J. Withers Imperial College London
George L. King
George L. King Harvard University
Liangyou Rui
Liangyou Rui University of Michigan–Ann Arbor
Gerald I. Shulman
Gerald I. Shulman Yale University

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